计算工程、金融与科学
Coronary Microvascular Dysfunction (CMD) is characterized by impaired vasodilation and can lead to insufficient blood flow to the myocardium during stress or exertion, affecting millions of people globally. Despite their diagnostic value,…
The liberalisation of the European passenger railway markets through the European Directive EU 91/440/EEC states a new scenario where different Railway Undertakings compete with each other in a bidding process for time slots. The…
We introduce an adjoint-based aerodynamic shape optimization framework that integrates a diffusion model trained on existing designs to learn a smooth manifold of aerodynamically viable shapes. This manifold is enforced as an equality…
Deep neural networks (DNNs) have garnered significant attention in financial asset pricing, due to their strong capacity for modeling complex nonlinear relationships within financial data. However, sophisticated models are prone to…
Digital engineering has transformed the design and development process. However, the utility of digital engineering is fundamentally dependent on the assumption that a simulation provides information consistent with reality. This…
Dental crowns are essential dental treatments for restoring damaged or missing teeth of patients. Recent design approaches of dental crowns are carried out using commercial dental design software. Once a scan of a preparation is uploaded to…
This paper proposes a reinforcement learning framework for performance-driven structural design that combines bottom-up design generation with learned strategies to efficiently search large combinatorial design spaces. Motivated by the…
Physics-informed holomorphic neural networks (PIHNNs) have recently emerged as efficient surrogate models for solving differential problems. By embedding the underlying problem structure into the network, PIHNNs require training only to…
For centuries, financial institutions have responded to liquidity challenges by forming closed, centralized clearing clubs with strict rules and membership that allow them to collaborate on using the least money to discharge the most debt.…
This paper introduces a high order numerical framework for efficient and robust simulation of compressible flows. To address the inefficiencies of standard hybridized discontinuous Galerkin (HDG) methods in large scale settings, we develop…
Loosely coupled partitioned methods for multiphysics problems treat each subproblem as a separate entity and advance them independently in time. In so doing these methods enable code reuse, increase concurrency and provide a convenient…
Training neural networks can be challenging, especially as the complexity of the problem increases. Despite using wider or deeper networks, training them can be a tedious process, especially if a wrong choice of the hyperparameter is made.…
During brittle crack propagation, a smooth crack front curve frequently becomes disjoint, generating a stepped crack and a material ligament that unites the newly formed crack fronts. These universal features fundamentally alter the…
Our fully kinetic, implicit Particle-in-Cell (PIC) simulations of global magnetospheres on up to 32,768 of El Capitan's AMD Instinct MI300A Accelerated Processing Units (APUs) represent an unprecedented computational capability that…
Stock price movements are influenced by many factors, and alongside historical price data, tex-tual information is a key source. Public news and social media offer valuable insights into market sentiment and emerging events. These sources…
Developing clinically viable tissue-engineered cardiovascular implants remains a formidable challenge. Achieving reliable and durable outcomes requires a deeper understanding of the fundamental mechanisms driving tissue evolution during in…
Topology optimization (TO) in two dimensions often presents a trade-off between structural performance and manufacturability, with unpenalized (variable-thickness) methods yielding superior but complex designs, and penalized (SIMP) methods…
As demand for high-purity lithium surges with the growth of the electric vehicle (EV) industry, cost-effective extraction from lower-grade North American sources like the Smackover Formation is critical. These resources, unlike high-purity…
Designing mutations to optimize protein thermostability remains challenging due to the complex relationship between sequence variations, structural dynamics, and thermostability, often assessed by \delta\delta G (the change in free energy…
Phase-field equations, mostly solved numerically, are known for capturing the mesoscale microstructural evolution of a material. However, such numerical solvers are computationally expensive as it needs to generate fine mesh systems to…