医学物理
Gamma camera imaging is an important technique in nuclear medicine. It is capable of diagnostic imaging of metabolically active areas and organ function, and it can be used to evaluate blood flow in the heart muscle, measure bone growth,…
Chest physiotherapy is a set of techniques used to help the draining of the mucus from the lung in pathological situations. The choice of the techniques, and their adjustment to the patients or to the pathologies, remains as of today…
Thoracic endovascular aortic repair (TEVAR) has become the standard treatment of a variety of aortic pathologies. The objective of this study is to evaluate the hemodynamic effects of stent-graft introducer sheath during TEVAR. Three…
Magnetic Resonance Fingerprinting (MRF) is a method to extract quantitative tissue properties such as T1 and T2 relaxation rates from arbitrary pulse sequences using conventional magnetic resonance imaging hardware. MRF pulse sequences have…
Heart failure is a leading cause of mortality in the Western world. The mouse is a widely used model for a number of diseases, induced by genetic modification or surgical intervention. When performing experiments in mice, in vivo magnetic…
Magneto-acousto-electrical tomography (MAET), a combination of ultrasound imaging and electrical impedance tomography (EIT), offers both high resolution (in comparison to EIT) and high contrast (in comparison to ultrasound imaging). It is…
Reversed Potts shunt (PS) was suggested as palliation for patients with suprasystemic pulmonary arterial hypertension (PAH) and right ventricular (RV) failure. PS, however, can result in poorly understood mortality. Here, a patient-specific…
We develop a new three-dimensional time-dependent radiative transfer code, TRINITY (Time-dependent Radiative transfer In Near-Infrared TomographY), for in-vivo diffuse optical tomography (DOT). The simulation code is based on the design of…
Purpose: Universal Pulses (UPs) are excitation pulses that reduce the flip angle inhomogeneity in high field MRI systems without subject-specific optimization, originally developed for parallel transmit (PTX) systems at 7T. We investigated…
This study investigates the influence of several Monte Carlo radiation transport codes and nuclear models on the simulation of secondary neutron spectra and its impact on calculating and measuring neutron doses in proton therapy. Three…
Purpose: To implement and evaluate a new dictionary-based technique for native myocardial T1 and T2 mapping using Cartesian sampling. Methods: The proposed technique (Multimapping) consisted of single-shot Cartesian image acquisitions in 10…
Computational hemodynamics is becoming an increasingly important tool in clinical applications and surgical procedures involving the cardiovascular system. Aim of this review is to provide a compact summary of state of the art 0D-1D…
TCoMX (Tomotherapy Complexity Metrics EXtractor) is a newly developed tool for the automatic extraction of complexity metrics from the DICOM RT-PLAN files of helical tomotherapy (HT) treatments. TCoMX allows the extraction of all the…
Time-of-flight neutron imaging offers complementary attenuation contrast to X-ray computed tomography (CT), coupled with the ability to extract additional information from the variation in attenuation as a function of neutron energy (time…
Soft tissues - such as ligaments and tendons - primarily consist of solid (collagen, predominantly) and liquid phases. Understanding the interaction between such components and how they change under physiological loading sets the basis for…
Visible light optical coherence tomography (vis-OCT) provides a unique tool for imaging the structure and oxygen metabolism in tissues. However, since it works in the spectral domain, vis-OCT still suffers from noises due to the multiple…
Dual Energy Cone Beam Computed Tomography (DE-CBCT) is a promising technique for several medical applications, including dynamic angiography. Recently, a dynamical two-step method has been proposed : first, the water and iodine projections…
Objective: To investigate cardiac activation maps estimated using electrocardiographic imaging and to find methods reducing line-of-block (LoB) artifacts, while preserving real LoBs. Methods: Body surface potentials were computed for 137…
Heavy-ion therapy, particularly using scanned (active) beam delivery, provides a precise and highly conformal dose distribution, with maximum dose deposition for each pencil beam at its endpoint (Bragg peak), and low entrance and exit dose.…
Computational models have become an essential part of exploratory protocols in cell biology, as a complement to in vivo or in vitro experiments. These virtual models have the twofold advantage of enabling access to new types of data and…