脑肿瘤分割挑战赛2023：预处理MRI上的脑转移瘤分割
其他定量生物学
2024-12-10 v3 图像与视频处理
摘要
将AI生成的脑转移瘤分割转化为临床实践，在很大程度上依赖于多样化、高质量且标注良好的医学影像数据集。BraTS-METS 2023挑战赛因使用经过严格标注的国际汇编真实世界数据集来测试和基准测试算法而获得了发展势头。本研究展示了该分割挑战赛的结果，并表征了影响获胜算法性能的挑战性案例。来自八个贡献的国际数据集的标准解剖MRI序列（T1、T2、FLAIR、T1PG）上未经治疗的脑转移瘤采用分步法进行标注：已发表的UNET算法、学生、神经放射科医生、最终批准的神经放射科医生。分割根据病灶级别的Dice和Hausdorff距离（HD95）分数进行排名。假阳性（FP）和假阴性（FN）受到严厉惩罚，Dice得分为0，HD95固定惩罚为374。包含1303项研究的八个数据集被标注，其中402项研究（3076个病灶）在Synapse上作为公开数据集发布以供参赛者挑战。此外，31项研究（139个病灶）被保留用于验证，59项研究（218个病灶）被用于测试。分割准确度以跨受试者的排名来衡量，获胜团队的病灶级别平均得分为7.9。领先团队的常见错误包括小病灶的假阴性以及掩膜在空间中的配准错误。BraTS-METS 2023挑战赛成功策划了标注良好、多样化的数据集并识别了常见错误，促进了跨不同临床环境的BM分割转化，并为接受BM治疗的患者提供个性化的体积报告。
引用
@article{arxiv.2306.00838,
title = {The Brain Tumor Segmentation (BraTS-METS) Challenge 2023: Brain Metastasis Segmentation on Pre-treatment MRI},
author = {Ahmed W. Moawad and Anastasia Janas and Ujjwal Baid and Divya Ramakrishnan and Rachit Saluja and Nader Ashraf and Nazanin Maleki and Leon Jekel and Nikolay Yordanov and Pascal Fehringer and Athanasios Gkampenis and Raisa Amiruddin and Amirreza Manteghinejad and Maruf Adewole and Jake Albrecht and Udunna Anazodo and Sanjay Aneja and Syed Muhammad Anwar and Timothy Bergquist and Veronica Chiang and Verena Chung and Gian Marco Conte and Farouk Dako and James Eddy and Ivan Ezhov and Nastaran Khalili and Keyvan Farahani and Juan Eugenio Iglesias and Zhifan Jiang and Elaine Johanson and Anahita Fathi Kazerooni and Florian Kofler and Kiril Krantchev and Dominic LaBella and Koen Van Leemput and Hongwei Bran Li and Marius George Linguraru and Xinyang Liu and Zeke Meier and Bjoern H Menze and Harrison Moy and Klara Osenberg and Marie Piraud and Zachary Reitman and Russell Takeshi Shinohara and Chunhao Wang and Benedikt Wiestler and Walter Wiggins and Umber Shafique and Klara Willms and Arman Avesta and Khaled Bousabarah and Satrajit Chakrabarty and Nicolo Gennaro and Wolfgang Holler and Manpreet Kaur and Pamela LaMontagne and MingDe Lin and Jan Lost and Daniel S. Marcus and Ryan Maresca and Sarah Merkaj and Gabriel Cassinelli Pedersen and Marc von Reppert and Aristeidis Sotiras and Oleg Teytelboym and Niklas Tillmans and Malte Westerhoff and Ayda Youssef and Devon Godfrey and Scott Floyd and Andreas Rauschecker and Javier Villanueva-Meyer and Irada Pfluger and Jaeyoung Cho and Martin Bendszus and Gianluca Brugnara and Justin Cramer and Gloria J. Guzman Perez-Carillo and Derek R. Johnson and Anthony Kam and Benjamin Yin Ming Kwan and Lillian Lai and Neil U. Lall and Fatima Memon and Mark Krycia and Satya Narayana Patro and Bojan Petrovic and Tiffany Y. So and Gerard Thompson and Lei Wu and E. Brooke Schrickel and Anu Bansal and Frederik Barkhof and Cristina Besada and Sammy Chu and Jason Druzgal and Alexandru Dusoi and Luciano Farage and