Related papers: Distributions of positron-emitting nuclei in proto…
The transport of neutrons in long beamlines at spallation neutron sources presents a unique challenge for Monte-Carlo transport calculations. This is due to the need to accurately model the deep-penetration of high-energy neutrons through…
Purpose: The presence of respiratory motion during radiation treatment leads to degradation of the expected dose distribution, both for target coverage and healthy-tissue sparing, particularly for techniques like pencil-beam scanning proton…
We provide ingredients and recipes for computing signals of TeV-scale Dark Matter annihilations and decays in the Galaxy and beyond. For each DM channel, we present the energy spectra of electrons and positrons, antiprotons, antideuterons,…
Intensity modulated proton therapy (IMPT) is an advanced cancer treatment modality that offers significant advantages over conventional X-ray therapies, particularly in its ability to minimize radiation dose beyond the tumor target. This…
In living organisms the positron-electron annihilation (occurring during the PET imaging) proceeds in about 30% via creation of a metastable ortho-positronium atom. In the tissue, due to the pick-off and conversion processes, over 98% of…
This study explores the production of radionuclides in a PMMA (Polymethylmethacrylate) phantom irradiated with Very High Energy Electrons (VHEE) beams as a novel method for dose verification. In this work, Monte Carlo simulation studies…
Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments is still a matter of research. A possible technique exploits the information…
Positron Emission Tomography using 2-[18F]-2deoxy-D-glucose as radiotracer (FDG-PET) is currently one of the most frequently applied functional imaging methods in clinical applications. The interpretation of FDG-PET data requires…
Positron annihilation in solid state matter can be utilized to detect and identify open-volume defects. The momentum distribution of the annihilation radiation is an important observable in positron-based measurements, and can reveal…
Proton momentum distributions of the $^{12}C$, $^{16}O$, $^{40}Ca$, $^{56}Fe$ and $^{208}$Pb nuclei are calculated by a model using the natural orbital representation and the experimental data for the momentum distribution of the $^{4}He$…
In the context of particle therapy monitoring, we are developing a gamma-ray detector to determine the ion range in vivo from the measurement of particle time-of-flight. For this application, a beam monitor capable to tag in time the…
Purpose: Analysis of [18F]-Fluorodeoxyglucose (FDG) kinetics in cancer has been most often limited to the evaluation of the average uptake over relatively large volumes. Nevertheless, tumor lesion almost contains inflammatory infiltrates…
In this paper we investigate, with a detailed Monte-Carlo simulation based on Geant4, the novel approach [Nucl. Instrum. Methods A588 (2008) 457] to 3D imaging with photon scattering. A monochromatic and well collimated gamma beam is used…
Measuring the Doppler broadening of the positron annihilation radiation or the angular correlation between the two annihilation gamma quanta reflects the momentum distribution of electrons seen by positrons in the material.Vacancy-type…
Purpose: To develop a Monte Carlo (MC) therapeutic dose calculation toolkit of a recently released ring gantry linac in Geant4 (Version 10.7) for secondary dose validation of radiotherapy plan. Methods: For the Halcyon (Varian Medical…
The bremsstrahlung spectra produced by electrons impinging on thick targets are simulated using the Geant4 Monte Carlo toolkit. Simulations are validated against experimental data available in literature for a range of energy between 0.5…
Charged particle beams are used in Particle Therapy (PT) to treat oncological patients due to their selective dose deposition in tissues and to their high biological effect in killing cancer cells with respect to photons and electrons used…
Cosmic-ray muons are highly penetrative charged particles that are observed at sea level with a flux of approximately one per square centimetre per minute. They interact with matter primarily through Coulomb scattering, which is exploited…
We propose a generic empirical formula for total inelastic cross-sections for various target nuclei scattered by a proton at different energies, which is applicable over a wide range of energy from $15 ~MeV$ to $1~ TeV$. The proposed model…
In vivo assessment of cancer and precise location of altered tissues at initial stages of molecular disorders are important diagnostic challenges. Positronium is copiously formed in the free molecular spaces in the patient's body during…