相关论文: Sperry versus Hebb: Topographic mapping in Isl2/Ep…

Axons of retinal ganglion cells establish orderly projections to the superior colliculus of the midbrain. Axons of neighboring cells terminate proximally in the superior colliculus thus forming a topographically precise representation of…

We present a theoretical model for retinocollicular map development, which can account for intriguing behaviors observed in gain-of-function experiments in knock-in mice by Brown et al., including bifurcation in heterozygous Isl2/EphA3…

The neuronal networks in the mammals cortex are characterized by the coexistence of hierarchy, modularity, short and long range interactions, spatial correlations, and topographical connections. Particularly interesting, the latter type of…

Molecular and activity-based cues acting together are thought to guide retinal axons to their terminal sites in vertebrate optic tectum or superior colliculus to form an ordered map of connections. The details of mechanisms involved, and…

Topographic maps are a brain structure connecting pre-synpatic and post-synaptic brain regions. Topographic development is dependent on Hebbian-based plasticity mechanisms working in conjunction with spontaneous patterns of neural activity…

When an object moves smoothly across a field of view, the identify of the object is unchanged, but the activation pattern of the photoreceptors on the retina changes drastically. One of the major computational roles of our visual system is…

A linear neural network is proposed for mamalian vision system in which backward connections from the primary visual cortex (V1) to the lateral geniculate nucleus play a key role. The backward connections control the flow of information…

In the mammalian brain, many neuronal ensembles are involved in representing spatial structure of the environment. In particular, there exist cells that encode the animal's location and cells that encode head direction. A number of studies…

Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic…

Much has been learned about plasticity of biological synapses from empirical studies. Hebbian plasticity is driven by correlated activity of presynaptic and postsynaptic neurons. Synapses that converge onto the same neuron often behave as…

Primary visual cortex (V1) provides crucial insights into the selectivity and emergence of specific output features such as orientation tuning. Tuning and selectivity of cortical neurons in mouse visual cortex is not equivocally resolved so…

Shibata et al. reported that humans could learn to repeatedly evoke a stimulus-associated functional magnetic resonance imaging (fMRI) activity pattern in visual areas V1/V2 through which visual perceptual learning was achieved without…

We analyse the potential effects of lateral connectivity (amacrine cells and gap junctions) on motion anticipation in the retina. Our main result is that lateral connectivity can-under conditions analysed in the paper-trigger a wave of…

Spin polarized scanning tunneling microscopy is used to directly image topological magnetic textures in thin films of MnGe, and to correlate the magnetism with structure probed at the atomic-scale. Our images indicate helical stripe…

Redundancies and correlations in the responses of sensory neurons seem to waste neural resources but can carry cues about structured stimuli and may help the brain to correct for response errors. To assess how the retina negotiates this…

The neocortex is widely believed to be the seat of intelligence and "mind". However, it's unclear what "mind" is, or how the special features of neocortex enable it, though likely "connectionist" principles are involved *A. The key to…

The control of recently observed spintronic effects in topological-insulator/ferromagnetic-metal (TI/FM) heterostructures is thwarted by the lack of understanding of band structure and spin texture around their interfaces. Here we combine…

The retina is the entrance of the visual system. Although based on common biophysical principles the dynamics of retinal neurons is quite different from their cortical counterparts, raising interesting problems for modellers. In this paper…

Experimental data suggest that some classes of spiking neurons in the first layers of sensory systems are electrically coupled via gap junctions or ephaptic interactions. When the electrical coupling is removed, the response function…

Spatial navigation in mammals is based on building a mental representation of their environment---a cognitive map. However, both the nature of this cognitive map and its underpinning in neural structures and activity remains vague. A key…