其他定量生物学
Since the completion of the human genome sequencing project in 2001, significant progress has been made in areas such as gene regulation editing and protein structure prediction. However, given the vast amount of genomic data, the segments…
The complexity of human biology and its intricate systems holds immense potential for advancing human health, disease treatment, and scientific discovery. However, traditional manual methods for studying biological interactions are often…
Objective: Ficus exasperata Vahl (Sandpaper tree) is extensively used in Nigeria to treat diseases, but a dearth of documentation about its toxicity exists. This information is crucial because pollutants can contaminate medicinal plants.…
Ligand-receptor interactions are fundamental to many biological processes. For example in antibody-based immunotherapies, the dynamics of an antibody binding with its target antigen directly influence the potency and efficacy of monoclonal…
Network control theory (NCT) has recently been utilized in neuroscience to facilitate our understanding of brain stimulation effects. A particularly useful branch of NCT is optimal control, which focuses on applying theoretical and…
How does the genome encode the form of the organism? What is the nature of this genomic code? Inspired by recent work in machine learning and neuroscience, we propose that the genome encodes a generative model of the organism. In this…
In France, government protection of unaccompanied minors (UMs) depends upon the recognition of their minority status and often result in a rejection. A significant proportion of UMs therefore find themselves unprotected. This qualitative…
Although previous observational studies have shown associations between serum 25-hydroxyvitamin D (25(OH)D) concentration and metabolic syndrome, this association has not yet been investigated among Aboriginal and Torres Strait Islander…
This study examines the phytochemical characteristics of Ayurvedic products. An analysis was performed on Kottakkal Ayurveda Triphala (T), Kottakkal Ayurveda Hinguvachadi Churnam (H), and Kottakkal Ayurveda Jirakadyarishtam (J) using GC-MS…
In this work, we applied the Chaos Game Representation (CGR) to the complete human genomic sequence T2T-CHM13v2.0, analyzing the entire chromosome assembly and each chromosome separately, including mitochondrial DNA. Multifractal spectra…
Rare diseases are collectively common, affecting approximately one in twenty individuals worldwide. In recent years, rapid progress has been made in rare disease diagnostics due to advances in DNA sequencing, development of new…
This study is a continuation of previous work, which highlights the nutrient enhancement by using rice straw (RS) and pressmud (PM) on vermicomposting. Herein, we demonstrate the significant impact of Moringa oleifera derived Cu/Ni/Co oxide…
This paper provides the mathematical expressions, formulated in classical trigonometric terms, that are required (i) to compute an animal's body orientations and rotations in 3D space from data acquired at high-frequency by on-board…
The translation of AI-generated brain metastases (BM) segmentation into clinical practice relies heavily on diverse, high-quality annotated medical imaging datasets. The BraTS-METS 2023 challenge has gained momentum for testing and…
Production of energy (metabolism) and its distribution is vital for living organisms, both at individual level - between different functions of an organism, as well as between species of communities at different organizational levels,…
One of the major characteristics of living organisms is metabolic rate, which is the amount of energy produced per unit of time. When the mass of organisms increases, the metabolic rate also increases (usually as a power function of mass),…
We present q2-fmt, a QIIME 2 plugin that provides diverse methods for assessing the extent of microbiome engraftment following fecal microbiota transplant. The methods implemented here were informed by a recent literature review on…
This paper statistically analysed pensioner longevity in Ghana. It fundamentally sought to ascertain the significant determinants of longevity amongst Ghanaian pensioners, specifically, SSNIT pensioners by estimating the mortality rate of…
Composition is a powerful principle for systems biology, focused on the interfaces, interconnections, and orchestration of distributed processes to enable integrative multiscale simulations. Whereas traditional models focus on the structure…
Chikungunya virus (CHIKV) is one of the most relevant arboviruses affecting public health today. It belongs to the Togaviridae family and alphavirus genus, causing an arthritogenic disease known as Chikungunya fever (CHIKF). This…