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Related papers: Polymer translocation through a nanopore under a p…

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We study the translocation of a flexible polymer through extended patterned pores using molecular dynamics (MD) simulations. We consider cylindrical and conical pore geometries that can be controlled by the angle of the pore apex $\alpha$.…

Soft Condensed Matter · Physics 2026-02-11 Andri Sharma , Abhishek Chaudhuri , Rajeev Kapri

We study the driven translocation of a flexible polymer through an interacting conical pore using Langevin dynamics simulations. We find that, for a fixed value of externally applied force and pore polymer interaction strength, the mean…

Soft Condensed Matter · Physics 2021-02-17 Rajneesh Kumar , Abhishek Chaudhuri , Rajeev Kapri

Brownian dynamics (BD) simulations are used to study the translocation dynamics of a coarse-grained polymer through a cylindrical nanopore. We consider the case of short polymers, with a polymer length, N, in the range N=21-61. The rate of…

Soft Condensed Matter · Physics 2015-06-18 James M. Polson , Taylor Dunn

We study the translocation dynamics of a polymer chain threaded through a nanopore by an external force. By means of diverse methods (scaling arguments, fractional calculus and Monte Carlo simulation) we show that the relevant dynamic…

Statistical Mechanics · Physics 2007-07-29 J. L. A. Dubbeldam , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

We use a combination of computer simulations and iso-flux tension propagation (IFTP) theory to investigate translocation dynamics of a flexible linear polymer through a nanopore into an environment composed of repulsive active rods in 2D.…

Soft Condensed Matter · Physics 2021-02-03 Hamidreza Khalilian , Jalal Sarabadani , Tapio Ala-Nissila

Most of the theoretical models describing the translocation of a polymer chain through a nanopore use the hypothesis that the polymer is always relaxed during the complete process. In other words, models generally assume that the…

Biomolecules · Quantitative Biology 2009-11-13 Michel G. Gauthier , Gary W. Slater

Using Langevin dynamics simulations, we investigate the dynamics of chaperone-assisted translocation of a flexible polymer through a nanopore. We find that increasing the binding energy $\epsilon$ between the chaperone and the chain and the…

Soft Condensed Matter · Physics 2011-08-26 Wancheng Yu , Kaifu Luo

Polymer translocation through a nanopore in a membrane investigated theoretically. Recent experiments on voltage-driven DNA and RNA translocations through a nanopore indicate that the size and geometry of the pore are important factors in…

Statistical Mechanics · Physics 2009-11-07 Elena Slonkina , Anatoly B. Kolomeisky

We study pore blockade times for a translocating polymer of length $N$, driven by a field $E$ across the pore in three dimensions. The polymer performs Rouse dynamics, i.e., we consider polymer dynamics in the absence of hydrodynamical…

Soft Condensed Matter · Physics 2008-02-15 Henk Vocks , Debabrata Panja , Gerard T. Barkema , Robin C. Ball

We consider a polymer of length $N$ translocating through a narrow pore in the absence of external fields. Characterization of its purportedly anomalous dynamics has so far remained incomplete. We show that the polymer dynamics is anomalous…

Soft Condensed Matter · Physics 2007-10-08 Debabrata Panja , Gerard T. Barkema , Robin C. Ball

We investigate several scaling properties of a translocating homopolymer through a thin pore driven by an external field present inside the pore only using Langevin Dynamics (LD) simulation in three dimension (3D). Specifically motivated by…

In forced polymer translocation, the average translocation time, $\tau$, scales with respect to pore force, $f$, and polymer length, $N$, as $\tau \sim f^{-1} N^{\beta}$. We demonstrate that an artifact in Metropolis Monte Carlo method…

Biological Physics · Physics 2009-11-13 V. V. Lehtola , R. P. Linna , K. Kaski

The transport of polymers with folded configurations across membrane pores is investigated theoretically by analyzing simple discrete stochastic models. The translocation dynamics is viewed as a sequence of two events: motion of the folded…

Statistical Mechanics · Physics 2009-11-13 Stanislav Kotsev , Anatoly B. Kolomeisky

In this paper, we investigate the microscopic dynamics of a polymer of length $N$ translocating through a narrow pore. Characterization of its purportedly anomalous dynamics has so far remained incomplete. We show that the polymer dynamics…

Soft Condensed Matter · Physics 2007-07-25 Debabrata Panja , Gerard T. Barkema , Robin C. Ball

We present event distributions for the polymer translocation obtained by extensive Langevin dynamics simulations. Such distributions have not been reported previously and they provide new understanding of the stochastic characteristics of…

Soft Condensed Matter · Physics 2012-04-13 R. P. Linna , K. Kaski

We investigate the influence of polymer-pore interactions on the translocation dynamics using Langevin dynamics simulations. An attractive interaction can greatly improve translocation probability. At the same time, it also increases…

Soft Condensed Matter · Physics 2007-10-01 Kaifu Luo , Tapio Ala-Nissila , See-chen Ying , Aniket Bhattacharya

The impact of thermal fluctuations on the translocation dynamics of a polymer chain driven through a narrow pore has been investigated theoretically and by means of extensive Molecular-Dynamics (MD) simulation. The theoretical consideration…

Soft Condensed Matter · Physics 2015-06-12 J. L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

We perform two-dimensional Langevin dynamics simulations of electric-field driven polymer translocation through an attractive nanopore. We investigate the effect of the location of the attractive region using different pore patterns. This…

Soft Condensed Matter · Physics 2015-06-15 F Piguet , D P Foster

We consider the passage of long polymers of length N through a hole in a membrane. If the process is slow, it is in principle possible to focus on the dynamics of the number of monomers s on one side of the membrane, assuming that the two…

Soft Condensed Matter · Physics 2009-11-10 Yacov Kantor , Mehran Kardar

Using Langevin dynamics simulations in three dimensions (3D), we investigate the dynamics of polymer translocation into the regions between two parallel plane walls with separation $R$ under a driving force $F$, respectively. Compared with…

Soft Condensed Matter · Physics 2010-08-18 Kaifu Luo , Ralf Metzler