English

Radionuclide Production for Dose Verification in VHEE FLASH Radiotherapy

Medical Physics 2025-05-28 v1

Abstract

This study explores the production of radionuclides in a PMMA (Polymethylmethacrylate) phantom irradiated with Very High Energy Electrons (VHEE) beams as a novel method for dose verification. In this work, Monte Carlo simulation studies using the Geant4 toolkit and experimental measurements with a VHEE beam produced by a laser-plasma accelerator were conducted. Specifically, the photonuclear production of 11C, 15O and 13N is examined, with a detailed analysis of their spatial distribution, production yields and decay time

Keywords

Cite

@article{arxiv.2505.21183,
  title  = {Radionuclide Production for Dose Verification in VHEE FLASH Radiotherapy},
  author = {Francesco Urso and Federica Baffigi and Esther Ciarrocchi and Leonida Antonio Gizzi and Petra Koester and Luca Labate and Matteo Morrocchi and Simona Piccinini and Martina Salvadori and Maria Giuseppina Bisogni},
  journal= {arXiv preprint arXiv:2505.21183},
  year   = {2025}
}

Comments

Submitted to Nuclear Instruments and Methods in Physics Research Section A Proceedings(VCI2025)