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The reconstruction of phylogenies from DNA or protein sequences is a major task of computational evolutionary biology. Common phenomena, notably variations in mutation rates across genomes and incongruences between gene lineage histories,…

Probability · Mathematics 2012-11-30 Elchanan Mossel , Sebastien Roch

We consider a discrete-time Markov chain, called fragmentation process, that describes a specific way of successively removing objects from a linear arrangement. The process arises in population genetics and describes the ancestry of the…

Probability · Mathematics 2020-03-17 Ellen Baake , Mareike Esser

Phylogenetic analyses of gene expression have great potential for addressing a wide range of questions. These analyses will, for example, identify genes that have evolutionary shifts in expression that are correlated with evolutionary…

Populations and Evolution · Quantitative Biology 2014-01-14 Casey W. Dunn , Xi Luo , Zhijin Wu

We consider a branching model in discrete time where each individual has a trait in some general state space. Both the reproduction law and the trait inherited by the offsprings may depend on the trait of the mother and the environment. We…

Probability · Mathematics 2013-11-26 Vincent Bansaye

Cancer prognosis can be regarded as estimating the risk of future outcomes from multiple variables. In prognostic signatures, these variables represent expressions of genes that are summed up to calculate a risk score. However, it is a…

The psychology of the individual is continuously changing in nature, which has a significant influence on the evolutionary dynamics of populations. To study the influence of the continuously changing psychology of individuals on the…

Social and Information Networks · Computer Science 2025-02-11 Minyu Feng , Bin Pi , Liang-Jian Deng , Jürgen Kurths

How many parameters are required for a model to execute a given task? It has been argued that large language models, pre-trained via self-supervised learning, exhibit emergent capabilities such as multi-step reasoning as their number of…

Machine Learning · Computer Science 2024-09-23 Ingvar Ziemann , Nikolai Matni , George J. Pappas

We consider a broadcasting problem on a tree where a binary digit (e.g., a spin or a nucleotide's purine/pyrimidine type) is propagated from the root to the leaves through symmetric noisy channels on the edges that randomly flip the state…

Probability · Mathematics 2025-01-24 David Clancy , Hanbaek Lyu , Sebastien Roch , Allan Sly

In mathematical phylogenetics, evolutionary relationships are often represented by trees and networks. The latter are typically used whenever the relationships cannot be adequately described by a tree, which happens when so-called…

Populations and Evolution · Quantitative Biology 2025-12-05 Mirko Wilde , Mareike Fischer

We consider an interacting particle Markov process for Darwinian evolution in an asexual population with non-constant population size, involving a linear birth rate, a density-dependent logistic death rate, and a probability $\mu$ of…

Probability · Mathematics 2007-05-23 Nicolas Champagnat

By introducing the notions of living and dead nodes a new model of random tree evolution with continuous time parameter has been constructed. It is assumed that two random variables, the lifetime and the offspring number of living nodes…

Statistical Mechanics · Physics 2007-05-23 L. Pal

Optimal designs minimize the number of experimental runs (samples) needed to accurately estimate model parameters, resulting in algorithms that, for instance, efficiently minimize parameter estimate variance. Governed by knowledge of past…

Methodology · Statistics 2023-02-03 Nicholas W. Barendregt , Emily G. Webb , Zachary P. Kilpatrick

Markov chains with variable length are useful parsimonious stochastic models able to generate most stationary sequence of discrete symbols. The idea is to identify the suffixes of the past, called contexts, that are relevant to predict the…

Machine Learning · Computer Science 2022-01-10 Victor Freguglia , Nancy Garcia

We consider a general honest homogeneous continuous-time Markov process with restarts. The process is forced to restart from a given distribution at time moments generated by an independent Poisson process. The motivation to study such…

Probability · Mathematics 2012-06-26 Konstantin Avrachenkov , Alexei Piunovskiy , Zhang Yi

Species tree reconstruction from genomic data is increasingly performed using methods that account for sources of gene tree discordance such as incomplete lineage sorting. One popular method for reconstructing species trees from unrooted…

Populations and Evolution · Quantitative Biology 2017-12-06 Shubhanshu Shekhar , Sebastien Roch , Siavash Mirarab

A popular line of research in evolutionary biology is the use of time-calibrated phylogenies for the inference of diversification processes. This requires computing the likelihood of a given ultrametric tree as the reconstructed tree…

Populations and Evolution · Quantitative Biology 2013-01-24 Amaury Lambert , Hélène Morlon , Rampal S. Etienne

We survey results on the description of stochastically evolving genealogies of populations and marked genealogies of multitype populations or spatial populations via tree-valued Markov processes on (marked) ultrametric measure spaces. In…

Probability · Mathematics 2018-09-21 Andrej Depperschmidt , Andreas Greven

Many biological studies involve inferring the evolutionary history of a sample of individuals from a large population and interpreting the reconstructed tree. Such an ascertained tree typically represents only a small part of a…

Populations and Evolution · Quantitative Biology 2024-08-13 Michael Celentano , William S. DeWitt , Sebastian Prillo , Yun S. Song

The widespread use of large language models (LLMs) raises an important question: how do texts evolve when they are repeatedly processed by LLMs? In this paper, we define this iterative inference process as Markovian generation chains, where…

Computation and Language · Computer Science 2026-03-13 Mingmeng Geng , Amr Mohamed , Guokan Shang , Michalis Vazirgiannis , Thierry Poibeau

Consider an information source generating a symbol at the root of a tree network whose links correspond to noisy communication channels, and broadcasting it through the network. We study the problem of reconstructing the transmitted symbol…

Statistical Mechanics · Physics 2009-11-11 Marc Mezard , Andrea Montanari
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