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In optical metrology, grating-like structures are used as tools to evaluate the performance of lithographic techniques. In particular, several shape parameters characterize those structures. One of them, termed side-wall angle, suffers from…

Optics · Physics 2015-10-21 Luca Cisotto , Paul H. Urbach

Intensity Modulated Radiation Therapy is an effective cancer treatment. Models based on the Generalized Equivalent Uniform Dose (gEUD) provide radiation plans with excellent planning target volume coverage and low radiation for organs at…

Background: Spectral shaping is a computed tomography (CT) dose optimization technique that adjusts source voltage and filtration to reduce patient radiation exposure without compromising image quality. Traditionally, radiation dose has…

Particle based optimization algorithms have recently been developed as sampling methods that iteratively update a set of particles to approximate a target distribution. In particular Stein variational gradient descent has gained attention…

Machine Learning · Computer Science 2021-03-19 Francesco D'Angelo , Vincent Fortuin

With many variables to adjust, conventional manual forward planning for Gamma Knife (GK) radiosurgery is very complicated and cumbersome. The resulting plan quality heavily depends on planners skills, experiences and devoted efforts, and…

The relative smoothing rates of various gauge field smoothing algorithms are investigated on ${\cal O}(a^2)$-improved $\suthree$ Yang--Mills gauge field configurations. In particular, an ${\cal O}(a^2)$-improved version of APE smearing is…

High Energy Physics - Lattice · Physics 2010-03-04 Frederic D. R. Bonnet , Derek B. Leinweber , Anthony G. Williams , James M. Zanotti

Improving the power output from wind farms is vital in transitioning to renewable electricity generation. However, in wind farms, wind turbines often operate in the wake of other turbines, leading to a reduction in the wind speed and the…

Fluid Dynamics · Physics 2024-07-31 Andrew Mole , Sylvain Laizet

Coarse-grained (CG) force field models are extensively utilised in material simulations due to their scalability. Traditionally, these models are parameterized using hybrid strategies that integrate top-down and bottom-up approaches;…

Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…

Medical Physics · Physics 2023-12-05 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Chemical plant design and optimisation have proven challenging due to the complexity of these real-world systems. The resulting complexity translates into high computational costs for these systems' mathematical formulations and simulation…

Neural and Evolutionary Computing · Computer Science 2022-04-28 Liezl Stander , Matthew Woolway , Terence L. Van Zyl

Gradient-based optimization of engineering designs is limited by non-differentiable components in the typical computer-aided engineering (CAE) workflow, which calculates performance metrics from design parameters. While gradient-based…

Computational Engineering, Finance, and Science · Computer Science 2025-11-17 Andrin Rehmann , Nolan Black , Josiah Bjorgaard , Alessandro Angioi , Andrei Paleyes , Niklas Heim , Dion Häfner , Alexander Lavin

This work suggests to optimize the geometry of a quadrupole magnet by means of a genetic algorithm adapted to solve multi-objective optimization problems. To that end, a non-domination sorting genetic algorithm known as NSGA-III is used.…

Hybrid magnetic shields with both active field generating components and high-permeability magnetic shielding are increasingly needed for a variety of technologies and experiments that require precision-controlled magnetic field…

Applied Physics · Physics 2021-06-04 M. Packer , P. J. Hobson , N. Holmes , J. Leggett , P. Glover , M. J. Brookes , R. Bowtell , T. M. Fromhold

Radiation therapy treatment planning can be viewed as an iterative hyperparameter tuning process to balance conflicting clinical goals. In this work, we investigated the performance of modern Bayesian Optimization (BO) methods on automated…

Medical Physics · Physics 2023-02-15 Qingying Wang , Ruoxi Wang , Jiacheng Liu , Fan Jiang , Haizhen Yue , Yi Du , Hao Wu

Designs generated by density-based topology optimization (TO) exhibit jagged and/or smeared boundaries, which forms an obstacle to their integration with existing CAD tools. Addressing this problem by smoothing or manual design adjustments…

Computational Engineering, Finance, and Science · Computer Science 2020-04-14 Marco K. Swierstra , Deepak K. Gupta , Matthijs Langelaar

One of the grand challenges in intensity-modulated radiotherapy (IMRT) planning is to optimize the beam angles in a reasonable computation time. To demonstrate the value of prior knowledge on improving the efficiency of beam angle…

Medical Physics · Physics 2018-11-06 Yong-Jie Li

A method to design gratings in integrated photonics, is presented. The method is based on a transfer matrix formalism enhanced by Finite Element Method (FEM) parameter calculations. The main advantages of the proposed technique are the easy…

Optics · Physics 2021-06-14 Clara Zaccaria , Mattia Mancinelli , Lorenzo Pavesi

A central challenge in the design of energy-efficient wind farms is the presence of wake effects between turbines. When a wind turbine harvests energy from free wind, it produces a turbulent region with reduced energy for downstream…

Optimization and Control · Mathematics 2025-12-24 James Kotary , Natalie Isenberg , Draguna Vrabie

We present a volumetric mesh-based algorithm for parameterizing the placenta to a flattened template to enable effective visualization of local anatomy and function. MRI shows potential as a research tool as it provides signals directly…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 S. Mazdak Abulnaga , Esra Abaci Turk , Mikhail Bessmeltsev , P. Ellen Grant , Justin Solomon , Polina Golland

Treatment planning in low-dose-rate prostate brachytherapy (LDR-PB) aims to produce arrangement of implantable radioactive seeds that deliver a minimum prescribed dose to the prostate whilst minimizing toxicity to healthy tissues. There can…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Tajwar Abrar Aleef , Ingrid T. Spadinger , Michael D. Peacock , Septimiu E. Salcudean , S. Sara Mahdavi