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Aging is a fundamental aspect of living systems that undergo a progressive deterioration of physiological function with age and an increase of vulnerability to disease and death. Living systems, known as complex systems, require complexity…

Populations and Evolution · Quantitative Biology 2010-11-15 Byung Mook Weon , Jung Ho Je

We examine what happens in a population when it experiences an abrupt change in surrounding conditions. Several cases of such "abrupt transitions" for both physical and living social systems are analyzed from which it can be seen that all…

Physics and Society · Physics 2016-03-23 Peter Richmond , Bertrand M. Roehner

This work introduces a Bayesian smoothing approach for the joint graduation of mortality rates across multiple populations. In particular, dynamical linear models are used to induce smoothness across ages through structured dependence,…

The aim of this study is to compare the growth speed of different cell populations measured by their Malthus parameter. We focus on both the age-structured and size-structured equations. A first population (of reference) is composed of…

Probability · Mathematics 2017-03-02 Adélaïde Olivier

Biologists have found that the death rate of cells in culture depends upon their spatial density. Permanent "Stay alive" signals from their neighbours seem to prevent them from dying. In a previous paper (Wang et al. 2013) we gave evidence…

Physics and Society · Physics 2013-06-24 Lei Wang , Yijuan Xu , Zengru Di , Bertrand M. Roehner

Understanding and modeling mortality patterns, especially differences in mortality rates between populations, is vital for demographic analysis and public health planning. We compare three statistical models within the age-period framework…

Applications · Statistics 2025-10-14 Giacomo Lanfiuti Baldi , Andrea Nigri , Han Lin Shang

We consider the effect of non-constant parameters on the human-forest interaction logistic model coupled with human technological growth introduced in "Deforestation and world population sustainability: a quantitative analysis"[1]. In…

Populations and Evolution · Quantitative Biology 2021-12-21 Gerardo Aquino , Mauro Bologna

Biological aging is characterized by an age-dependent increase in the probability of death and by a decrease in the reproductive capacity. Individual age-dependent rates of survival and reproduction have a strong impact on population…

Populations and Evolution · Quantitative Biology 2016-02-03 Arian Šajina , Dario Riccardo Valenzano

We twice modify the Penna model for biological ageing. First we introduce back (good) mutations and a memory for them into the model. It allows us to observe an improvement of the species fitness over long time scales as well as punctuated…

Statistical Mechanics · Physics 2015-06-24 S. Moss de Oliveira , D. Stauffer , P. M. C de Oliveira , J. S. Sa Martins

New models for evolutionary processes of mutation accumulation allow hypotheses about the age-specificity of mutational effects to be translated into predictions of heterogeneous population hazard functions. We apply these models to…

Populations and Evolution · Quantitative Biology 2009-08-27 Kenneth W. Wachter , David R. Steinsaltz , Steven N. Evans

There have been significant efforts devoted to solving the longevity risk given that a continuous growth in population ageing has become a severe issue for many developed countries over the past few decades. The Cairns-Blake-Dowd (CBD)…

Applications · Statistics 2024-12-30 Ka Kin Lam , Bo Wang

Although traditional literature on mortality modeling has focused on single countries in isolation, recent contributions have progressively moved toward joint models for multiple countries. Besides favoring borrowing of information to…

Applications · Statistics 2025-04-08 Giovanni Romanò , Emanuele Aliverti , Daniele Durante

In this article, we deal with COVID-19 data to study the trend of the epidemic at the global situation. Choosing the mortality rate as an appropriate metric which measures the relative relation between the cumulative confirmed cases and…

Applications · Statistics 2020-11-06 Zixuan Han , Tao Li , Jinghong You

The chronological age used in demography describes the linear evolution of the life of a living being. The chronological age cannot give precise information about the exact developmental stage or aging processes an organism has reached. On…

Analysis of PDEs · Mathematics 2023-10-02 Jacques Demongeot , Pierre Magal

Improving health worldwide will require rigorous quantification of population-level trends in health status. However, global-level surveys are not available, forcing researchers to rely on fragmentary country-specific data of varying…

Methodology · Statistics 2014-05-20 Mariel M. Finucane , Christopher J. Paciorek , Goodarz Danaei , Majid Ezzati

Using fine-grained, publicly available data, this paper studies the short-term association between environmental factors, i.e., weather and air pollution characteristics, and weekly mortality rates in small geographical regions in Europe.…

Applications · Statistics 2024-10-07 Jens Robben , Katrien Antonio , Torsten Kleinow

Existing mortality forecasting methods focus on age-specific mortality rates, which lie in an unconstrained space and overlook the distributional nature of life-table death counts. Few studies have developed and compared forecasting methods…

Methodology · Statistics 2026-04-23 Han Lin Shang , Cristian F. Jiménez-Varón

Mortality is an instrument of natural selection. Evolutionary motivated theories imply its irreversibility and life history dependence. This is inconsistent with mortality data for protected populations. Accurate analysis yields mortality…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Mark Ya. Azbel'

The Makeham term is a crucial element in mortality modeling, representing a constant additive hazard that addresses background mortality factors unrelated to aging. Widely used in mortality analysis, this term enables the capture of risks…

Applications · Statistics 2024-09-09 Silvio C. Patricio , Trifon I. Missov

Suppose, contrary to fact, in 1950, we had put the cohort of 18 year old non-smoking American men on a stringent mandatory diet that guaranteed that no one would ever weigh more than their baseline weight established at age 18. How would…

Applications · Statistics 2008-02-06 James Robins