Vital rates from the action of mutation accumulation
Populations and Evolution
2009-08-27 v2
Abstract
New models for evolutionary processes of mutation accumulation allow hypotheses about the age-specificity of mutational effects to be translated into predictions of heterogeneous population hazard functions. We apply these models to questions in the biodemography of longevity, including proposed explanations of Gompertz hazards and mortality plateaus, and use them to explore the possibility of melding evolutionary and functional models of aging.
Keywords
Cite
@article{arxiv.0808.3622,
title = {Vital rates from the action of mutation accumulation},
author = {Kenneth W. Wachter and David R. Steinsaltz and Steven N. Evans},
journal= {arXiv preprint arXiv:0808.3622},
year = {2009}
}
Comments
17 pages, 7 figures