PET is a functional imaging technique based on detection of annihilation photons following beta decay producing positrons. In this paper, we present the concept of a new PET system for preclinical applications consisting of a ring of twelve time projection chambers filled with liquid xenon viewed by avalanche photodiodes. Simultaneous measurement of ionization charge and scintillation light leads to a significant improvement to spatial resolution, image quality, and sensitivity. Simulated performance shows that an energy resolution of <10% (FWHM) and a sensitivity of 15% are achievable. First tests with a prototype TPC indicate position resolution <1 mm (FWHM).
@article{arxiv.1104.1458,
title = {Liquid Xenon Detectors for Positron Emission Tomography},
author = {A. Miceli and P. Amaudruz and F. Benard and D. A. Bryman and L. Kurchaninov and J. P. Martin and A. Muennich and F. Retiere and T. J. Ruth and V. Sossi and A. J. Stoessl},
journal= {arXiv preprint arXiv:1104.1458},
year = {2015}
}
Comments
Paper presented at the International Nuclear Physics Conference, Vancouver, Canada, 2010