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Complex diseases can be modeled as damage to intracellular networks that results in abnormal cell behaviors. Network-based dynamic models such as Boolean models have been employed to model a variety of biological systems including those…

生物物理 · 物理学 2016-12-30 Gang Yang , Colin Campbell , Réka Albert

Maintaining the ability to fire sparsely is crucial for information encoding in neural networks. Additionally, spiking homeostasis is vital for spiking neural networks with changing numbers of weights and neurons. We discuss a range of…

神经与进化计算 · 计算机科学 2019-10-02 Katarzyna Kozdon , Peter Bentley

We study a mechanism of activity sustaining on networks inspired by a well-known model of neuronal dynamics. Our primary focus is the emergence of self-sustaining collective activity patterns, where no single node can stay active by itself,…

物理与社会 · 物理学 2017-12-27 A. E. Allahverdyan , G. Ver Steeg , A. Galstyan

Deep feedforward and recurrent rate-based neural networks have become successful functional models of the brain, but they neglect obvious biological details such as spikes and Dale's law. Here we argue that these details are crucial in…

神经元与认知 · 定量生物学 2023-12-29 William F. Podlaski , Christian K. Machens

The mechanisms responsible for contention of activity in systems represented by networks are crucial in various phenomena, as in diseases such as epilepsy that affects the neuronal networks, and for information dissemination in social…

生物物理 · 物理学 2013-02-20 Diego R. Amancio , Osvaldo N. Oliveira , Luciano da F. Costa

Starting from a spectral expansion of the Fokker-Plank equation for the membrane potential density in a network of spiking neurons, a low-dimensional dynamics of the collective firing rate is derived. As a result a $n$-order ordinary…

神经元与认知 · 定量生物学 2016-09-29 Maurizio Mattia

Neural network dynamics emerge from the interaction of spiking cells. One way to formulate the problem is through a theoretical framework inspired by ideas coming from statistical physics, the so-called mean-field theory. In this document,…

偏微分方程分析 · 数学 2020-11-11 Grégory Dumont , Pierre Gabriel

We study the spike statistics of neurons in a network with dynamically balanced excitation and inhibition. Our model, intended to represent a generic cortical column, comprises randomly connected excitatory and inhibitory leaky…

神经元与认知 · 定量生物学 2007-05-23 Alexander Lerchner , Cristina Ursta , John Hertz , Mandana Ahmadi , Pauline Ruffiot

Brain network is remarkably cost-efficient while the fundamental physical and dynamical mechanisms underlying its economical optimization in network structure and activity are not clear. Here we study intricate cost-efficient interplay…

生物物理 · 物理学 2021-06-21 Junhao Liang , Sheng-Jun Wang , Changsong Zhou

A synfire chain is a network that can generate repeated spike patterns with millisecond precision. Although synfire chains with only one activity propagation mode have been intensively analyzed with several neuron models, those with several…

神经元与认知 · 定量生物学 2009-11-13 Kazuya Ishibashi , Kosuke Hamaguchi , Masato Okada

The steady-state firing rate and firing-rate response of the leaky and exponential integrate-and-fire models receiving synaptic shot noise with excitatory and inhibitory reversal potentials is examined. For the particular case where the…

神经元与认知 · 定量生物学 2024-03-13 Magnus J E Richardson

The ability to understand and eventually predict the emergence of information and activation cascades in social networks is core to complex socio-technical systems research. However, the complexity of social interactions makes this a…

物理与社会 · 物理学 2015-06-16 Pablo Piedrahíta , Javier Borge-Holthoefer , Yamir Moreno , Alex Arenas

Electrical coupling between neurons is broadly present across brain areas and is typically assumed to synchronize network activity. However, intrinsic properties of the coupled cells can complicate this simple picture. Many cell types with…

适应与自组织系统 · 物理学 2018-01-19 Thomas Chartrand , Mark S. Goldman , Timothy J. Lewis

We show that in model neuronal cultures, where the probability of interneuronal connection formation decreases exponentially with increasing distance between the neurons, there exists a small number of spatial nucleation centers of a…

神经元与认知 · 定量生物学 2018-11-09 A. V. Paraskevov , D. K. Zendrikov

We address the problem of identifying functional interactions among stochastic neurons with variable-length memory from their spiking activity. The neuronal network is modeled by a stochastic system of interacting point processes with…

应用统计 · 统计学 2025-07-01 Ricardo F. Ferreira , Matheus E. Pacola , Vitor G. Schiavone , Rodrigo F. O. Pena

The combination of new recording techniques in neuroscience and powerful inference methods recently held the promise to recover useful effective models, at the single neuron or network level, directly from observed data. The value of a…

神经元与认知 · 定量生物学 2018-04-09 Cristiano Capone , Guido Gigante , Paolo Del Giudice

Nonlinear dynamics of spiking neural networks has recently attracted much interest as an approach to understand possible information processing in the brain and apply it to artificial intelligence. Since information can be processed by…

Confinement is a ubiquitous mechanism in nature, whereby particles feel an attractive force that increases without bound as they separate. A prominent example is color confinement in particle physics, in which baryons and mesons are…

Recent work emphasizes that the maximum entropy principle provides a bridge between statistical mechanics models for collective behavior in neural networks and experiments on networks of real neurons. Most of this work has focused on…

神经元与认知 · 定量生物学 2015-06-05 Gasper Tkacik , Olivier Marre , Thierry Mora , Dario Amodei , Michael J. Berry , William Bialek

Experimental characterization of neuronal dynamics involves recording both of spontaneous activity patterns and of responses to transient and sustained inputs. While much theoretical attention has been devoted to the spontaneous activity of…

神经元与认知 · 定量生物学 2020-07-24 Jonathan Rubin , Justyna Signerska-Rynkowska , Jonathan D. Touboul