其他定量生物学

The present study evaluated In vitro effect of gentamicin sulfate and ceftiofur sodium on the viability of the Marek's disease virus. The titer of cell associated turkey herpesvirus (HVT) vaccine was not appreciably reduced when incubated…

The objective of this study was to determine the effect of feeding an antimicrobial association to males broiler chickens from 0 to 14 days of age on the performance and clinical signs of bacterial processes. Two treatments were tested: a…

An experiment was conducted to evaluate the effect of feeding post-weaned piglets different levels of a commercial amoxicillin plus norfloxacin formula (Respirend) on the performance, clinical evidence of sickness, and the cost:benefit…

I present here longitudinal evaluation of T and B cell immunity to SARS-CoV2 and variants of concern (VOC) from a single subject (me) over an entire year post vaccination. After enrolling in the Moderna phase III clinical trial, I collected…

Background: Calculation of the electric field induced by transcranial magnetic stimulation (TMS) in the brain requires accurate models of the stimulation coils. Reconstructing models from the measured magnetic fields of coils so far worked…

Animal-related outages (AROs) are a prevalent form of outages in electrical distribution systems. Animal-infrastructure interactions vary across focal species and regions, underlining the need to study the animal-outage relationship in more…

Space biology research aims to understand fundamental effects of spaceflight on organisms, develop foundational knowledge to support deep space exploration, and ultimately bioengineer spacecraft and habitats to stabilize the ecosystem of…

Human space exploration beyond low Earth orbit will involve missions of significant distance and duration. To effectively mitigate myriad space health hazards, paradigm shifts in data and space health systems are necessary to enable…

Statistical mechanics has grown without bounds in space. Statistical mechanics of point particles in an unbounded perfect gas is commonly accepted as a foundation for understanding many systems, including liquids like the concentrated salt…

Life has a special status, it even has its own science: biology. In many ways, the logic of life seems to differ from that of atoms, molecules, planets, or any other `inanimate object'. However, life is increasingly measured using…

Improvement of protein function by evolution (natural selection) is expected on general grounds, but even with the modern database positive proof has remained a difficult problem for theory. Here we extend our recent analysis of the…

If life on Earth had to achieve n 'hard steps' to reach humanity's level, then the chance of this event rose as time to the n-th power. Integrating this over habitable star formation and planet lifetime distributions predicts >99% of…

Despite 93.1% to 95.8% of the UK adult population having been vaccinated and currently 83.5% to 89.8% of adults having received at least two doses (1), and despite many households testing twice a week with lateral flow tests (2), R at the…

We investigate a method to extract relations from texts based on global alignment and syntactic information. Combined with SVM, this method is shown to have a performance comparable or even better than LSTM on two RE tasks.

The untenable dependence of cryopreservation on cytotoxic cryoprotectants has motivated the mining of biochemical libraries to identify molecular features marking cryoprotectants that may prevent ice crystal growth. It is hypothesized that…

A translation of the Dutch article from 1970 in which the term "bioinformatics" was first introduced by Ben Hesper and Paulien Hogeweg.

In this position paper, a large group of interdisciplinary experts outlines response strategies against the spread of SARS-CoV-2 in the winter of 2021/2022 in Germany. We review the current state of the COVID-19 pandemic, from incidence and…

This book handles the fatty liver disease from the bio-statistical point of view . It discusses the disease process in the simple general form of health-disease-death multi-states model . Continuous Time Markov Chains are used to estimate…

The primary aim of this work is to explore how proteins point mutations impact their marginal stability and, hence, their evolvability. With this purpose, we show that the use of four classic notions, namely, those from Leibniz & Kant…

Richard C. Lewontin is arguably the most influential evolutionary biologist of the second half of the 20th century. In this chapter, I provide two windows on his influential 1972 article "The Apportionment of Human Diversity": First, I show…