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The effect of heterogeneous sequence composition on the denaturation of double stranded DNA is investigated. The resulting pair-binding energy variation is found to have a negligible effect on the critical properties of the smooth second…

Statistical Mechanics · Physics 2009-10-30 D. Cule , T. Hwa

As the periodicity in crystalline materials creates the optimal condition for electronic delocalization, one might expect that in partially crystalline conjugated polymers delocalization is impeded by intergrain transport. However, for the…

Materials Science · Physics 2009-11-10 H. C. F. Martens , H. B. Brom

We present an analysis of a system of weakly coupled Hubbard chains based on combining an exact study of spectral functions of the uncoupled chain system with a renormalization group method for the coupled chains. For low values of the…

Strongly Correlated Electrons · Physics 2009-11-10 J. M. P. Carmelo , F. Guinea , K. Penc , P. D. Sacramento

We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand. To preserve this structural invariant, we impose…

Logic in Computer Science · Computer Science 2010-06-16 Luca Cardelli

A DNA-protein complex modelled by a semiflexible chain and an attractive spherical core is studied in the situation when an external stretching force is acting on one end monomer of the chain while the other end monomer is kept fixed in…

Soft Condensed Matter · Physics 2009-11-10 Takahiro Sakaue , Hartmut Löwen

The genetic information that dictates the structure and function of all life forms is encoded in the DNA. In 1953, Watson and Crick first presented the double helical structure of a DNA molecule. Their findings unearthed the desire to…

Genomics · Quantitative Biology 2023-05-16 Olaitan Akintunde , Trichina Tucker , Valerie J. Carabetta

While stretching of most polymer chains leads to rather featureless force-extension diagrams, some, notably DNA, exhibit non-trivial behavior with a distinct plateau region. Here we propose a unified theory that connects force-extension…

Mesoscale and Nanoscale Physics · Physics 2013-02-26 Alexander V. Savin , Mikhail A. Mazo , Irina P. Kikot , Alexey V. Onufriev

Because of the double-helical structure of DNA, in which two strands of complementary nucleotides intertwine around each other, a covalently closed DNA molecule with no interruptions in either strand can be viewed as two interlocked…

Biomolecules · Quantitative Biology 2015-05-13 Lauren A. Britton , Wilma K. Olson , Irwin Tobias

The question of whether DNA conducts electric charges is intriguing to physicists and biologists alike. The suggestion that electron transfer/transport in DNA might be biologically important has triggered a series of experimental and…

Disordered Systems and Neural Networks · Physics 2020-05-04 H. Wang , R. Marsh , J. P. Lewis , R. A. Roemer

The random-dimer model is probably the most popular model for a one-dimensional disordered system where correlations are responsible for delocalization of the wave functions. This is the primary model used to justify the insulator-metal…

Quantum Gases · Physics 2010-04-27 Jean-François Schaff , Zehra Akdeniz , Patrizia Vignolo

Sequencing by tunneling is a next-generation approach to read single-base information using electronic tunneling transverse to the single-stranded DNA (ssDNA) backbone while the latter is translocated through a narrow channel. The original…

Soft Condensed Matter · Physics 2015-09-23 P. Boynton , A. V. Balatsky , I. K. Schuller , M. Di Ventra

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex…

Other Quantitative Biology · Quantitative Biology 2014-03-12 Jian-Jun Shu , Li Shan Ouw

We study an intermediate quantum coherent-incoherent charge transport mechanism in metal-molecule-metal junctions using B\"uttiker's probe technique. This tool allows us to include incoherent effects in a controlled manner, and thus to…

Mesoscale and Nanoscale Physics · Physics 2017-04-12 Hyehwang Kim , Michael Kilgour , Dvira Segal

Microscopic mechanisms of positive charge transfer in DNA remain unclear. A quantum state of electron hole in DNA is determined by the competition of the pi-stacking interaction $b$ sharing a charge between different base pairs and the…

Soft Condensed Matter · Physics 2008-06-06 Dmitry B. Uskov , Alexander L. Burin

By exploring a recent model [Palmeri, J., M. Manghi, and N. Destainville. 2007. Phys. Rev. Lett. 99:088103] where DNA bending elasticity, described by the wormlike chain model, is coupled to base-pair denaturation, we demonstrate that small…

Statistical Mechanics · Physics 2010-06-22 Nicolas Destainville , Manoel Manghi , John Palmeri

The detection of similarities between long DNA and protein sequences is studied using concepts of statistical physics. It is shown that mutual similarities can be detected by sequence alignment methods only if their amount exceeds a…

Condensed Matter · Physics 2009-10-28 Terence Hwa , Michael Lassig

A double--layer system in a strong perpendicular magnetic field is considered. We assume a random potential in each layer to be smooth. We also assume that there is no correlation between random potentials in different layers. Under these…

Condensed Matter · Physics 2009-10-28 A. Gramada , M. E. Raikh

We investigate quantum transport characteristics of a ladder model, which effectively mimics the topology of a double-stranded DNA molecule. We consider the interaction of tunneling charges with a selected internal vibrational degree of…

Soft Condensed Matter · Physics 2007-05-23 R. Gutierrez , S. Mohapatra , H. Cohen , D. Porath , G. Cuniberti

Cryptography is the science that secures data and communication over the network by applying mathematics and logic to design strong encryption methods. In the modern era of e-business and e-commerce the protection of confidentiality,…

Cryptography and Security · Computer Science 2023-08-07 Mandrita Mondal , Kumar S. Ray

DNA has immense potential as an emerging data storage medium. The principle of DNA storage is the conversion and flow of digital information between binary code stream, quaternary base, and actual DNA fragments. This process will inevitably…

Information Retrieval · Computer Science 2022-10-21 Yun Qin , Fei Zhu , Bo Xi
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