其他定量生物学
Multiple cellular processes are triggered when the concentration of a regulatory protein reaches a critical threshold. Previous analyses have characterized timing statistics for single-gene systems. However, many biological timers are based…
The cryopreservation of biological materials is a highly complex process, as it involves numerous factors such as the cooling and thawing procedures, the administration of cryoprotective agents (CPAs), as well as the type and composition of…
The study was carried out to known the response of two industrial potato cultivars (Hermes, and Challenger) Netherlands origin, to chelated potassium fertilizer and humic acid due to growth, yield and quality in the fall season of 2024,…
The genus of Rumex from the Polygonaceae family is widespread in the world, particularly in the northern hemisphere, and includes about 250 species. The species of this genus are used for medicinal purposes and their allelopathic impacts.…
Animals that display behavioural flexibility and adaptability thrive in urban environments, due to their ability to exploit novel anthropogenic resources. Since humans are an important component of such urban environments, animals that…
This work presents a new framework for procedural generation of dynamic 3D plant model geometries, which has been implemented in the Helios modeling system. Key goals of this work were to develop a model that 1) has a generalized set of…
Bone marrow cell cytomorphology analysis is critical for the diagnosis of hematological malignancies but remains a labor-intensive process subject to significant inter-observer variability. While recent foundation models have shown promise…
Detecting walking pattern abnormalities in dairy cows early on holds the potential to reduce the occurrence of clinical lameness. This study aimed to predict gait scores in non-clinically lame dairy cows by using gait attributes based on…
Color fundus image (CFI) bounds detection and contrast enhancement are fundamental tasks in automatic CFI analysis. We present an open-source algorithm, published as a Python package, to automatically extract parametric bounds from color…
Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…
In recent years, multiplexed Fluorescence In Situ Hybridization (FISH) or FISH-omics methods have rapidly expanded, enabling the quantification of chromatin organization in single cells, often in conjunction with measurements of RNA and…
Hematology analyzers are essential diagnostic and monitoring tools for detecting blood diseases. Although contemporary analyzers produce only basic insights, they are often not as detailed as required under the personalized medicine…
Background: Hemiparesis after subcortical stroke is classically described as distal upper-extremity (UE) predominant, but prevalence data in chronic stroke is limited. Objective: Determine the prevalence of distal predominant UE weakness in…
Rapid advancements in technology have led to an increased use of artificial intelligence (AI) technologies in medicine and bioinformatics research. In anticipation of this, the National Institutes of Health (NIH) assembled the Bridge to…
Free-ranging dogs (Canis lupus familiaris) constitute the majority of the global dog population and rely heavily on human-derived resources. Studies show different levels of responses to various cues like food, petting and gazing by humans.…
Acute Myeloid Leukemia (AML) is a highly aggressive blood cancer with low survival rates. Hence, emphasizing the importance of the urgent need for effective treatment modalities. In recent times, the advances in cancer genomics have…
This study aimed to elucidate the oncogenic role of NSUN6 and its downstream molecular network in breast cancer cells,with a focus on proliferation and migration for the key drivers of tumor progression.
Biosecurity measures enforced by the swine industry are in place not only to protect a single farm, but also the vast community of interconnected swine farms. Vehicles play a role in disease movement and given that most pigs move throughout…
Medical imaging data plays a vital role in disease diagnosis, monitoring, and clinical research discovery. Biomedical data managers and clinical researchers must navigate a complex landscape of medical imaging infrastructure, input/output…
Animals employ strategic decision-making while carefully weighing nutritional benefits against the risks presented by aversive or harmful stimuli in their natural environment, to maximize foraging efficiency, In India, free-ranging dogs…