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Medication recommendation is a crucial task for assisting physicians in making timely decisions from longitudinal patient medical records. However, real-world EHR data present significant challenges due to the presence of rarely observed…

Artificial Intelligence · Computer Science 2025-08-15 Yan Ting Chok , Soyon Park , Seungheun Baek , Hajung Kim , Junhyun Lee , Jaewoo Kang

Medication recommendation is a vital task for improving patient care and reducing adverse events. However, existing methods often fail to capture the complex and dynamic relationships among patient medical records, drug efficacy and safety,…

Artificial Intelligence · Computer Science 2023-12-15 Minh-Van Nguyen , Duy-Thinh Nguyen , Quoc-Huy Trinh , Bac-Hoai Le

Knowledge Graphs have been one of the fundamental methods for integrating heterogeneous data sources. Integrating heterogeneous data sources is crucial, especially in the biomedical domain, where central data-driven tasks such as drug…

Machine Learning · Computer Science 2020-12-22 Islam Akef Ebeid , Majdi Hassan , Tingyi Wanyan , Jack Roper , Abhik Seal , Ying Ding

Recently, real-world recommendation systems need to deal with millions of candidates. It is extremely challenging to conduct sophisticated end-to-end algorithms on the entire corpus due to the tremendous computation costs. Therefore,…

Information Retrieval · Computer Science 2021-10-15 Ruobing Xie , Qi Liu , Shukai Liu , Ziwei Zhang , Peng Cui , Bo Zhang , Leyu Lin

Medication recommendation aims to integrate patients' long-term health records to provide accurate and safe medication combinations for specific health states. Existing methods often fail to deeply explore the true causal relationships…

Information Retrieval · Computer Science 2024-10-31 Shunpan Liang , Xiang Li , Shi Mu , Chen Li , Yu Lei , Yulei Hou , Tengfei Ma

Due to the highly sensitive nature of certain data in cross-border sharing, collaborative cross-border recommendations and data sharing are often subject to stringent privacy protection regulations, resulting in insufficient data for model…

Machine Learning · Computer Science 2025-05-27 Zhizhong Tan , Jiexin Zheng , Xingxing Yang , Chi Zhang , Weiping Deng , Wenyong Wang

Multimedia recommendations aim to use rich multimedia content to enhance historical user-item interaction information, which can not only indicate the content relatedness among items but also reveal finer-grained preferences of users. In…

Multimedia · Computer Science 2025-07-23 Xian Mo , Fei Liu , Rui Tang , Jintao , Gao , Hao Liu

Recent advances in Graph Neural Networks (GNNs) have revolutionized graph-structured data modeling, yet traditional GNNs struggle with complex heterogeneous structures prevalent in real-world scenarios. Despite progress in handling…

Machine Learning · Computer Science 2025-01-07 Zongwei Li , Lianghao Xia , Hua Hua , Shijie Zhang , Shuangyang Wang , Chao Huang

We present an end-to-end, interpretable, deep-learning architecture to learn a graph kernel that predicts the outcome of chronic disease drug prescription. This is achieved through a deep metric learning collaborative with a Support Vector…

Machine Learning · Computer Science 2020-08-06 Hao-Ren Yao , Der-Chen Chang , Ophir Frieder , Wendy Huang , I-Chia Liang , Chi-Feng Hung

Examining Drug-Drug Interactions (DDIs) is a pivotal element in the process of drug development. DDIs occur when one drug's properties are affected by the inclusion of other drugs. Detecting favorable DDIs has the potential to pave the way…

Machine Learning · Computer Science 2026-03-20 Azmine Toushik Wasi , Taki Hasan Rafi , Raima Islam , Serbetar Karlo , Dong-Kyu Chae

In real-world recommendation scenarios, users typically engage with platforms through multiple types of behavioral interactions. Multi-behavior recommendation algorithms aim to leverage various auxiliary user behaviors to enhance prediction…

Information Retrieval · Computer Science 2025-07-22 Hengyu Zhang , Chunxu Shen , Xiangguo Sun , Jie Tan , Yanchao Tan , Yu Rong , Hong Cheng , Lingling Yi

Drug-drug interactions (DDIs) represent a critical challenge in pharmacology, often leading to adverse drug reactions with significant implications for patient safety and healthcare outcomes. While graph-based methods have achieved strong…

Machine Learning · Computer Science 2025-07-15 Mengjie Chen , Ming Zhang , Cunquan Qu

Multimodal recommendation systems integrate diverse multimodal information into the feature representations of both items and users, thereby enabling a more comprehensive modeling of user preferences. However, existing methods are hindered…

Multimedia · Computer Science 2025-01-03 Qiya Song , Jiajun Hu , Lin Xiao , Bin Sun , Xieping Gao , Shutao Li

Recently, diffusion-based recommendation methods have achieved impressive results. However, existing approaches predominantly treat each user's historical interactions as independent training samples, overlooking the potential of…

Social and Information Networks · Computer Science 2025-04-08 Xuan Zhang , Xiang Deng , Hongxing Yuan , Chunyu Wei , Yushun Fan

Accurate prediction of drug-drug interactions (DDI) is crucial for medication safety and effective drug development. However, existing methods often struggle to capture structural information across different scales, from local functional…

Machine Learning · Computer Science 2026-03-27 Zimo Yan , Jie Zhang , Zheng Xie , Yiping Song , Hao Li

Human Activity Recognition (HAR) using multimodal sensor data remains challenging due to noisy or incomplete measurements, scarcity of labeled examples, and privacy concerns. Traditional centralized deep learning approaches are often…

Machine Learning · Computer Science 2025-09-09 Labani Halder , Tanmay Sen , Sarbani Palit

Significant progress has been made using fMRI to characterize the brain changes that occur in ASD, a complex neuro-developmental disorder. However, due to the high dimensionality and low signal-to-noise ratio of fMRI, embedding informative…

Image and Video Processing · Electrical Eng. & Systems 2019-08-15 Xiaoxiao Li , Nicha C. Dvornek , Juntang Zhuang , Pamela Ventola , James Duncan

Medical image classification plays a crucial role in computer-aided clinical diagnosis. While deep learning techniques have significantly enhanced efficiency and reduced costs, the privacy-sensitive nature of medical imaging data…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Sufen Ren , Yule Hu , Shengchao Chen , Guanjun Wang

Predicting drug-gene associations is crucial for drug development and disease treatment. While graph neural networks (GNN) have shown effectiveness in this task, they face challenges with data sparsity and efficient contrastive learning…

Machine Learning · Computer Science 2025-02-14 Jiayang Wu , Wensheng Gan , Philip S. Yu

Motivation: Predicting Drug-Target Interaction (DTI) is a well-studied topic in bioinformatics due to its relevance in the fields of proteomics and pharmaceutical research. Although many machine learning methods have been successfully…

Quantitative Methods · Quantitative Biology 2021-07-14 Haiyang Wang , Guangyu Zhou , Siqi Liu , Jyun-Yu Jiang , Wei Wang