Related papers: Radionuclide Production for Dose Verification in V…
Very high energy electrons (VHEE) in the 50-250 MeV range, delivered in short pulses at ultra-high dose rates, are proposed for clinical FLASH radiotherapy (RT) targeting deep-seated tumors. The clinical implementation of VHEE-FLASH RT…
Radiotherapy using very high-energy electron (VHEE) beams generated by a laser-plasma accelerator has garnered significant interest due to its dose distribution capabilities and potential to address limitations of traditional photon-based…
Radiotherapy with Very High Energy Electron (VHEE) beams is being extensively investigated for the treatment of deep-seated tumours, even in view of novel protocols based on the so-called FLASH effect. Laser WakeField Acceleration (LWFA)…
Radiochromic films (RCFs) offer valuable two-dimensional dosimetry capabilities with a conceptually simple operating principle that requires minimal investment, making them particularly suitable for very high energy electron (VHEE) FLASH…
Measurements performed with the purpose of characterizing the charged secondary radiation for dose release monitoring in particle therapy are reported. Charged secondary yields, energy spectra and emission profiles produced in poly-methyl…
Nowadays there is a growing interest in Particle Therapy treatments exploiting light ion beams against tumors due to their enhanced Relative Biological Effectiveness and high space selectivity. In particular promising results are obtained…
Recent blazar detections by HESS, MAGIC, and VERITAS suggest that very-high-energy (VHE, E > 100 GeV) gamma-rays may be produced in most, if not all, types of blazars, including those that possess intense circumnuclear radiation fields. In…
Monte Carlo simulations have been performed in order to evaluate the efficiencies of several light ions identification techniques. The detection system was composed with layers of scintillating material to measure either the deposited…
The use of very high energy electron (VHEE) beams for radiotherapy has been actively studied for over two decades due to their advantageous dose distribution, deep penetration depth and great potential of ultra-high dose-rate irradiation.…
Hadrontherapy is an emerging technique in cancer therapy that uses beams of charged particles. To meet the improved capability of hadrontherapy in matching the dose release with the cancer position, new dose monitoring techniques need to be…
Ultra-intense MeV photon and neutron beams are indispensable tools in many research fields such as nuclear, atomic and material science as well as in medical and biophysical applications. For astrophysical applications aimed for laboratory…
Charged particle beams are used in Particle Therapy (PT) to treat oncological patients due to their selective dose deposition in tissues and to their high biological effect in killing cancer cells with respect to photons and electrons used…
Very high-energy gamma-rays (VHE; E>100 GeV) have been detected from the direction of the Galactic Centre up to energies E>10 TeV. Up to now, the origin of this emission is unknown due to the limited positional accuracy of the observing…
The FLASH effect holds significant potential in improving radiotherapy treatment outcomes. Very high energy electrons (VHEEs) can effectively target tumors deep in the body and can be accelerated to achieve ultra-high dose rates (UHDR),…
Depth distributions of positron-emitting nuclei in PMMA phantoms are calculated within a Monte Carlo model for Heavy-Ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.0). The calculated total production rates of $^{11}$C, $^{10}$C…
The Booster Neutrino Experiment (MiniBooNE) searches for numu-to-nue oscillations using the O(1 GeV) neutrino beam produced by the Booster synchrotron at the Fermi National Accelerator Laboratory (FNAL). The Booster delivers protons with 8…
The flat spectrum radio quasar (FSRQ) 4C +21.35 (PKS 1222+216) displays prominent nuclear infrared emission from ~1200 K dust. A 70 -- 400 GeV flare with ~10 min variations during half an hour of observations was found by the MAGIC…
A proton pencil beam is associated with a surrounding low-dose envelope, originating from nuclear interactions. It is important for treatment planning systems to accurately model this envelope when performing dose calculations for pencil…
We discuss the possibility of creating novel research tools by producing and storing highly relativistic beams of highly ionised atoms in the CERN accelerator complex, and by exciting their atomic degrees of freedom with lasers to produce…
The detection of very-high-energy (VHE; $>$100 GeV) $\gamma$-ray radiation from misaligned jetted Active Galactic Nuclei (AGN) challenges the emission models that primarily explain VHE emissions from beamed AGN, i.e., blazars. Using over 16…