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Cancer is a complex disease that is characterized by uncontrolled growth and division of cells. It involves a complex interplay between genetic and environmental factors that lead to the initiation and progression of tumors. Recent advances…

生物大分子 · 定量生物学 2025-02-07 Reza Bozorgpour

Visual pre-training with large-scale real-world data has made great progress in recent years, showing great potential in robot learning with pixel observations. However, the recipes of visual pre-training for robot manipulation tasks are…

机器人学 · 计算机科学 2023-08-08 Ya Jing , Xuelin Zhu , Xingbin Liu , Qie Sima , Taozheng Yang , Yunhai Feng , Tao Kong

RNA function is deeply intertwined with its conformational dynamics. In this review, we survey recent advances in the use of atomistic molecular dynamics simulations to characterize RNA dynamics in diverse contexts, including isolated…

化学物理 · 物理学 2026-03-06 Olivier Languin-Cattoën , Giovanni Bussi

Autonomy in robotic surgery is very challenging in unstructured environments, especially when interacting with deformable soft tissues. The main difficulty is to generate model-based control methods that account for deformation dynamics…

机器人学 · 计算机科学 2021-05-03 Fei Liu , Zihan Li , Yunhai Han , Jingpei Lu , Florian Richter , Michael C. Yip

Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which…

生物物理 · 物理学 2008-03-07 Debashish Chowdhury

Photo-induced processes are fundamental in nature, but accurate simulations are seriously limited by the cost of the underlying quantum chemical calculations, hampering their application for long time scales. Here we introduce a method…

Finding informative low-dimensional descriptions of high-dimensional simulation data (like the ones arising in molecular dynamics or kinetic Monte Carlo simulations of physical and chemical processes) is crucial to understanding physical…

Simulations at the atomic scale provide a direct and effective way to understand the mechanical properties of materials. In the regime of classical mechanics, simulations for the thermodynamic properties of metals and alloys can be done by…

计算物理 · 物理学 2019-11-05 Ka-Ming Tam , Nicholas Walker , Samuel Kellar , Mark Jarrell

Molecular dynamics (MD) simulations employing classical force fields constitute the cornerstone of contemporary atomistic modeling in chemistry, biology, and materials science. However, the predictive power of these simulations is only as…

化学物理 · 物理学 2018-09-26 Stefan Chmiela , Huziel E. Sauceda , Klaus-Robert Müller , Alexandre Tkatchenko

Many aspects of the study of protein folding and dynamics have been affected by the recent advances in machine learning. Methods for the prediction of protein structures from their sequences are now heavily based on machine learning tools.…

生物物理 · 物理学 2019-11-25 Frank Noé , Gianni De Fabritiis , Cecilia Clementi

This study employed an artificial intelligence-enhanced molecular simulation framework to enable efficient Path Integral Molecular Dynamics (PIMD) simulations. Owing to its modular architecture and high-throughput capabilities, the…

化学物理 · 物理学 2025-04-01 Cheng Fan , Maodong Li , Sihao Yuan , Zhaoxin Xie , Dechin Chen , Yi Isaac Yang , Yi Qin Gao

Protein adsorption/desorption upon nanoparticle surfaces is an important process to understand for developing new nanotechnology involving biomaterials, while atomistic picture of the process and its coupling with protein conformational…

生物物理 · 物理学 2017-11-10 Huifang Xiao , Bin Huang , Ge Yao , Wenbin Kang , Sheng Gong , Hai Pan , Yi Cao , Jun Wang , Jian Zhang , Wei Wang

This paper presents modeling and simulation of a spined quadruped robot. Extended literature survey is employed and spine joints researches of the quadruped robots are classified. Most of the researchers execute simplified quadruped robot…

机器人学 · 计算机科学 2022-03-21 Omer Kemal Adak , Beste Bahceci , Kemalettin Erbatur

The molecular simulations solve the equation of motion of molecular systems, making 3D shapes of molecules four-dimensional by adding the time coordinate. These methods have a great potential in drug discovery because they can realistically…

生物大分子 · 定量生物学 2023-01-19 Dalibor Trapl , Vojtěch Spiwok

In recent years, machine learning interatomic potentials (MLIPs) have attracted significant attention as a method that enables large-scale, long-time atomistic simulations while maintaining accuracy comparable to electronic structure…

材料科学 · 物理学 2025-03-27 Yuta Yoshimoto , Naoki Matsumura , Yuto Iwasaki , Hiroshi Nakao , Yasufumi Sakai

Warm dense matter systems created in the laboratory are highly dynamical. In such cases electron dynamics is often needed to accurately simulate the evolution and properties of the system. Large systems force one to make simple…

量子气体 · 物理学 2014-08-13 Paul E. Grabowski

Interatomic potentials are essential for driving molecular dynamics (MD) simulations, directly impacting the reliability of predictions regarding the physical and chemical properties of materials. In recent years, machine-learned potentials…

材料科学 · 物理学 2025-03-20 Penghua Ying , Cheng Qian , Rui Zhao , Yanzhou Wang , Feng Ding , Shunda Chen , Zheyong Fan

Accurate physical modeling with 3D-printing techniques could lead to new approaches to study structure and dynamics of biological systems complementing computational methods. Computational biology has become an important part of research…

其他计算机科学 · 计算机科学 2015-07-14 Promita Chakraborty

Fast and light-weight methods for animating 3D characters are desirable in various applications such as computer games. We present a learning-based approach to enhance skinning-based animations of 3D characters with vivid secondary motion…

计算机视觉与模式识别 · 计算机科学 2021-04-13 Mianlun Zheng , Yi Zhou , Duygu Ceylan , Jernej Barbič

Molecular dynamics simulations are an essential tool in understanding protein structure, dynamics, and function at the atomic level. However, preparing high quality input files for MD simulations can be a time consuming and error prone…

计算与语言 · 计算机科学 2025-07-11 Achuth Chandrasekhar , Amir Barati Farimani