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Hybrid quantum mechanics / molecular mechanics (QM/MM) models successfully describe the properties of biological macromolecules. However, most QM/MM methodologies are constrained to unrealistic gas phase models, thus limiting their…

化学物理 · 物理学 2022-11-08 Simone Bonfrate , Nicolas Ferré , Miquel , Huix-Rotllant

We present a geometric Particle-in-Cell (PIC) algorithm on two-dimensional (2D) unstructured meshes for studying electrostatic perturbations in magnetized plasmas. In this method, ions are treated as fully kinetic particles, and electrons…

等离子体物理 · 物理学 2021-08-11 Zhenyu Wang , Hong Qin , Benjamin Sturdevant , C. S. Chang

Parameter identification for electrochemical battery models has always been challenging due to the multitude of parameters involved, most of which cannot be directly measured. This paper evaluates the efficiency and optimality of three…

系统与控制 · 电气工程与系统科学 2025-11-04 Feng Guo , Luis D. Couto , Guillaume Thenaisie

The Particle-Particle-Particle-Mesh algorithm elegantly extends the standard Particle-In-Cell scheme by direct summation of interaction that happens over distances below or around mesh size. Generally, this allows for a more accurate…

计算物理 · 物理学 2021-04-19 Tim Wyssling , Andreas Adelmann

A novel design procedure for practical hierarchical distribution matchers (HiDMs) in probabilistically shaped constellation systems is presented. The proposed approach enables the determination of optimal parameters for any target…

信号处理 · 电气工程与系统科学 2026-01-26 Pantea Nadimi Goki , Luca Potì

We introduce and employ two QM:QM schemes (a quantum mechanical method embedded into another quantum mechanical method) and report their performance for the X23 set of molecular crystals. We furthermore present the theory to calculate the…

化学物理 · 物理学 2018-10-17 Oleksandr A. Loboda , Grygoriy A. Dolgonos , A. Daniel Boese

We develop interacting particle algorithms for learning latent variable models with energy-based priors. To do so, we leverage recent developments in particle-based methods for solving maximum marginal likelihood estimation (MMLE) problems.…

机器学习 · 统计学 2025-10-15 Joanna Marks , Tim Y. J. Wang , O. Deniz Akyildiz

Dielectrically confined Coulomb systems are widely employed in molecular dynamics (MD) simulations. Despite extensive efforts in developing efficient and accurate algorithms for these systems, rigorous and accurate error estimates, which…

数值分析 · 数学 2025-03-25 Xuanzhao Gao , Qi Zhou , Zecheng Gan , Jiuyang Liang

Central idea: To obtain the interaction potential using the inverse scattering method, we have employed the Physics-Informed Machine Learning (PIML) approach. In this framework, the machine learning algorithm is guided by the underlying…

We introduce affordable computational strategies for calculating orbital and pair-orbital energies in atomic and molecular systems. Our methods are based on the pair Coupled Cluster Doubles (pCCD) ansatz and its orbital-optimized variant.…

The presented article contains a 3D mesh generation routine optimized with the Metropolis algorithm. The procedure enables to produce meshes of a prescribed volume V_0 of elements. The finite volume meshes are used with the Finite Element…

计算几何 · 计算机科学 2011-03-31 Ilona D. Kosinska

Computing many-body ground state energies and resolving electronic structure calculations are fundamental problems for fields such as quantum chemistry or condensed matter. Several quantum computing algorithms that address these problems…

量子物理 · 物理学 2023-01-12 Karen J. Morenz Korol , Kenny Choo , Antonio Mezzacapo

An exact arithmetic, memory efficient direct solution method for finite element method (FEM) computations is outlined. Unlike conventional black-box or low-rank direct solvers that are opaque to the underlying physical problem, the proposed…

计算工程、金融与科学 · 计算机科学 2020-02-13 Javad Moshfegh , Marinos N. Vouvakis

Accounting for geometry-induced changes in the electronic distribution in molecular simulation is important for capturing effects such as charge flow, charge anisotropy and polarization. Multipolar force fields have demonstrated their…

化学物理 · 物理学 2022-07-01 Eric D. Boittier , Mike Devereux , Markus Meuwly

Maximum likelihood estimation (MLE) of latent variable models is often recast as the minimization of a free energy functional over an extended space of parameters and probability distributions. This perspective was recently combined with…

机器学习 · 计算机科学 2024-06-05 Jen Ning Lim , Juan Kuntz , Samuel Power , Adam M. Johansen

The information-encoding molecules RNA and DNA form a combinatorially large set of secondary structures through nucleic acid base pairing. Thermodynamic prediction algorithms predict favoured, or minimum free energy (MFE), secondary…

数据结构与算法 · 计算机科学 2024-07-16 Ahmed Shalaby , Damien Woods

A novel electromagnetic particle-in-cell algorithm has been developed for fully kinetic plasma simulations on unstructured (irregular) meshes in complex body-of-revolution geometries. The algorithm, implemented in the BORPIC++ code,…

数值分析 · 数学 2024-05-16 Dong-Yeop Na , Fernando L. Teixeira , Yuri A. Omelchenko

Studying the propagation of uncertainties in a nonlinear dynamical system usually involves generating a set of samples in the stochastic parameter space and then repeated simulations with different sampled parameters. The main difficulty…

数值分析 · 数学 2017-09-19 Nan Jiang , Michael Schneier

The particle-particle random phase approximation (pp-RPA) has been shown to be capable of describing double, Rydberg, and charge transfer excitations, for which the conventional time-dependent density functional theory (TDDFT) might not be…

计算物理 · 物理学 2017-04-26 Jianfeng Lu , Haizhao Yang

Molecule synthesis through machine learning is one of the fundamental problems in drug discovery. Current data-driven strategies employ one-step retrosynthesis models and search algorithms to predict synthetic routes in a top-bottom manner.…

机器学习 · 计算机科学 2024-06-05 Songtao Liu , Hanjun Dai , Yue Zhao , Peng Liu