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We developed Distilled Graph Attention Policy Network (DGAPN), a reinforcement learning model to generate novel graph-structured chemical representations that optimize user-defined objectives by efficiently navigating a physically…

Learning electronic health records (EHRs) has received emerging attention because of its capability to facilitate accurate medical diagnosis. Since the EHRs contain enriched information specifying complex interactions between entities,…

Machine Learning · Computer Science 2024-08-15 Tsai Hor Chan , Guosheng Yin , Kyongtae Bae , Lequan Yu

Federated training methods have gained popularity for graph learning with applications including friendship graphs of social media sites and customer-merchant interaction graphs of huge online marketplaces. However, privacy regulations…

Machine Learning · Computer Science 2024-12-23 Siddharth Ambekar , Yuhang Yao , Ryan Li , Carlee Joe-Wong

Electronic medical records contain multi-format electronic medical data that consist of an abundance of medical knowledge. Facing with patient's symptoms, experienced caregivers make right medical decisions based on their professional…

Databases · Computer Science 2017-07-25 Meng Wang , Jiaheng Zhang , Jun Liu , Wei Hu , Sen Wang , Xue Li , Wenqiang Liu

Multimodal recommender systems (MRSs) are critical for various online platforms, offering users more accurate personalized recommendations by incorporating multimodal information of items. Structure-based MRSs have achieved state-of-the-art…

Information Retrieval · Computer Science 2025-12-24 Ziyuan Guo , Jie Guo , Zhenghao Chen , Bin Song , Fei Richard Yu

Adverse Drug Reactions (ADRs) are characterized within randomized clinical trials and postmarketing pharmacovigilance, but their molecular mechanism remains unknown in most cases. Aside from clinical trials, many elements of knowledge about…

Federated Learning (FL) offers a promising approach for training clinical AI models without centralizing sensitive patient data. However, its real-world adoption is hindered by challenges related to privacy, resource constraints, and…

Diffusion Probabilistic Models have recently shown remarkable performance in generative image modeling, attracting significant attention in the computer vision community. However, while a substantial amount of diffusion-based research has…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Yijun Yang , Huazhu Fu , Angelica I. Aviles-Rivero , Carola-Bibiane Schönlieb , Lei Zhu

Unsupervised representation learning for dynamic graphs has attracted a lot of research attention in recent years. Compared with static graph, the dynamic graph is a comprehensive embodiment of both the intrinsic stable characteristics of…

Social and Information Networks · Computer Science 2023-08-17 Kaike Zhang , Qi Cao , Gaolin Fang , Bingbing Xu , Hongjian Zou , Huawei Shen , Xueqi Cheng

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

High failure rates in cardiac drug development necessitate virtual clinical trials via electrocardiogram (ECG) generation to reduce risks and costs. However, existing ECG generation models struggle to balance morphological realism with…

Machine Learning · Computer Science 2026-03-31 Qian Shao , Bang Du , Zepeng Li , Qiyuan Chen , Jiahe Chen , Hongxia Xu , Jimeng Sun , Jian Wu , Jintai Chen

Accurate prediction of drug response in precision medicine requires models that capture how specific chemical substructures interact with cellular pathway states. However, most existing deep learning approaches treat chemical and…

Machine Learning · Computer Science 2026-04-14 Yewon Han , Sunghyun Kim , Eunyi Jeong , Sungkyung Lee , Seokwoo Yun , Sangsoo Lim

Human activity recognition (HAR) through wearable devices has received much interest due to its numerous applications in fitness tracking, wellness screening, and supported living. As a result, we have seen a great deal of work in this…

Machine Learning · Computer Science 2022-06-13 Nafees Ahmad , Savio Ho-Chit Chow , Ho-fung Leung

The increased amount of multi-modal medical data has opened the opportunities to simultaneously process various modalities such as imaging and non-imaging data to gain a comprehensive insight into the disease prediction domain. Recent…

Machine Learning · Computer Science 2021-11-24 Mahsa Ghorbani , Mojtaba Bahrami , Anees Kazi , Mahdieh SoleymaniBaghshah , Hamid R. Rabiee , Nassir Navab

Recent deep learning approaches have shown promise in learning such individual brain parcellations from functional magnetic resonance imaging (fMRI). However, most existing methods assume consistent data distributions across domains and…

Artificial Intelligence · Computer Science 2025-07-30 Jianfei Zhu , Haiqi Zhu , Shaohui Liu , Feng Jiang , Baichun Wei , Chunzhi Yi

Building models for health prediction based on Electronic Health Records (EHR) has become an active research area. EHR patient journey data consists of patient time-ordered clinical events/visits from patients. Most existing studies focus…

Machine Learning · Computer Science 2022-07-18 Yuxi Liu , Zhenhao Zhang , Antonio Jimeno Yepes , Flora D. Salim

Recommender systems are essential components of modern online platforms which presents personalized content in various domain. The traditional collaborative filtering methods depends on static user-item interaction graphs and a limited…

Information Retrieval · Computer Science 2026-05-08 Aadarsh Senapati , Neha Kujur , Vivek Yelleti

Pharmaco-epidemiology (PE) is the study of uses and effects of drugs in well defined populations. As medico-administrative databases cover a large part of the population, they have become very interesting to carry PE studies. Such databases…

Artificial Intelligence · Computer Science 2017-09-12 Yann Dauxais , Thomas Guyet , David Gross-Amblard , André Happe

With the development of deep convolutional neural networks, medical image segmentation has achieved a series of breakthroughs in recent years. However, the high-performance convolutional neural networks always mean numerous parameters and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-30 Wenxuan Zou , Muyi Sun

Addressing the challenges related to data sparsity, cold-start problems, and diversity in recommendation systems is both crucial and demanding. Many current solutions leverage knowledge graphs to tackle these issues by combining both…

Information Retrieval · Computer Science 2024-03-28 Yejin Kim , Scott Rome , Kevin Foley , Mayur Nankani , Rimon Melamed , Javier Morales , Abhay Yadav , Maria Peifer , Sardar Hamidian , H. Howie Huang
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