Positronium imaging with the novel multiphoton PET scanner
Abstract
In vivo assessment of cancer and precise location of altered tissues at initial stages of molecular disorders are important diagnostic challenges. Positronium is copiously formed in the free molecular spaces in the patient's body during positron emission tomography (PET). The positronium properties vary according to the size of inter- and intramolecular voids and the concentration of molecules in them such as, e.g., molecular oxygen, O2; therefore, positronium imaging may provide information about disease progression during the initial stages of molecular alterations. Current PET systems do not allow acquisition of positronium images. This study presents a new method that enables positronium imaging by simultaneous registration of annihilation photons and deexcitation photons from pharmaceuticals labeled with radionuclides. The first positronium imaging of a phantom built from cardiac myxoma and adipose tissue is demonstrated. It is anticipated that positronium imaging will substantially enhance the specificity of PET diagnostics.
Cite
@article{arxiv.2112.08741,
title = {Positronium imaging with the novel multiphoton PET scanner},
author = {Paweł Moskal and Kamil Dulski and Neha Chug and Catalina Curceanu and Eryk Czerwiński and Meysam Dadgar and Jan Gajewski and Aleksander Gajos and Grzegorz Grudzień and Beatrix C. Hiesmayr and Krzysztof Kacprzak and Łukasz Kapłon and Hanieh Karimi and Konrad Klimaszewski and Grzegorz Korcyl and Paweł Kowalski and Tomasz Kozik and Nikodem Krawczyk and Wojciech Krzemień and Ewelina Kubicz and Piotr Małczak and Szymon Niedźwiecki and Monika Pawlik-Niedźwiecka and Michał Pędziwiatr and Lech Raczyński and Juhi Raj and Antoni Ruciński and Sushil Sharma and Shivani and Roman Y. Shopa and Michał Silarski and Magdalena Skurzok and Ewa Ł. Stępień and Monika Szczepanek and Faranak Tayefi and Wojciech Wiślicki},
journal= {arXiv preprint arXiv:2112.08741},
year = {2021}
}
Comments
10 pages, 5 figures