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Bioinformatics research is characterized by voluminous and incremental datasets and complex data analytics methods. The machine learning methods used in bioinformatics are iterative and parallel. These methods can be scaled to handle big…

计算工程、金融与科学 · 计算机科学 2015-06-17 Hirak Kashyap , Hasin Afzal Ahmed , Nazrul Hoque , Swarup Roy , Dhruba Kumar Bhattacharyya

Although the use of metric fluents is fundamental to many practical planning problems, the study of heuristics to support fully automated planners working with these fluents remains relatively unexplored. The most widely used heuristic is…

人工智能 · 计算机科学 2014-02-05 Amanda Jane Coles , Andrew Ian Coles , Maria Fox , Derek Long

An applied problem facing all areas of data science is harmonizing data sources. Joining data from multiple origins with unmapped and only partially overlapping features is a prerequisite to developing and testing robust, generalizable…

Heuristic optimisation algorithms explore the search space by sampling solutions, evaluating their fitness, and biasing the search in the direction of promising solutions. However, in many cases, this fitness function involves executing…

神经与进化计算 · 计算机科学 2024-10-07 Pablo S. Naharro , Pablo Toharia , Antonio LaTorre , José-María Peña

Data analytics often involves hypothetical reasoning: repeatedly modifying the data and observing the induced effect on the computation result of a data-centric application. Previous work has shown that fine-grained data provenance can help…

数据库 · 计算机科学 2020-07-13 Daniel Deutch , Yuval Moskovitch , Noam Rinetzky

Fixed parameter tractable algorithms for bounded treewidth are known to exist for a wide class of graph optimization problems. While most research in this area has been focused on exact algorithms, it is hard to find decompositions of…

数据结构与算法 · 计算机科学 2016-10-05 Thomas Bosman

Hierarchical models with gamma hyperpriors provide a flexible, sparse-promoting framework to bridge $L^1$ and $L^2$ regularizations in Bayesian formulations to inverse problems. Despite the Bayesian motivation for these models, existing…

统计方法学 · 统计学 2021-11-30 Shiv Agrawal , Hwanwoo Kim , Daniel Sanz-Alonso , Alexander Strang

This paper provides experimental experiences on two local search hybridized genetic algorithms in solving the uncapacitated examination timetabling problem. The proposed two hybrid algorithms use partition and priority based solution…

神经与进化计算 · 计算机科学 2023-06-02 Ayse Aslan

Metaheuristics are stochastic optimization algorithms that mimic natural processes to find optimal solutions to complex problems. The success of metaheuristics largely depends on the ability to effectively explore and exploit the search…

神经与进化计算 · 计算机科学 2024-11-26 Salar Farahmand-Tabar

We tackle modelling and inference for variable selection in regression problems with many predictors and many responses. We focus on detecting hotspots, i.e., predictors associated with several responses. Such a task is critical in…

Relying on either deep models or physical models are two mainstream approaches for solving inverse sample reconstruction problems in programmable illumination computational microscopy. Solutions based on physical models possess strong…

图像与视频处理 · 电气工程与系统科学 2024-03-21 Ruiqing Sun , Delong Yang , Shaohui Zhang , Qun Hao

This paper presents a non-parametric classification technique for identifying a candidate bi-allelic genetic marker set that best describes disease susceptibility in gene-gene interaction studies. The developed technique functions by…

This paper presents a generic technique for improving hybrid algorithms through the discovery of and tuning of meta-heuristics. The idea is to represent a family of push/pull heuristics that are based upon inserting and removing tasks in a…

编程语言 · 计算机科学 2007-05-23 Yves Caseau , Glenn Silverstein , Francois Laburthe

Over-parameterized models, such as DeepNets and ConvNets, form a class of models that are routinely adopted in a wide variety of applications, and for which Bayesian inference is desirable but extremely challenging. Variational inference…

机器学习 · 统计学 2020-11-24 Simone Rossi , Sebastien Marmin , Maurizio Filippone

This study investigates the potential of hybrid metaheuristic algorithms to enhance the training of Probabilistic Neural Networks (PNNs) by leveraging the complementary strengths of multiple optimisation strategies. Traditional learning…

神经与进化计算 · 计算机科学 2025-04-16 Piotr A. Kowalski , Szymon Kucharczyk , Jacek Mańdziuk

Genetic variants identified to date by genome-wide association studies only explain a small fraction of total heritability. Gene-by-gene interaction is one important potential source of unexplained heritability. In the first part of this…

统计方法学 · 统计学 2016-05-10 Chen Lu

Surrogate-based optimization, nature-inspired metaheuristics, and hybrid combinations have become state of the art in algorithm design for solving real-world optimization problems. Still, it is difficult for practitioners to get an overview…

神经与进化计算 · 计算机科学 2021-01-26 Jörg Stork , A. E. Eiben , Thomas Bartz-Beielstein

Citation recommendation systems aim to recommend citations for either a complete paper or a small portion of text called a citation context. The process of recommending citations for citation contexts is called local citation recommendation…

信息检索 · 计算机科学 2020-06-02 Michael Färber , Ashwath Sampath

We consider the problem of detecting and estimating the strength of association between a trait of interest and alleles or haplotypes in a small genomic region (e.g. a gene or a gene complex), when no direct information on that region is…

应用统计 · 统计学 2008-04-11 Rodrigo Labouriau , Poul Sørensen , Helle R. Juul-Madsen

Recent studies in using deep learning to solve routing problems focus on construction heuristics, the solutions of which are still far from optimality. Improvement heuristics have great potential to narrow this gap by iteratively refining a…

人工智能 · 计算机科学 2020-05-12 Yaoxin Wu , Wen Song , Zhiguang Cao , Jie Zhang , Andrew Lim