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相关论文: False discovery rate control with multivariate $p$…

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In multiple testing several criteria to control for type I errors exist. The false discovery rate, which evaluates the expected proportion of false discoveries among the rejected null hypotheses, has become the standard approach in this…

统计方法学 · 统计学 2023-11-03 Jacobo de Uña-Álvarez

Clustered effects are often encountered in multiple hypothesis testing of spatial signals. In this paper, we propose a new method, termed \textit{two-dimensional spatial multiple testing} (2d-SMT) procedure, to control the false discovery…

统计方法学 · 统计学 2024-08-13 Linsui Deng , Kejun He , Xianyang Zhang

A method is demonstrated for representing the false discovery rate (FDR) in a set of p-values on a quantile-quantile (Q-Q) plot of the p-values. Recognition of this connection between the FDR and the Q-Q plot facilitates both understanding…

统计方法学 · 统计学 2021-09-07 N. W. Galwey

When testing multiple hypotheses, a suitable error rate should be controlled even in exploratory trials. Conventional methods to control the False Discovery Rate (FDR) assume that all p-values are available at the time point of test…

统计方法学 · 统计学 2021-12-21 Sonja Zehetmayer , Martin Posch , Franz Koenig

In the online multiple testing problem, p-values corresponding to different null hypotheses are observed one by one, and the decision of whether or not to reject the current hypothesis must be made immediately, after which the next p-value…

统计方法学 · 统计学 2017-10-03 Aaditya Ramdas , Fanny Yang , Martin J. Wainwright , Michael I. Jordan

We consider the problem of asynchronous online testing, aimed at providing control of the false discovery rate (FDR) during a continual stream of data collection and testing, where each test may be a sequential test that can start and stop…

统计方法学 · 统计学 2020-08-25 Tijana Zrnic , Aaditya Ramdas , Michael I. Jordan

We develop a flexible feature selection framework based on deep neural networks that approximately controls the false discovery rate (FDR), a measure of Type-I error. The method applies to architectures whose first layer is fully connected.…

机器学习 · 统计学 2026-02-10 Kazuma Sawaya

Many multiple testing procedures make use of the p-values from the individual pairs of hypothesis tests, and are valid if the p-value statistics are independent and uniformly distributed under the null hypotheses. However, it has recently…

统计方法学 · 统计学 2011-08-25 Joshua D. Habiger , Edsel A. Pena

Simultaneously finding multiple influential variables and controlling the false discovery rate (FDR) for linear regression models is a fundamental problem. We here propose the Gaussian Mirror (GM) method, which creates for each predictor…

统计方法学 · 统计学 2021-03-22 Xin Xing , Zhigen Zhao , Jun S. Liu

Penalized regression methods are an attractive tool for high-dimensional data analysis, but their widespread adoption has been hampered by the difficulty of applying inferential tools. In particular, the question "How reliable is the…

统计理论 · 数学 2026-05-13 Patrick Breheny

We provide the first differentially private algorithms for controlling the false discovery rate (FDR) in multiple hypothesis testing, with essentially no loss in power under certain conditions. Our general approach is to adapt a well-known…

统计理论 · 数学 2015-11-13 Cynthia Dwork , Weijie Su , Li Zhang

Negative control is a common technique in scientific investigations and broadly refers to the situation where a null effect (''negative result'') is expected. Motivated by a real proteomic dataset, we will present three promising and…

统计方法学 · 统计学 2023-03-21 Zijun Gao , Qingyuan Zhao

Genome-wide association studies (GWAS) have led to the discovery of numerous single nucleotide polymorphisms (SNPs) associated with various phenotypes and complex diseases. However, the identified genetic variants do not fully explain the…

统计方法学 · 统计学 2025-07-09 Dayeon Jung , Yewon Kim , Junyong Park

The effective utilization of structural information in data while ensuring statistical validity poses a significant challenge in false discovery rate (FDR) analyses. Conformal inference provides rigorous theory for grounding complex machine…

统计方法学 · 统计学 2024-06-18 Zinan Zhao , Wenguang Sun

The large bulk of work in multiple testing has focused on specifying procedures that control the false discovery rate (FDR), with relatively less attention being paid to the corresponding Type II error known as the false non-discovery rate…

统计理论 · 数学 2020-05-11 Max Rabinovich , Michael I. Jordan , Martin J. Wainwright

Multiple testing with discrete p-values routinely arises in various scientific endeavors. However, procedures, including the false discovery rate (FDR) controlling Benjamini-Hochberg (BH) procedure, often used in such settings, being…

统计方法学 · 统计学 2019-06-06 Xiongzhi Chen , Sanat K. Sarkar

Controlled variable selection is an important analytical step in various scientific fields, such as brain imaging or genomics. In these high-dimensional data settings, considering too many variables leads to poor models and high costs,…

统计方法学 · 统计学 2023-10-17 Alexandre Blain , Bertrand Thirion , Olivier Grisel , Pierre Neuvial

We consider the problem of multiple hypothesis testing with generic side information: for each hypothesis $H_i$ we observe both a p-value $p_i$ and some predictor $x_i$ encoding contextual information about the hypothesis. For large-scale…

统计方法学 · 统计学 2018-07-26 Lihua Lei , William Fithian

Conventional multiple testing procedures often assume hypotheses for different features are exchangeable. However, in many scientific applications, additional covariate information regarding the patterns of signals and nulls are available.…

统计方法学 · 统计学 2020-06-12 Xianyang Zhang , Jun Chen

This paper explores a connection between empirical Bayes posterior distributions and false discovery rate (FDR) control. In the Gaussian sequence model, this work shows that empirical Bayes-calibrated spike and slab posterior distributions…

统计理论 · 数学 2019-06-18 Ismael Castillo , Etienne Roquain