Fabricio Feltrin and Amy Fong and Steve H. Fung and R. Ian Gray and Ichiro Ikuta and Michael Iv and Alida A. Postma and Amit Mahajan and David Joyner and Chase Krumpelman and Laurent Letourneau-Guillon and Christie M. Lincoln and Mate E. Maros and Elka Miller and Fanny Moron and Esther A. Nimchinsky and Ozkan Ozsarlak and Uresh Patel and Saurabh Rohatgi and Atin Saha and Anousheh Sayah and Eric D. Schwartz and Robert Shih and Mark S. Shiroishi and Juan E. Small and Manoj Tanwar and Jewels Valerie and Brent D. Weinberg and Matthew L. White and Robert Young and Vahe M. Zohrabian and Aynur Azizova and Melanie Maria Theresa Bruseler and Mohanad Ghonim and Mohamed Ghonim and Abdullah Okar and Luca Pasquini and Yasaman Sharifi and Gagandeep Singh and Nico Sollmann and Theodora Soumala and Mahsa Taherzadeh and Philipp Vollmuth and Martha Foltyn-Dumitru and Ajay Malhotra and Aly H. Abayazeed and Francesco Dellepiane and Philipp Lohmann and Victor M. Perez-Garcia and Hesham Elhalawani and Maria Correia de Verdier and Sanaria Al-Rubaiey and Rui Duarte Armindo and Kholod Ashraf and Moamen M. Asla and Mohamed Badawy and Jeroen Bisschop and Nima Broomand Lomer and Jan Bukatz and Jim Chen and Petra Cimflova and Felix Corr and Alexis Crawley and Lisa Deptula and Tasneem Elakhdar and Islam H. Shawali and Shahriar Faghani and Alexandra Frick and Vaibhav Gulati and Muhammad Ammar Haider and Fatima Hierro and Rasmus Holmboe Dahl and Sarah Maria Jacobs and Kuang-chun Jim Hsieh and Sedat G. Kandemirli and Katharina Kersting and Laura Kida and Sofia Kollia and Ioannis Koukoulithras and Xiao Li and Ahmed Abouelatta and Aya Mansour and Ruxandra-Catrinel Maria-Zamfirescu and Marcela Marsiglia and Yohana Sarahi Mateo-Camacho and Mark McArthur and Olivia McDonnell and Maire McHugh and Mana Moassefi and Samah Mostafa Morsi and Alexander Munteanu and Khanak K. Nandolia and Syed Raza Naqvi and Yalda Nikanpour and Mostafa Alnoury and Abdullah Mohamed Aly Nouh and Francesca Pappafava and Markand D. Patel and Samantha Petrucci and Eric Rawie and Scott Raymond and Borna Roohani and Sadeq Sabouhi and Laura M. Sanchez-Garcia and Zoe Shaked and Pokhraj P. Suthar and Talissa Altes and Edvin Isufi and Yaseen Dhemesh and Jaime Gass and Jonathan Thacker and Abdul Rahman Tarabishy and Benjamin Turner and Sebastiano Vacca and George K. Vilanilam and Daniel Warren and David Weiss and Fikadu Worede and Sara Yousry and Wondwossen Lerebo and Alejandro Aristizabal and Alexandros Karargyris and Hasan Kassem and Sarthak Pati and Micah Sheller and Katherine E. Link and Evan Calabrese and Nourel hoda Tahon and Ayman Nada and Yuri S. Velichko and Spyridon Bakas and Jeffrey D. Rudie and Mariam Aboian},
journal= {arXiv preprint arXiv:2306.00838},
year = {2024}
}