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Biological organisms have evolved a wide range of immune mechanisms to defend themselves against pathogens. Beyond molecular details, these mechanisms differ in how protection is acquired, processed and passed on to subsequent generations…

Populations and Evolution · Quantitative Biology 2016-12-26 Andreas Mayer , Thierry Mora , Olivier Rivoire , Aleksandra M. Walczak

We develop an anomaly-detection method when systematic anomalies, possibly statistically very similar to genuine inputs, are affecting control systems at the input and/or output stages. The method allows anomaly-free inputs (i.e., those…

Methodology · Statistics 2022-02-01 Ning Sun , Chen Yang , Ričardas Zitikis

The evolving landscape of electric power networks, influenced by the integration of distributed energy resources require the development of novel power system monitoring and control architectures. This paper develops algorithm to monitor…

Systems and Control · Electrical Eng. & Systems 2024-12-05 Erfan Mehdipour Abadi , Masoud H. Nazari

The physical interpretation of the functioning of the adaptive immune system, which has been thoroughly characterized on genetic and molecular levels, provides a unique opportunity to define an adaptive self-organizing biological system in…

Molecular Networks · Quantitative Biology 2023-05-19 Jozsef Prechl

In this thesis, the uses of Artificial Immune Systems (AIS) in Machine learning is studded. the thesis focus on some of immune inspired algorithms such as clonal selection algorithm and artificial immune network. The effect of changing the…

Neural and Evolutionary Computing · Computer Science 2017-09-14 Mohammad Tarek Al Muallim

Organ-on-a-chip (OoCs) platforms could revolutionize drug discovery and might ultimately become essential tools for precision therapy. Although many single-organ and interconnected systems have been described, the immune system has been…

We consider the problem of designing synthetic cells to achieve a complex goal (e.g., mimicking the immune system by seeking invaders) in a complex environment (e.g., the circulatory system), where they might have to change their control…

Robotics · Computer Science 2020-03-10 Ana Pervan , Todd Murphey

In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems. A number of key general properties…

Artificial Intelligence · Computer Science 2016-11-17 Jamie Twycross , Uwe Aickelin

Machine learning and data mining algorithms play important roles in designing intrusion detection systems. Based on their approaches toward the detection of attacks in a network, intrusion detection systems can be broadly categorized into…

Cryptography and Security · Computer Science 2020-09-16 Jaydip Sen , Sidra Mehtab

The clonal selection principle explains the basic features of an adaptive immune response to a antigenic stimulus. It established the idea that only those cells that recognize the antigens are selected to proliferate and differentiate. This…

Neural and Evolutionary Computing · Computer Science 2018-04-10 Takumi Ichimura , Shin Kamada

Biological and artificial networks routinely make reliable distinctions between similar inputs, and the rules for making these distinctions are learned. In some ways, self/nonself discrimination in the immune system is similar, being both…

Over the last few years, more and more heuristic decision making techniques have been inspired by nature, e.g. evolutionary algorithms, ant colony optimisation and simulated annealing. More recently, a novel computational intelligence…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin

In the research area of anomaly detection, novel and promising methods are frequently developed. However, most existing studies exclusively focus on the detection task only and ignore the interpretability of the underlying models as well as…

Machine Learning · Computer Science 2023-01-16 Cheng Feng , Pingge Hu

We apply several machine learning algorithms to the problem of anomaly detection in operational data for large-scale, high-voltage electric power grids. We observe important differences in the performance of the algorithms. Neural networks…

Systems and Control · Electrical Eng. & Systems 2026-02-12 Marc Gillioz , Guillaume Dubuis , Étienne Voutaz , Philippe Jacquod

Artificial neural networks are being proposed as models of parts of the brain. The networks are compared to recordings of biological neurons, and good performance in reproducing neural responses is considered to support the model's…

Neurons and Cognition · Quantitative Biology 2023-09-01 Yena Han , Tomaso Poggio , Brian Cheung

We consider the mutual interactions, via cytokine exchanges, among helper lymphocytes, B lymphocytes and killer lymphocytes, and we model them as a unique system by means of a tripartite network. Each part includes all the different clones…

Biological Physics · Physics 2015-03-19 Elena Agliari , Adriano Barra , Francesco Guerra , Francesco Moauro

In the modern world, we are permanently using, leveraging, interacting with, and relying upon systems of ever higher sophistication, ranging from our cars, recommender systems in e-commerce, and networks when we go online, to integrated…

Artificial Intelligence · Computer Science 2023-06-23 Patrick Rodler

The immune response to a pathogen has two basic features. The first is the expansion of a few pathogen-specific cells to form a population large enough to control the pathogen. The second is the process of differentiation of cells from an…

Populations and Evolution · Quantitative Biology 2014-02-04 Sean P Stromberg , Rustom Antia , Ilya Nemenman

Several abilities of biological systems, such as adaptation to natural environment, or of animals to learn patterns when appropriately trained, are features that are extremely useful, if emulated by electronic circuits, in applications…

Neurons and Cognition · Quantitative Biology 2011-12-22 M. Di Ventra , Y. V. Pershin

Digitalization in the medical world provides major benefits while making it a target for attackers and thus hard to secure. To deal with network intruders we propose an anomaly detection system on hardware to detect malicious clients in…

Cryptography and Security · Computer Science 2025-06-19 Florian Rokohl , Alexander Lehnert , Marc Reichenbach
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