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The biological function of membranes is closely related to their softness, which is often studied through the membranes' thermally-driven fluctuations. The analysis commonly assumes that the relaxation rate of a pure bending deformation is…

Soft Condensed Matter · Physics 2024-07-09 Hammad A. Faizi , Rony Granek , Petia M. Vlahovska

The effect of AC electric fields on the elasticity of supported lipid bilayers has been investigated at the microscopic level using grazing incidence synchrotron x-ray scattering. A strong decrease in the membrane tension up to 1mN/m and a…

Soft Condensed Matter · Physics 2016-06-08 Arnaud Hemmerle , Thierry Charitat , Giovanna Fragneto , Jean Daillant

Amphiphilic lipid bilayers modify the friction properties of the surfaces on top of which they are deposited. In particular, the measured sliding friction coefficient is significantly reduced compared with the native surface. We investigate…

Biological Physics · Physics 2021-12-01 Othmène Benazieb , Claire Loison , Fabrice Thalmann

We have adapted a set of classification algorithms, also known as Machine Learning, to the identification of fluid and gel domains close to the main transition of dipalmitoyl-phosphatidylcholine (DPPC) bilayers. Using atomistic molecular…

Soft Condensed Matter · Physics 2023-07-19 Viven Walter , Céline Ruscher , Olivier Benzerara , Carlos M. Marques , Fabrice Thalmann

An accurate description of the structure and dynamics of interfacial water is essential for phospholipid membranes, since it determines their function and their interaction with other molecules. Here we consider water confined in stacked…

Soft Condensed Matter · Physics 2018-11-16 Sotiris Samatas , Carles Calero , Fausto Martelli , Giancarlo Franzese

We study the influence of truncating the electrostatic interactions in a fully hydrated pure dipalmitoylphosphatidylcholine (DPPC) bilayer through 20 ns molecular dynamics simulations. The computations in which the electrostatic…

Soft Condensed Matter · Physics 2009-11-07 M. Patra , M. Karttunen , M. Hyvonen , E. Falck , P. Lindqvist , I. Vattulainen

We consider the hydrodynamics of lipid bilayers containing transmembrane proteins of arbitrary shape. This biologically-motivated problem is relevant to the cell membrane, whose fluctuating dynamics play a key role in phenomena ranging from…

Soft Condensed Matter · Physics 2016-10-10 Andrew Callan-Jones , Marc Durand , Jean-Baptiste Fournier

Water-phospholipid interactions at the lipid bilayer/water interfaces are of essential importance for the dynamics, stability and function of biological membrane, and are also strongly associated with numerous biological processes at the…

Soft Condensed Matter · Physics 2018-01-04 Jianjun Jiang , Weixin Li , Liang Zhao , Yuanyan Wu , Peng Xiu , Guoning Tang , Yusong Tu

The response kinetics of liquid crystalline phosphatidylcholine bilayer stacks to rapid, IR-laser induced temperature jumps has been studied by millisecond time-resolved x-ray diffraction. The system reacts on the fast temperature change by…

Biological Physics · Physics 2007-05-23 Georg Pabst , Michael Rappolt , Heinz Amenitsch , Sigrid Bernstorff , Peter Laggner

With the aim of establishing a criterion for identifying when a lipid bilayer has reached steady state using the molecular dynamics simulation technique, lipid bilayers of different composition in their liquid crystalline phase were…

Soft Condensed Matter · Physics 2012-12-13 Rodolfo D. Porasso , José J. López Cascales

Biological membranes are known to form various structural motifs, from lipid bilayers to tubular filaments and networks facilitating e.g. adhesion and cell-cell communication. To understand the biophysical processes underpinning lipid-lipid…

Soft Condensed Matter · Physics 2025-12-30 David Regan , Paola Borri , Wolfgang Langbein

A new method is proposed for the analysis of specular and off-specular reflectivity from supported lipid bilayers. Both thermal fluctuations and the "static" roughness induced by the substrate are carefully taken into account. Examples from…

Soft Condensed Matter · Physics 2009-10-08 Linda Malaquin , Thierry Charitat , Jean Daillant

Understanding dynamic and complex interaction of biological membranes with extracellular matrices plays a crucial role in controlling a variety of cell behavior and functions, from cell adhesion and growth to signaling and differentiation.…

Soft Condensed Matter · Physics 2022-07-28 Selcan Karaz , Mertcan Han , Gizem Akay , Asim Onal , Sedat Nizamoglu , Seda Kizilel , Erkan Senses

Lipid membranes form the barrier between the inside and outside of cells and many of their subcompartments. As such, they bind to a wide variety of nano- and micrometer sized objects and, in the presence of strong adhesive forces, strongly…

Soft Condensed Matter · Physics 2021-08-31 Hendrik T. Spanke , Jaime Agudo-Canalejo , Daniel Tran , Robert W. Style , Eric R. Dufresne

We study, using dissipative particle dynamics simulations, the effect of active lipid flip-flop on model fluid bilayer membranes. We consider both cases of symmetric as well as asymmetric flip-flops. Symmetric flip-flop leads to a steady…

Soft Condensed Matter · Physics 2009-11-13 Sanoop Ramachandran , P. B. Sunil Kumar , Mohamed Laradji

The statistical physics and dynamics of double supported bilayers are studied theoretically. The main goal in designing double supported lipid bilayers is to obtain model systems of biomembranes: the upper bilayer is meant to be almost…

Soft Condensed Matter · Physics 2015-03-13 Manoel Manghi , Nicolas Destainville

We theoretically investigate the dynamics of a floating lipid bilayer membrane coupled with a two-dimensional cytoskeleton network, taking into explicitly account the intermonolayer friction, the discrete lattice structure of the…

Soft Condensed Matter · Physics 2017-08-02 Ryuichi Okamoto , Shigeyuki Komura , Jean-Baptiste Fournier

On the basis of the separated form-factor model, a code for fitting the small-angle neutron scattering spectra of the polydispersed vesicle population has been developed. Vesicle and membrane bilayer parameters are analyzed for various…

Chemical Physics · Physics 2007-05-23 E. V. Zemlyanaya , M. A. Kiselev , V. K. Aswal

We report a combined dynamic light scattering and neutron spin-echo (NSE) study on vesicles composed of the phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine under the influence of varying amounts of perfluorooctanoic acid. We…

Soft Condensed Matter · Physics 2014-05-06 Beate-Annette Bruening , Bela Farago

Viscosity is a key property of cell membranes that controls mobility of embedded proteins and membrane remodeling. Measuring it is challenging because existing approaches involve complex experimental designs and/or models, and the…

Soft Condensed Matter · Physics 2023-07-19 Hammad A. Faizi , Rumiana Dimova , Petia M. Vlahovska