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The theory of monotone dynamical systems has been found very useful in the modeling of some gene, protein, and signaling networks. In monotone systems, every net feedback loop is positive. On the other hand, negative feedback loops are…

动力系统 · 数学 2009-11-13 Liming Wang , Eduardo Sontag

Biological molecular machines are bifunctional enzymes that catalyze two processes: one donating free energy and the other accepting it. Recent studies show that most protein enzymes have rich stochastic dynamics of transitions between the…

生物物理 · 物理学 2023-02-02 Michal Kurzynski , Przemyslaw Chelminiak

Concurrent presence of inter-cell and intra-cell interferences constitutes a major impediment to reliable downlink transmission in multi-cell multiuser networks. Harnessing such interferences largely hinges on two levels of information…

信息论 · 计算机科学 2016-08-24 Ali Tajer , Xiaodong Wang

The mitogen-activated protein kinase (MAPK) signaling cascade, an evolutionarily conserved motif present in all eukaryotic cells, is involved in coordinating critical cell-fate decisions, regulating protein synthesis, and mediating learning…

亚细胞过程 · 定量生物学 2024-06-11 Tanmay Mitra , Shakti N. Menon , Sitabhra Sinha

The ubiquity of information transmission via molecular communication between cells is comprehensively documented on Earth; this phenomenon might even have played a vital role in the origin(s) and early evolution of life. Motivated by these…

地球与行星天体物理 · 物理学 2024-01-26 Manasvi Lingam

In this paper, we introduce a mathematical approach for system-level analysis and optimization of densely deployed multiple-antenna cellular networks, where low-energy devices are capable of decoding information data and harvesting power…

信息论 · 计算机科学 2016-08-30 Lam Thanh Tu , Marco Di Renzo , Justin P. Coon

Due to the redundant nature of DNA synthesis and sequencing technologies, a basic model for a DNA storage system is a multi-draw "shuffling-sampling" channel. In this model, a random number of noisy copies of each sequence is observed at…

信息论 · 计算机科学 2021-12-06 Kel Levick , Reinhard Heckel , Ilan Shomorony

Where do entangled multiple-qubit systems store information? For information injected into a qubit, this question is nontrivial and interesting since the entanglement delocalizes the information. So far, a common picture is that of a qubit…

量子物理 · 物理学 2019-04-11 Koji Yamaguchi , Naoki Watamura , Masahiro Hotta

Information theory has explained the organization of many biological phenomena, from the physiology of sensory receptive fields to the variability of certain DNA sequence ensembles. Some scholars have proposed that information should…

其他定量生物学 · 定量生物学 2010-10-25 Edward K. Agarwala , Hillel J. Chiel , Peter J. Thomas

Information must take up space, must weigh, and its flux must be limited. Quantum limits on communication and information storage leading to these conclusions are here described. Quantum channel capacity theory is reviewed for both steady…

量子物理 · 物理学 2015-06-26 Jacob D. Bekenstein , Marcelo Schiffer

The methylation of DNA regulates gene expression. On cell division the methylation state of the DNA is typically inherited from parent to daughter cells. While the chemical bond between the methyl group and the DNA is very strong, changes…

种群与进化 · 定量生物学 2012-10-05 Sean P Stromberg

We study the amount of reliable information that can be stored in a DNA-based storage system composed of short DNA molecules. In this regime, Shomorony and Heckel (2022) put forward a conjecture on the scaling of the number of information…

信息论 · 计算机科学 2025-11-19 Ran Tamir , Nir Weinberger , Albert Guillén i Fàbregas

Storage lifetime and capacity are two important factors to characterize the performance of a quantum memory. Here we report the stable trapping of above 200 ions in a cryogenic setup, and demonstrate the combination of the multi-qubit…

量子物理 · 物理学 2023-01-04 R. Yao , W. -Q. Lian , Y. -K. Wu , G. -X. Wang , B. -W. Li , Q. -X. Mei , B. -X. Qi , L. Yao , Z. -C. Zhou , L. He , L. -M. Duan

The utilization of multiple phosphorylation sites in regulating a biological response is ubiquitous in cell signaling. If each site contributes an additional, equivalent binding site, then one consequence of an increase in the number of…

亚细胞过程 · 定量生物学 2009-11-13 Jason W. Locasale

Cells are constantly exposed to fluctuating environmental conditions. External signals are sensed, processed and integrated by cellular signal transduction networks, which translate input signals into specific cellular responses by means of…

分子网络 · 定量生物学 2012-05-29 Pau Rué , Núria Domedel-Puig , Jordi Garcia-Ojalvo , Antonio J. Pons

DNA-based storage is an emerging storage technology that provides high information density and long duration. Due to the physical constraints in the reading and writing processes, error correction in DNA storage poses several interesting…

信息论 · 计算机科学 2023-10-04 Jin Sima , Netanel Raviv , Moshe Schwartz , Jehoshua Bruck

The length distribution of proteins measured in amino acids follows the CoHSI (Conservation of Hartley-Shannon Information) probability distribution. In previous papers we have verified various predictions of this using the Uniprot database…

其他定量生物学 · 定量生物学 2018-10-23 Les Hatton , Gregory Warr

It has been shown that sets of oscillators in a modular network can exhibit a rich variety of metastable chimera states, in which synchronisation and desynchronisation coexist. Independently, under the guise of integrated information…

神经元与认知 · 定量生物学 2016-06-28 Pedro A. M. Mediano , Juan Carlos Farah , Murray Shanahan

Quantum systems are inherently dissipation-less, making them excellent candidates even for classical information processing. We propose to use an array of large-spin quantum magnets for realizing a device which has two modes of operation:…

量子物理 · 物理学 2015-10-29 Ning Jia , Leonardo Banchi , Abolfazl Bayat , Guangjiong Dong , Sougato Bose

Random-access quantum memories may offer computational advantages for quantum computers and networks. In this paper, we advance arrays of solid-state quantum memories towards their usage as random-access quantum memory. We perform quantum…

量子物理 · 物理学 2025-09-16 Markus Teller , Susana Plascencia , Samuele Grandi , Hugues de Riedmatten