Perfluorooctanoic acid rigidifies a model lipid membrane

Beate-Annette Bruening; Bela Farago

doi:10.1103/PhysRevE.89.040702

Perfluorooctanoic acid rigidifies a model lipid membrane

Soft Condensed Matter 2014-05-06 v1

Authors: Beate-Annette Bruening , Bela Farago

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Abstract

We report a combined dynamic light scattering and neutron spin-echo (NSE) study on vesicles composed of the phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine under the influence of varying amounts of perfluorooctanoic acid. We study local lipid bilayer undulations using NSE on time scales up to 200 ns. Similar to the effect evoked by cholesterol, we attribute the observed lipid bilayer stiffening to a condensing effect of the perfluorinated compound on the membrane.

Cite

@article{arxiv.1405.0845,
  title  = {Perfluorooctanoic acid rigidifies a model lipid membrane},
  author = {Beate-Annette Bruening and Bela Farago},
  journal= {arXiv preprint arXiv:1405.0845},
  year   = {2014}
}

Comments

5 pages, 4 figures

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