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The rapid adoption of generative artificial intelligence (GenAI) in the biosciences is transforming biotechnology, medicine, and synthetic biology. Yet this advancement is intrinsically linked to new vulnerabilities, as GenAI lowers the…
In this paper, we show how Behavior Trees that have performance guarantees, in terms of safety and goal convergence, can be extended with components that were designed using machine learning, without destroying those performance guarantees.…
Long-term autonomy requires autonomous systems to adapt as their capabilities no longer perform as expected. To achieve this, a system must first be capable of detecting such changes. In this position paper, we describe a system…
Recent advancements in generative machine learning have enabled rapid progress in biological design tools (BDTs) such as protein structure and sequence prediction models. The unprecedented predictive accuracy and novel design capabilities…
Autonomous AI agents lack traceable accountability mechanisms, creating a fundamental dilemma where systems must either operate as ``downgraded tools'' or risk real-world abuse. This vulnerability stems from the limitations of traditional…
Across academia, industry, and government, there is an increasing awareness that the measurement tasks involved in evaluating generative AI (GenAI) systems are especially difficult. We argue that these measurement tasks are highly…
In this study, we explored the progression trajectories of artificial intelligence (AI) systems through the lens of complexity theory. We challenged the conventional linear and exponential projections of AI advancement toward Artificial…
This position paper argues that AI-assisted software engineering requires explicit mechanisms for tracking the epistemic status and temporal validity of architectural decisions. LLM coding assistants generate decisions faster than teams can…
We study the selection of agents based on mutual nominations, a theoretical problem with many applications from committee selection to AI alignment. As agents both select and are selected, they may be incentivized to misrepresent their true…
Typically, AI researchers and roboticists try to realize intelligent behavior in machines by tuning parameters of a predefined structure (body plan and/or neural network architecture) using evolutionary or learning algorithms. Another but…
We introduce bio-inspired artificial neural networks consisting of neurons that are additionally characterized by spatial positions. To simulate properties of biological systems we add the costs penalizing long connections and the proximity…
Various AI models are increasingly being considered as part of clinical decision-support tools. However, the trustworthiness of such models is rarely considered. Clinicians are more likely to use a model if they can understand and trust its…
Artificial Intelligence (AI) agents have rapidly evolved from specialized, rule-based programs to versatile, learning-driven autonomous systems capable of perception, reasoning, and action in complex environments. The explosion of data,…
The structure and dynamics of a typical biological system are complex due to strong and inhomogeneous interactions between its constituents. The investigation of such systems with classical mathematical tools, such as differential equations…
To counter fragmented, high-risk adoption of commercial AI tools, we built and ran an institutional AI platform in a six-month, 300-user pilot, showing that a university of applied sciences can offer advanced AI with fair access,…
International agreements about AI development may be required to reduce catastrophic risks from advanced AI systems. However, agreements about such a high-stakes technology must be backed by verification mechanisms--processes or tools that…
In a previous paper the authors argued the case for incorporating ideas from innate immunity into artificial immune systems (AISs) and presented an outline for a conceptual framework for such systems. A number of key general properties…
Large language models have demonstrated remarkable performance in a wide range of medical benchmarks. Yet underneath the seemingly promising results lie salient growth areas, especially in cutting-edge frontiers such as multimodal…
With the steady rise of the use of AI in bio-technical applications and the widespread adoption of genomics sequencing, an increasing amount of AI-based algorithms and tools is entering the research and production stage affecting critical…
Catastrophic forgetting has been the leading issue in the domain of lifelong learning in artificial systems. Current artificial systems are reasonably good at learning domains they have seen before; however, as soon as they encounter…