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Natural supports of information are given by random copolymers such as DNA or RNA where information is coded in the sequence of covalent bonds. At the molecular scale, the stochastic growth of a single copolymer with or without a template…

生物大分子 · 定量生物学 2016-04-12 Pierre Gaspard

Ecological systems comprise an astonishing diversity of species that cooperate or compete with each other forming complex mutual dependencies. The minimum requirements to maintain a large species diversity on long time scales are in general…

种群与进化 · 定量生物学 2012-09-10 Joachim Mathiesen , Namiko Mitarai , Kim Sneppen , Ala Trusina

Natural language free-text explanation generation is an efficient approach to train explainable language processing models for commonsense-knowledge-requiring tasks. The most predominant form of these models is the explain-then-predict…

计算与语言 · 计算机科学 2021-10-06 Myeongjun Jang , Thomas Lukasiewicz

Even though deep neural models have achieved superhuman performance on many popular benchmarks, they have failed to generalize to OOD or adversarial datasets. Conventional approaches aimed at increasing robustness include developing…

机器学习 · 计算机科学 2022-03-15 Swaroop Mishra , Anjana Arunkumar

Due to its longevity and enormous information density, DNA is an attractive medium for archival data storage. Thanks to rapid technological advances, DNA storage is becoming practically feasible, as demonstrated by a number of experimental…

信息论 · 计算机科学 2022-11-11 Ilan Shomorony , Reinhard Heckel

Whether the media faithfully communicate scientific information has long been a core issue to the science community. Automatically identifying paraphrased scientific findings could enable large-scale tracking and analysis of information…

计算与语言 · 计算机科学 2022-10-25 Dustin Wright , Jiaxin Pei , David Jurgens , Isabelle Augenstein

Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…

定量方法 · 定量生物学 2026-05-20 Antoine Diez , Jean Feydy

Large language models (LLMs) are increasingly expected to function as collaborative partners, engaging in back-and-forth dialogue to solve complex, ambiguous problems. However, current LLMs often falter in real-world settings, defaulting to…

人工智能 · 计算机科学 2025-07-30 Tenghao Huang , Sihao Chen , Muhao Chen , Jonathan May , Longqi Yang , Mengting Wan , Pei Zhou

Open-ended question answering requires models to find appropriate evidence to form wellreasoned, comprehensive and helpful answers. In practical applications, models also need to engage in extended discussions on potential scenarios closely…

计算与语言 · 计算机科学 2024-12-17 Mingxu Tao , Dongyan Zhao , Yansong Feng

The rise of multicellularity in the early evolution of life represents a major challenge for evolutionary biology. Guidance for finding answers has emerged from disparate fields, from phylogenetics to modelling and synthetic biology, but…

种群与进化 · 定量生物学 2015-11-09 Salva Duran-Nebreda , Adriano Bonforti , Raul Montañez , Sergi Valverde , Ricard Solé

Empirical evidence suggesting that living systems might operate in the vicinity of critical points, at the borderline between order and disorder, has proliferated in recent years, with examples ranging from spontaneous brain activity to…

Let $\theta_0,\theta_1 \in \mathbb{R}^d$ be the population risk minimizers associated to some loss $\ell:\mathbb{R}^d\times \mathcal{Z}\to\mathbb{R}$ and two distributions $\mathbb{P}_0,\mathbb{P}_1$ on $\mathcal{Z}$. The models…

统计理论 · 数学 2021-07-13 Dmitrii M. Ostrovskii , Mohamed Ndaoud , Adel Javanmard , Meisam Razaviyayn

We assume that the state of a number of nodes in a network could be investigated if necessary, and study what configuration of those nodes could facilitate a better solution for the diffusion-source-localization (DSL) problem. In…

社会与信息网络 · 计算机科学 2022-05-20 Yang Liu , Xiaoqi Wang , Xi Wang , Zhen Wang , Jürgen Kurths

Prototypical networks aim to build intrinsically explainable models based on the linear summation of concepts. Concepts are coherent entities that we, as humans, can recognize and associate with a certain object or entity. However,…

计算机视觉与模式识别 · 计算机科学 2024-12-17 Hugues Turbé , Mina Bjelogrlic , Gianmarco Mengaldo , Christian Lovis

Large language models (LLMs) make it plausible to build systems that improve through self-evolving loops, but many existing proposals are better understood as self-play and often plateau quickly. A central failure mode is that the loop…

机器学习 · 计算机科学 2026-05-19 Wei Liu , Siya Qi , Yali Du , Yulan He

Protein structure prediction has been a grand challenge for over 50 years, owing to its broad scientific and application interests. There are two primary types of modeling algorithms, template-free modeling and template-based modeling. The…

生物物理 · 物理学 2021-06-01 Liangzhen Zheng , Haidong Lan , Tao Shen , Jiaxiang Wu , Sheng Wang , Wei Liu , Junzhou Huang

The support recovery problem consists of determining a sparse subset of a set of variables that is relevant in generating a set of observations, and arises in a diverse range of settings such as compressive sensing, and subset selection in…

信息论 · 计算机科学 2016-08-31 Jonathan Scarlett , Volkan Cevher

According to the "hard-steps" model, the origin of humanity required "successful passage through a number of intermediate steps" (so-called "hard" or "critical" steps) that were intrinsically improbable with respect to the total time…

种群与进化 · 定量生物学 2025-02-18 Daniel B. Mills , Jennifer L. Macalady , Adam Frank , Jason T. Wright

The rapid spread of misinformation on online platforms undermines trust among individuals and hinders informed decision making. This paper shows an explainable and computationally efficient pipeline to detect misinformation using…

计算与语言 · 计算机科学 2025-10-23 Jainee Patel , Chintan Bhatt , Himani Trivedi , Thanh Thi Nguyen

Speciation is fundamental to the huge diversity of life on Earth. Evidence suggests reproductive isolation arises most commonly in allopatry with a higher speciation rate in small populations. Current theory does not address this dependence…

种群与进化 · 定量生物学 2015-03-27 Bhavin S. Khatri , Richard A. Goldstein