相关论文: Optimal evaluation of single-molecule force spectr…
This paper is based on lectures presented to mathematical physicists and attempts to provide an overview of the present status of the Standard Model, its experimental tests, phenomenological and experimental motivations for going beyond the…
Development of several alternative mathematical models for the biological system in question and discrimination between such models using experimental data is the best way to robust conclusions. Models which challenge existing theories are…
The status of precision electroweak data, tests of the standard model, determination of its parameters, and constraints on new physics, are surveyed.
One of the most intriguing results of single molecule experiments on proteins and nucleic acids is the discovery of functional heterogeneity: the observation that complex cellular machines exhibit multiple, biologically active…
Electroweak precision tests of the Standard Model of the fundamental interactions are reviewed ranging from the lowest to the highest energy experiments. Results from global fits are presented with particular emphasis on the extraction of…
In recent years, there has been discussion in the literature regarding methods of estimating the magnitude of the minimum principal stress from subsurface fracture injection tests, commonly called Diagnostic Fracture Injection Tests…
Recent developments of microscopic mechanical experiments allow the manipulation of individual polymer molecules in two main ways: \textit{uniform} stretching by external forces and \textit{non-uniform} stretching by external fields. Many…
Single-molecule force spectroscopy has proven to be a powerful tool for studying the kinetic behavior of biomolecules. Through application of an external force, conformational states with small or transient populations can be stabilized,…
Metastases increase the risk of fracture when affecting the femur. Consequently, clinicians need to know if the patients femur can withstand the stress of daily activities. The current tools used in clinics are not sufficiently precise. A…
Griffith thermodynamic energy balance is employed to analyze cleavage phenomenon from atomic level. Results show that the cleavage toughness, the strain energy release rate, and the surface energy can be defined by the bond strength (the…
In the present paper, a fiber bundle model in (1+1)-dimensions that simulates the rupture process of a fibrous material pulled by an uniaxial force F is analyzed. In this model the load of a broken fiber is shifted in equal portions onto…
We show how neutrino data can be used in order to constrain the free parameters of possible extensions to the standard model of elementary particles (SM). For definiteness, we focus in the recently proposed unparticle scenario. We show that…
I review single-molecule experiments (SME) in biological physics. Recent technological developments have provided the tools to design and build scientific instruments of high enough sensitivity and precision to manipulate and visualize…
Forced detachment of a single polymer chain, strongly-adsorbed on a solid substrate, is investigated by two complementary methods: a coarse-grained analytical dynamical model, based on the Onsager stochastic equation, and Molecular Dynamics…
This work proposes a novel theoretical framework of robust limit analysis i.e. the computation of limit loads of structures in presence of uncertainties using limit analysis and robust optimization theories. We first derive generic robust…
A means to extract the fine-structure constant $\alpha$ from precision spectroscopic data on one-electron ions is presented. We show that in an appropriately weighted difference of the bound-electron $g$ factor and the ground state energy,…
The supersymmetric standard model with supergravity-inspired soft breaking terms predicts a rich pectrum of sparticles to be discovered at the SSC, LHC and NLC. Because there are more supersymmetric particles than unknown parameters, one…
Microbond tests composed of single fibre and matrix droplet are often used to determine the properties of fibre reinforced composites. Interfacial shear strength is quantified by the maximum pull-out force assuming a uniform stress…
One-dimensional model for study of sub--femtosecond experiment with metal surface is put forward. The important features of the system, such as the pseudopotential for electron motion in the metal bulk, abrupt decrease of the normal to the…
We review statistical-mechanical theories of single-molecule micromanipulation experiments on nucleic acids. First, models for describing polymer elasticity are introduced. We then review how these models are used to interpret…