种群与进化
The origin of life required the emergence of metabolism, an autocatalytic network of enzymatic reactions that synthesize amino acids, nucleotides and cofactors. At the origin of metabolism there were no enzymes--how did it start? Empirical…
Failing to account for ecological processes such as dispersal and connectivity when modeling distributions can lead to biased inference about environmental drivers and reduced predictive performance. Spatial dynamic occupancy models are…
The Great Filter hypothesis proposes that the emergence of technological societies capable of interstellar travel depends on a small number of exceptionally hard and highly improbable steps. Traditional versions of this hypothesis enumerate…
Spatial environmental variation can either amplify or suppress the fixation of beneficial mutants in structured populations, yet the interplay of ecological factors and spatial structure in determining which outcome occurs remains…
We introduce and discuss a kinetic framework describing the time evolution of the statistical distributions of a population divided into the compartments of susceptible, infectious, recovered, and resistant in the presence of a microbial…
Theoretical ecologists have long leveraged empirical data in various forms to advance ecology. Recently increased volumes and access to ecological data present an expanding set of opportunities for theoreticians to inform model development,…
Identity by descent (IBD) tracts and runs of homozygosity (ROH) are related concepts that refer to the autozygosity in chromosome segments. However the formal relationship between their length distributions remains to be established. Here…
Usutu virus (USUV) is a flavivirus of the Japanese encephalitis complex transmitted between \textit{Culex} mosquitoes and birds, a transmission pattern similar to that of the West Nile virus (WNV). In Germany, the first case of USUV was…
Fitness landscapes provide a quantitative framework for understanding how natural selection shapes evolutionary trajectories. A central feature of these landscapes is their number of local optima, which determines whether fitness-increasing…
A fundamental problem in protobiological dynamics is to understand how chemically generated polymers can form persistent sequence distributions before the emergence of replication. We study deterministic polymer growth in which each finite…
Branch-specific substitution models are popular for detecting evolutionary change-points, such as shifts in selective pressure. However, applying such models typically requires prior knowledge of change-point locations on the phylogeny or…
Real ecosystems are characterized by sparse and asymmetric interactions, posing a major challenge to theoretical analysis. We introduce a new method to study the generalized Lotka-Volterra model with stochastic dynamics on sparse graphs. By…
Understanding and predicting evolutionary accumulation pathways is a key objective in many fields of research, ranging from classical evolutionary biology to diverse applications in medicine. In this context, we are often confronted with…
Forecasting disease spread is a critical tool to help public health officials design and plan public health interventions. However, the expected future state of an epidemic is not necessarily well defined as disease spread is inherently…
The tragedy of the commons has traditionally been framed as a problem of resource overuse driven by self-interested exploitation. In contrast, growing empirical evidence shows that insufficient use or abandonment of natural resources, known…
Epidemics have shaped human history, often with devastating consequences, motivating the development of mathematical models to understand and control their dynamics. Among the many aspects of epidemic behavior, the conditions that lead to…
Vector-borne diseases often infect multiple host species, increasing the likelihood of disease persistence due to the presence of multiple reservoirs. Vector biting patterns and feeding preferences can shift in response to selective…
Microbial populations exhibit a broad spectrum of nutrient utilization strategies, ranging from strategies utilizing diverse nutrients, called "generalists," to those being highly adapted to specific nutrients, called "specialists." The…
Biological evolution depends on the passing down to subsequent generations of genetic information encoding beneficial traits, and on the removal of unfit individuals by a selection mechanism. However, selection acts on phenotypes, and is…
Predicting species persistence within ecological communities is a fundamental challenge for both empirical and theoretical ecology. Existing methods span from mechanistic models, whose parameters are difficult to estimate from data, to…