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Purpose: To evaluate automated multicriteria optimization (MCO)-- designed for intensity modulated radiation therapy (IMRT), but invoked with limited segmentation -- to efficiently produce high quality 3D conformal treatment (3D-CRT) plans.…

Medical Physics · Physics 2014-02-03 Fazal Khan , David Craft

We present a conjugate-gradient method for the ground-state optimization of projected entangled-pair states (PEPS) in the thermodynamic limit, as a direct implementation of the variational principle within the PEPS manifold. Our…

Strongly Correlated Electrons · Physics 2016-11-08 Laurens Vanderstraeten , Jutho Haegeman , Philippe Corboz , Frank Verstraete

Dose volume histograms are a useful tool in state-of-the-art radiotherapy planning, and it is essential to be aware of their limitations. Dose distributions computed by treatment planning systems are affected by several sources of…

Medical Physics · Physics 2007-06-13 Francisco Cutanda-Henriquez , Silvia Vargas-Castrillon

The kinematics of a gliding flat-plate with spanwise oscillation has been optimized to enhance the power efficiency by using Bayesian optimization method, in which the portfolio allocation framework consists of a Gaussian process…

Fluid Dynamics · Physics 2021-09-10 Chunyu Wang , Zhaoyue Xu , Xinlei Zhang , Shizhao Wang

Nuclear fusion using magnetic confinement holds promise as a viable method for sustainable energy. However, most fusion devices have been experimental and as we move towards energy reactors, we are entering into a new paradigm of…

Plasma Physics · Physics 2023-10-04 Timothy Nunn , Vignesh Gopakumar , Sebastien Kahn

In this paper, we propose a shape optimization pipeline for propeller blades, applied to naval applications. The geometrical features of a blade are exploited to parametrize it, allowing to obtain deformed blades by perturbating their…

Optimization and Control · Mathematics 2024-01-17 Anna Ivagnes , Nicola Demo , Gianluigi Rozza

Gas turbine engines are highly efficient and powerful because of their high-pressure turbines (HPTs). Furthermore, stationary blades shape and prepare high-pressure gas for efficient utilization by moving blades. Consequently, optimizing…

Fluid Dynamics · Physics 2024-01-05 Seyed Ehsan Hosseini , Saeid Jafaripanah , Zoheir Saboohi

The increasing availability of structured but high dimensional data has opened new opportunities for optimization. One emerging and promising avenue is the exploration of unsupervised methods for projecting structured high dimensional data…

Machine Learning · Computer Science 2021-01-07 Eero Siivola , Javier Gonzalez , Andrei Paleyes , Aki Vehtari

A multiobjective optimization method is proposed for obtaining the optimal plane trusses simultaneously for various aspect ratios of the initial ground structure as a set of Pareto optimal solutions generated through a single optimization…

Optimization and Control · Mathematics 2023-08-01 Makoto Ohsaki , Saku Aoyagi , Kazuki Hayashi

We examine the interaction of multigrid methods and shape optimization in appropriate shape spaces. Our aim is a scalable algorithm for application on supercomputers, which can only be achieved by mesh-independent convergence. The impact of…

Optimization and Control · Mathematics 2021-04-12 Martin Siebenborn , Kathrin Welker

This study presents a shape optimization framework that combines a Flux Reconstruction (FR) spatial discretization, Large Eddy Simulation (LES), the Ffowcs-Williams and Hawkings (FW-H) formulation, and the gradient-free Mesh Adaptive Direct…

Fluid Dynamics · Physics 2025-10-14 Mohsen Hamedi , Brian Vermeire

Purpose: We present a framework for robust automated treatment planning using machine learning, comprising scenario-specific dose prediction and robust dose mimicking. Methods: The scenario dose prediction pipeline is divided into the…

Medical Physics · Physics 2022-10-12 Oskar Eriksson , Tianfang Zhang

An introduction to the application of combinatorial optimization methods to ground state calculations of frustrated, disordered systems is given. We discuss the interface problem in the random bond Ising ferromagnet, the random field Ising…

Disordered Systems and Neural Networks · Physics 2009-10-30 H. Rieger

We present a general mathematical framework for optimizing cell deployment and antenna configuration in wireless networks, inspired by quantization theory. Unlike traditional methods, our framework supports networks with deterministically…

Information Theory · Computer Science 2025-02-04 Saeed Karimi-Bidhendi , Giovanni Geraci , Hamid Jafarkhani

A statistical volumetric model, showing the probability map of localized prostate cancer within the host anatomical structure, has been developed from 90 optically-imaged surgical specimens. This master model permits an accurate…

Quantitative Methods · Quantitative Biology 2014-09-16 Liang Zhao , Jianhua Xuan , Yue Wang

To make full use of photocathode material and improve its quantum efficiency lifetime, it can be necessary to operate laser away from the cathode center in photoinjectors. In RF guns, the off-axis emitted beam will see a time-dependent RF…

Accelerator Physics · Physics 2016-12-21 Rui-Xuan Huang , Chad Mitchell , Qi-Ka Jia , Christos Papadopoulos , Fernando Sannibale

Treatment planning uncertainties are typically managed using margin-based or robust optimization. Margin-based methods expand the clinical target volume (CTV) to a planning target volume, generally unsuited for proton therapy. Robust…

Whole gland (WG) segmentation of the prostate plays a crucial role in detection, staging and treatment planning of prostate cancer (PCa). Despite promise shown by deep learning (DL) methods, they rely on the availability of a considerable…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Alvaro Fernandez-Quilez , Steinar Valle Larsen , Morten Goodwin , Thor Ole Gulsurd , Svein Reidar Kjosavik , Ketil Oppedal

Due to fundamental limitations on terrestrial quantum links, satellites have received considerable attention for their potential as entanglement generation sources in a global quantum internet. In this work, we focus on the problem of…

Quantum Physics · Physics 2026-03-04 Athul Ashok , Owen DePoint , Jackson MacDonald , Albert Williams , Don Towsley

In this chapter, we investigate recently proposed nonlinear conjugate gradient (NCG) methods for shape optimization problems. We briefly introduce the methods as well as the corresponding theoretical background and investigate their…

Optimization and Control · Mathematics 2025-10-14 Sebastian Blauth
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