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The simultaneous analysis of many statistical tests is ubiquitous in applications. Perhaps the most popular error rate used for avoiding type one error inflation is the false discovery rate (FDR). However, most theoretical and software…

统计计算 · 统计学 2019-04-04 Guillermo Durand , Florian Junge , Sebastian Döhler , Etienne Roquain

False discovery rate (FDR) control is a popular approach for maintaining the integrity of statistical analyses, especially in high-dimensional data settings, where multiple comparisons increase the risk of false positives. FDR control has…

信号处理 · 电气工程与系统科学 2026-03-03 Fabian Scheidt , Jasin Machkour , Michael Muma

The genetic basis of multiple phenotypes such as gene expression, metabolite levels, or imaging features is often investigated by testing a large collection of hypotheses, probing the existence of association between each of the traits and…

应用统计 · 统计学 2015-04-06 Christine Peterson , Marina Bogomolov , Yoav Benjamini , Chiara Sabatti

Identifying signals that replicate across multiple studies is essential for establishing robust scientific evidence, yet existing methods for high-dimensional replicability analysis either rely on restrictive modeling assumptions, are…

统计方法学 · 统计学 2026-03-05 Haochen Lei , Yan Li , Hongyuan Cao

This paper revisits the following open question in simultaneous testing of multivariate normal means against two-sided alternatives: Can the method of Benjamini and Hochberg (BH, 1995) control the false discovery rate (FDR) without imposing…

统计理论 · 数学 2023-04-12 Sanat K. Sarkar

Controlling False Discovery Rate (FDR) while leveraging the side information of multiple hypothesis testing is an emerging research topic in modern data science. Existing methods rely on the test-level covariates while ignoring metrics…

机器学习 · 统计学 2022-10-10 Lin Qiu , Nils Murrugarra-Llerena , Vítor Silva , Lin Lin , Vernon M. Chinchilli

Most link prediction methods return estimates of the connection probability of missing edges in a graph. Such output can be used to rank the missing edges from most to least likely to be a true edge, but does not directly provide a…

统计方法学 · 统计学 2024-03-26 Ariane Marandon

We provide the first differentially private algorithms for controlling the false discovery rate (FDR) in multiple hypothesis testing, with essentially no loss in power under certain conditions. Our general approach is to adapt a well-known…

统计理论 · 数学 2015-11-13 Cynthia Dwork , Weijie Su , Li Zhang

Multiple testing is a fundamental problem in high-dimensional statistical inference. Although many methods have been proposed to control false discoveries, it is still a challenging task when the tests are correlated to each other. To…

统计理论 · 数学 2022-07-06 Meng Mei , Yuan Jiang

E-values have gained attention as potential alternatives to p-values as measures of uncertainty, significance and evidence. In brief, e-values are realized by random variables with expectation at most one under the null; examples include…

统计理论 · 数学 2021-12-16 Ruodu Wang , Aaditya Ramdas

In many fields of science, we observe a response variable together with a large number of potential explanatory variables, and would like to be able to discover which variables are truly associated with the response. At the same time, we…

统计方法学 · 统计学 2015-10-15 Rina Foygel Barber , Emmanuel J. Candès

We develop a new class of distribution--free multiple testing rules for false discovery rate (FDR) control under general dependence. A key element in our proposal is a symmetrized data aggregation (SDA) approach to incorporating the…

统计方法学 · 统计学 2021-05-27 Lilun Du , Xu Guo , Wenguang Sun , Changliang Zou

In many large scale multiple testing applications, the hypotheses often have a known graphical structure, such as gene ontology in gene expression data. Exploiting this graphical structure in multiple testing procedures can improve power as…

统计方法学 · 统计学 2018-12-04 Wenge Guo , Gavin Lynch , Joseph P. Romano

The most popular multiple testing procedures are stepwise procedures based on $P$-values for individual test statistics. Included among these are the false discovery rate (FDR) controlling procedures of Benjamini--Hochberg [J. Roy. Statist.…

统计理论 · 数学 2009-06-18 Arthur Cohen , Harold B. Sackrowitz , Minya Xu

Simultaneously finding multiple influential variables and controlling the false discovery rate (FDR) for linear regression models is a fundamental problem. We here propose the Gaussian Mirror (GM) method, which creates for each predictor…

统计方法学 · 统计学 2021-03-22 Xin Xing , Zhigen Zhao , Jun S. Liu

When testing multiple hypotheses, a suitable error rate should be controlled even in exploratory trials. Conventional methods to control the False Discovery Rate (FDR) assume that all p-values are available at the time point of test…

统计方法学 · 统计学 2021-12-21 Sonja Zehetmayer , Martin Posch , Franz Koenig

How to weigh the Benjamini-Hochberg procedure? In the context of multiple hypothesis testing, we propose a new step-wise procedure that controls the false discovery rate (FDR) and we prove it to be more powerful than any weighted…

统计理论 · 数学 2009-07-13 Etienne Roquain , Mark Van De Wiel

Online controlled experiments (also known as A/B Testing) have been viewed as a golden standard for large data-driven companies since the last few decades. The most common A/B testing framework adopted by many companies use "average…

统计方法学 · 统计学 2021-10-15 Yihan Bao , Shichao Han , Yong Wang

The steep rise in availability and usage of high-throughput technologies in biology brought with it a clear need for methods to control the False Discovery Rate (FDR) in multiple tests. Benjamini and Hochberg (BH) introduced in 1995 a…

统计方法学 · 统计学 2011-08-11 Amit Zeisel , Or Zuk , Eytan Domany

In many scientific applications, hypotheses are generated and tested continuously in a stream. We develop a framework for improving online multiple testing procedures with false discovery rate (FDR) control under arbitrary dependence. Our…

统计方法学 · 统计学 2026-03-27 Ziyu Xu , Lasse Fischer , Aaditya Ramdas