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This review proposes an integrative framework grounded on interoception and embodied AI-termed the interoceptive machine framework-that translates biologically inspired principles of internal-state regulation into computational…
Living systems, from single cells to higher vertebrates, receive a continuous stream of non-stationary inputs that they sense, e.g., via cell surface receptors or sensory organs. Integrating these time-varying, multi-sensory, and often…
Artificial Intelligence (AI) algorithms are increasingly providing decision making and operational support across multiple domains. AI includes a wide library of algorithms for different problems. One important notion for the adoption of AI…
As AI systems become increasingly capable, safety strategies must be evaluated not only by how much they reduce present risk, but by whether they could sustain safety once external control can no longer reliably constrain system behavior.…
In this thesis, we develop algorithms with theoretical guarantees for ensuring reliability and accountability of Machine Learning (ML) systems. As ML systems evolve from predictive models to generative models and autonomous agents, the…
As AI rapidly advances, the security risks posed by AI are becoming increasingly severe, especially in critical scenarios, including those posing existential risks. If AI becomes uncontrollable, manipulated, or actively evades safety…
There is a growing trend in molecular and synthetic biology of using mechanistic (non machine learning) models to design biomolecular networks. Once designed, these networks need to be validated by experimental results to ensure the…
Agentic AI seeks to endow systems with sustained autonomy, reasoning, and interaction capabilities. To realize this vision, its assumptions about agency must be complemented by explicit models of cognition, cooperation, and governance. This…
Scientific discovery relies on scientists generating novel hypotheses that undergo rigorous experimental validation. To augment this process, we introduce an AI co-scientist, a multi-agent system built on Gemini 2.0. The AI co-scientist is…
The problem of reliability of the dynamics in biological regulatory networks is studied in the framework of a generalized Boolean network model with continuous timing and noise. Using well-known artificial genetic networks such as the…
Autonomous agents operating in sequential decision-making tasks under uncertainty can benefit from external action suggestions, which provide valuable guidance but inherently vary in reliability. Existing methods for incorporating such…
Artificial Intelligence (AI) benchmarks play a central role in measuring progress in model development and guiding deployment decisions. However, many benchmarks quickly become saturated, meaning that they can no longer differentiate…
This paper presents Bayesian techniques for conservative claims about software reliability, particularly when evidence suggests the software's executions are not statistically independent. We formalise informal notions of "doubting" that…
Retrieval-augmented generation (RAG) systems have become widely used for enhancing large language model capabilities, but they introduce significant security vulnerabilities through prompt injection attacks. We present a comprehensive…
Traditional models of market efficiency assume that equity prices incorporate information based on content alone, often neglecting the structural influence of reporting timing and cadence. This study introduces the Autonomous Disclosure…
Genetic regulation is a key component in development, but a clear understanding of the structure and dynamics of genetic networks is not yet at hand. In this work we investigate these properties within an artificial genome model originally…
The rapid advancement of artificial intelligence (AI) systems suggests that artificial general intelligence (AGI) systems may soon arrive. Many researchers are concerned that AIs and AGIs will harm humans via intentional misuse (AI-misuse)…
Quality assurance for large-scale cyber-physical systems relies on sophisticated test activities using complex test environments investigated with the help of numerous types of simulators. As these systems grow, extensive resources are…
AI-driven recruitment systems, while promising efficiency and objectivity, often perpetuate systemic inequalities by encoding cultural and social capital disparities into algorithmic decision making. This article develops and defends a…
Biological networks of interacting agents exhibit similar topological properties for a wide range of scales, from cellular to ecological levels, suggesting the existence of a common evolutionary origin. A general evolutionary mechanism…