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As key elements within the central dogma, DNA, RNA, and proteins play crucial roles in maintaining life by guaranteeing accurate genetic expression and implementation. Although research on these molecules has profoundly impacted fields like…

Task load detection is essential for optimizing human performance across diverse applications, yet current models often lack generalizability beyond narrow experimental domains. While prior research has focused on individual tasks and…

Machine Learning · Computer Science 2025-09-03 Maximilian P. Oppelt , Andreas Foltyn , Nadine R. Lang-Richter , Bjoern M. Eskofier

Tabular foundation models such as TabPFN and TabICL already produce full predictive distributions, yet prevailing regression benchmarks evaluate them almost exclusively via point-estimate metrics (RMSE, $R^2$). This discards precisely the…

Artificial Intelligence · Computer Science 2026-05-05 Jonas Landsgesell , Pascal Knoll , Tizian Wenzel

Nuclear Magnetic Resonance (NMR) spectroscopy is the cornerstone of small-molecule structure elucidation. While deep learning has demonstrated significant potential in automating structure elucidation and spectral simulation, current…

Computational Engineering, Finance, and Science · Computer Science 2026-01-23 Zheng Fang , Chen Yang , Hai-tao Yu , Haoming Luo , Haitao He , Jiaqing Xie , Zhuo Yang , Jun Xia

The task of understanding and interpreting the complex information encoded within genomic sequences remains a grand challenge in biological research and clinical applications. In this context, recent advancements in large language model…

Genomics · Quantitative Biology 2024-09-25 Qihang Zhao , Chi Zhang , Weixiong Zhang

Video generation models have rapidly progressed, positioning themselves as video world models capable of supporting decision-making applications like robotics and autonomous driving. However, current benchmarks fail to rigorously evaluate…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Dacheng Li , Yunhao Fang , Yukang Chen , Shuo Yang , Shiyi Cao , Justin Wong , Michael Luo , Xiaolong Wang , Hongxu Yin , Joseph E. Gonzalez , Ion Stoica , Song Han , Yao Lu

Visual narrative generation transforms textual narratives into sequences of images illustrating the content of the text. However, generating visual narratives that are faithful to the input text and self-consistent across generated images…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Silin Gao , Sheryl Mathew , Li Mi , Sepideh Mamooler , Mengjie Zhao , Hiromi Wakaki , Yuki Mitsufuji , Syrielle Montariol , Antoine Bosselut

To improve crop genetics, high-throughput, effective and comprehensive phenotyping is a critical prerequisite. While such tasks were traditionally performed manually, recent advances in multimodal foundation models, especially in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Yu Wu , Guangzeng Han , Ibra Niang Niang , Francia Ravelombola , Maiara Oliveira , Jason Davis , Dong Chen , Feng Lin , Xiaolei Huang

Background and objective: Cell-level pathological image analysis requires working with extremely small image patches (40x40 pixels), far below standard ImageNet resolutions. It remains unclear whether modern deep learning architectures and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Hiroki Kagiyama , Toru Nagasaka , Yukari Adachi , Takaaki Tachibana , Ryota Ito , Mitsugu Fujita , Kimihiro Yamashita , Yoshihiro Kakeji

Non-coding RNA structure and function are essential to understanding various biological processes, such as cell signaling, gene expression, and post-transcriptional regulations. These are all among the core problems in the RNA field. With…

Quantitative Methods · Quantitative Biology 2022-08-09 Jiayang Chen , Zhihang Hu , Siqi Sun , Qingxiong Tan , Yixuan Wang , Qinze Yu , Licheng Zong , Liang Hong , Jin Xiao , Tao Shen , Irwin King , Yu Li

The effective application of foundation models to translational research in immune-mediated diseases requires multimodal patient-level representations that can capture complex phenotypes emerging from multicellular interactions. Yet most…

Vision-language models (VLMs) have made significant progress in recent visual-question-answering (VQA) benchmarks that evaluate complex visio-linguistic reasoning. However, are these models truly effective? In this work, we show that VLMs…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Baiqi Li , Zhiqiu Lin , Wenxuan Peng , Jean de Dieu Nyandwi , Daniel Jiang , Zixian Ma , Simran Khanuja , Ranjay Krishna , Graham Neubig , Deva Ramanan

Large Language Models (LLMs) are increasingly being explored for clinical question answering and decision support, yet safe deployment critically requires reliable handling of patient measurements in heterogeneous clinical notes. Existing…

Computation and Language · Computer Science 2026-04-16 Minh-Vuong Nguyen , Fatemeh Shiri , Zhuang Li , Karin Verspoor

Large Language Models (LLMs) and LLM-based agents show great promise in accelerating scientific research. Existing benchmarks for measuring this potential and guiding future development continue to evolve from pure recall and rote knowledge…

Understanding multi-image, multi-turn scenarios is a critical yet underexplored capability for Large Vision-Language Models (LVLMs). Existing benchmarks predominantly focus on static or horizontal comparisons -- e.g., spotting visual…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Wenbo Lyu , Yingjun Du , Jinglin Zhao , Xianton Zhen , Ling Shao

Modern software development demands code that is maintainable, testable, and scalable by organizing the implementation into modular components with iterative reuse of existing codes. We formalize this iterative, multi-turn paradigm as…

Software Engineering · Computer Science 2026-04-16 Sizhe Wang , Zhengren Wang , Dongsheng Ma , Yongan Yu , Rui Ling , Zhiyu Li , Feiyu Xiong , Wentao Zhang

Virtual cell modeling aims to predict cellular responses to perturbations. Existing virtual cell models rely heavily on large-scale single-cell datasets, learning explicit mappings between gene expression and perturbations. Although recent…

Cell Behavior · Quantitative Biology 2026-03-02 Zhijian Wei , Runze Ma , Zichen Wang , Zhongmin Li , Shuotong Song , Shuangjia Zheng

Existing online benchmarks for mobile GUI agents remain largely app-centric and task-homogeneous, failing to reflect the diversity and instability of real-world mobile usage. To this end, we introduce VenusBench-Mobile, a challenging online…

Human-Computer Interaction · Computer Science 2026-04-09 Yichen Gong , Zhuohan Cai , Sunhao Dai , Yuqi Zhou , Zhangxuan Gu , Changhua Meng , Shuheng Shen

Systematic identification of protein function is a key problem in current biology. Most traditional methods fail to identify functionally equivalent proteins if they lack similar sequences, structural data or extensive manual annotations.…

Genomics · Quantitative Biology 2016-03-08 Dan Ofer