利用 X 射线激光对纳米颗粒系综进行三维衍射成像
应用物理
2020-07-28 v1 图像与视频处理
光学
摘要
我们报道了利用 X 射线单颗粒成像（SPI）测定金纳米颗粒（AuNPs）三维结构的结果。在欧洲 X 射线自由电子激光装置的新能力支持下（可每秒测量 1500 帧），在不足 100 小时的束流时间内测量了约 1000 万张金纳米颗粒衍射图样，数据量超过此前任何单次 SPI 实验的 100 倍。我们开发了分类与结构排序方法以厘清颗粒的非均匀性，并获得优于 3 nm 的分辨率。借助这些新的实验与分析进展，SPI 方法已进入新时代，且迈向近原子分辨率生物分子成像的路径已清晰可见。
引用
@article{arxiv.2007.13597,
title = {3D diffractive imaging of nanoparticle ensembles using an X-ray laser},
author = {Kartik Ayyer and P. Lourdu Xavier and Johan Bielecki and Zhou Shen and Benedikt J. Daurer and Amit K. Samanta and Salah Awel and Richard Bean and Anton Barty and Tomas Ekeberg and Armando D. Estillore and Klaus Giewekemeyer and Mark S. Hunter and Richard A. Kirian and Henry Kirkwood and Yoonhee Kim and Jayanath Koliyadu and Holger Lange and Romain Letruin and Jannik Lübke and Andrew J. Morgan and Nils Roth and Tokushi Sato and Marcin Sikorski and Florian Schulz and John C. H. Spence and Patrik Vagovic and Tamme Wollweber and Lena Worbs and Oleksandr Yefanov and Yulong Zhuang and Filipe R. N. C. Maia and Daniel A. Horke and Jochen Küpper and N. Duane Loh and Adrian P. Mancuso and Henry N. Chapman},
journal= {arXiv preprint arXiv:2007.13597},
year = {2020}
}
备注
25 pages, 5 main figures, 6 supplementary figures, 2 supplementary movies (link in document)