相关论文: Converting genetic network oscillations into somit…
Many cellular functions are based on the rhythmic organization of biological processes into self-repeating cascades of events. Some of these periodic processes, such as the cell cycles of several species, exhibit conspicuous irregularities…
Nonequilibrium membrane pattern formation is studied using meshless membrane simulation. We consider that molecules bind to either surface of a bilayer membrane and move to the opposite leaflet by flip--flop. When binding does not modify…
Based on a non-equilibrium mechanism for spatial pattern formation we study how position information can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of cells in a developing…
We study the time evolution of a complex scalar field in the symmetry broken phase in the presence of oscillating spacetime metric background. In our (2+1)-dimensional simulations, we show that the spacetime oscillations can excite an…
Constraints in embryonic development are thought to bias the direction of evolution by making some changes less likely, and others more likely, depending on their consequences on ontogeny. Here, we characterize the constraints acting on…
During development of biological organisms, multiple complex structures are formed. In many instances, these structures need to exhibit a high degree of order to be functional, although many of their constituents are intrinsically…
A fundamental task in developmental biology is to identify the mechanisms which drive morphogenesis. In many cases, pattern formation is driven by the positional information determined by both the gradient of maternal factors and hard-wired…
Interacting populations often create complicated spatiotemporal behavior, and understanding it is a basic problem in the dynamics of spatial systems. We study the two-species case by simulations of a host--parasitoid model. In the case of…
First return maps of interspike intervals for biological neurons that generate repetitive bursts of impulses can display stereotyped structures (neuronal signatures). Such structures have been linked to the possibility of multicoding and…
Rhythmogenesis, which is critical for many biological functions, involves a transition to coherent activity through cell-cell communication. In the absence of centralized coordination by specialized cells (pacemakers), competing oscillating…
Axonal growth and guidance at the ventral floor plate is here followed $\textit{in vivo}$ in real time at high resolution by light-sheet microscopy along several hundred micrometers of the zebrafish spinal cord. The recordings show the…
The rheological properties of biological tissues are core to processes such as cancer metastasis, wound healing and embryo development. The emergence of tissue and organ structures during morphogenesis requires the precise formation of…
Based on a recently proposed non-equilibrium mechanism for spatial pattern formation [cond-mat/0312366] we study how morphogenesis can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of…
Notch signaling is an evolutionary conserved cell-cell communication pathway. Besides regulating cell-fate decisions at an individual cell level, Notch signaling coordinates the emergent spatiotemporal patterning in a tissue through…
We demonstrate the emergence of self-organized structures in the course of the relaxation of an initially excited, dissipative and finite chain of interacting particles in a periodic potential towards its many particle equilibrium…
Oscillatory activities are widely observed in specific frequency bands of recorded field potentials in different brain regions, and play critical roles in processing neural information. Understanding the structure of these oscillatory…
We identify a new type of pattern formation in spatially distributed active systems. We simulate one-dimensional two-component systems with predator-prey local interaction and pursuit-evasion taxis between the components. In a sufficiently…
Interactions by mutual excitation in neural populations in human and animal brains create a mesoscopic order parameter that is recorded in brain waves (electroencephalogram, EEG). Spatially and spectrally distributed oscillations are…
Neurons are often connected, spatially and temporally, in phenomenal ways that promote wave propagation. Therefore, it is essential to analyze the emergent spatiotemporal patterns to understand the working mechanism of brain activity,…
Transcriptional activity has been shown to relate to the organization of chromosomes in the eukaryotic nucleus and in the bacterial nucleoid. In particular, highly transcribed genes, RNA polymerases and transcription factors gather into…