English
Related papers

Related papers: GraphDiffMed: Knowledge-Constrained Differential A…

200 papers

Accurate drug response prediction (DRP) is a crucial yet challenging task in precision medicine. This paper presents a novel Attention-Guided Multi-omics Integration (AGMI) approach for DRP, which first constructs a Multi-edge Graph (MeG)…

Genomics · Quantitative Biology 2022-01-20 Ruiwei Feng , Yufeng Xie , Minshan Lai , Danny Z. Chen , Ji Cao , Jian Wu

Medication recommendation is a crucial task in healthcare, especially for patients with complex medical conditions. However, existing methods often struggle to effectively balance the reuse of historical medications with the introduction of…

Artificial Intelligence · Computer Science 2025-07-08 Feiyue Wu , Tianxing Wu , Shenqi Jing

Graph generation is a fundamental problem in graph learning with broad applications across Web-scale systems, knowledge graphs, and scientific domains such as drug and material discovery. Recent approaches leverage diffusion models for…

Machine Learning · Computer Science 2026-03-18 Jiachi Zhao , Zehong Wang , Yamei Liao , Chuxu Zhang , Yanfang Ye

Aiming at the limitations of traditional medical decision system in processing large-scale heterogeneous medical data and realizing highly personalized recommendation, this paper introduces a personalized medical decision algorithm…

Machine Learning · Computer Science 2024-05-29 Yafeng Yan , Shuyao He , Zhou Yu , Jiajie Yuan , Ziang Liu , Yan Chen

Sequential Recommendation (SR) characterizes evolving patterns of user behaviors by modeling how users transit among items. However, the short interaction sequences limit the performance of existing SR. To solve this problem, we focus on…

Information Retrieval · Computer Science 2022-09-22 Xiaolin Zheng , Jiajie Su , Weiming Liu , Chaochao Chen

Biases in automated clinical decision-making using Electronic Healthcare Records (EHR) impose significant disparities in patient care and treatment outcomes. Conventional approaches have primarily focused on bias mitigation strategies…

Artificial Intelligence · Computer Science 2024-12-03 Resmi Ramachandranpillai , Kishore Sampath , Ayaazuddin Mohammad , Malihe Alikhani

Recommender systems are widely used in various real-world applications, but they often encounter the persistent challenge of the user cold-start problem. Cross-domain recommendation (CDR), which leverages user interactions from one domain…

Information Retrieval · Computer Science 2025-02-13 Hourun Li , Yifan Wang , Zhiping Xiao , Jia Yang , Changling Zhou , Ming Zhang , Wei Ju

Electronic health record (EHR) systems present clinicians with vast repositories of clinical information, creating a significant cognitive burden where critical details are easily overlooked. While Large Language Models (LLMs) offer…

Computation and Language · Computer Science 2026-03-17 Samuel Thio , Matthew Lewis , Spiros Denaxas , Richard JB Dobson

In the contemporary age characterized by information abundance, rapid advancements in artificial intelligence have rendered recommendation systems indispensable. Conventional recommendation methodologies based on collaborative filtering or…

Information Retrieval · Computer Science 2025-09-04 Yu Fang

Adverse Drug Reaction (ADR) is a significant public health concern world-wide. Numerous graph-based methods have been applied to biomedical graphs for predicting ADRs in pre-marketing phases. ADR detection in post-market surveillance is no…

Machine Learning · Computer Science 2020-04-02 Heeyoung Kwak , Minwoo Lee , Seunghyun Yoon , Jooyoung Chang , Sangmin Park , Kyomin Jung

Clinical tasks such as diagnosis and treatment require strong decision-making abilities, highlighting the importance of rigorous evaluation benchmarks to assess the reliability of large language models (LLMs). In this work, we introduce a…

Computation and Language · Computer Science 2025-07-04 Running Yang , Wenlong Deng , Minghui Chen , Yuyin Zhou , Xiaoxiao Li

While electronic health records (EHRs) are widely used across various applications in healthcare, most applications use the EHRs in their raw (tabular) format. Relying on raw or simple data pre-processing can greatly limit the performance…

Machine Learning · Computer Science 2024-03-28 Fahmida Liza Piya , Mehak Gupta , Rahmatollah Beheshti

Large-scale Electronic Health Record (EHR) databases have become indispensable in supporting clinical decision-making through data-driven treatment recommendations. However, existing medication recommender methods often struggle with a user…

Machine Learning · Computer Science 2026-02-02 Arya Hadizadeh Moghaddam , Mohsen Nayebi Kerdabadi , Dongjie Wang , Mei Liu , Zijun Yao

Diffusion models (DMs) have emerged as promising approaches for sequential recommendation due to their strong ability to model data distributions and generate high-quality items. Existing work typically adds noise to the next item and…

Information Retrieval · Computer Science 2025-02-12 Wenyu Mao , Shuchang Liu , Haoyang Liu , Haozhe Liu , Xiang Li , Lantao Hu

Heterogeneous information network has been widely used to alleviate sparsity and cold start problems in recommender systems since it can model rich context information in user-item interactions. Graph neural network is able to encode this…

Information Retrieval · Computer Science 2021-06-22 Yifan Wang , Suyao Tang , Yuntong Lei , Weiping Song , Sheng Wang , Ming Zhang

Routine clinical visits of a patient produce not only image data, but also non-image data containing clinical information regarding the patient, i.e., medical data is multi-modal in nature. Such heterogeneous modalities offer different and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Sein Kim , Namkyeong Lee , Junseok Lee , Dongmin Hyun , Chanyoung Park

With the rapid emergence of multi-behavior learning in recommender systems, leveraging auxiliary user behaviors has proven effective for mitigating target-behavior data sparsity. Yet auxiliary behavior graphs frequently contain noisy or…

Information Retrieval · Computer Science 2026-05-26 Likang Wu , Zihao Chen , Jianxin Zhang , Sangqi Zhu , Yuanyuan Ge , Haipeng Yang , Lei Zhang

Instance-aware embeddings predicted by deep neural networks have revolutionized biomedical instance segmentation, but its resource requirements are substantial. Knowledge distillation offers a solution by transferring distilled knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-01-15 Xiaoyu Liu , Yueyi Zhang , Zhiwei Xiong , Wei Huang , Bo Hu , Xiaoyan Sun , Feng Wu

In the treatment of complex diseases, treatment regimens using a single drug often yield limited efficacy and can lead to drug resistance. In contrast, combination drug therapies can significantly improve therapeutic outcomes through…

Machine Learning · Computer Science 2026-04-24 Jiyan Song , Wenyang Wang , Chengcheng Yan , Zhiquan Han , Feifei Zhao

Pre-training Graph Foundation Models (GFMs) on text-attributed graphs (TAGs) is central to web-scale applications such as search, recommendation, and knowledge discovery. However, existing CLIP-style graph-text aligners face two key…

Machine Learning · Computer Science 2025-10-23 Yuhang Liu , Minglai Shao , Zengyi Wo , Yunlong Chu , Bing Hao , Shengzhong Liu , Ruijie Wang , Jianxin Li