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The age estimation task aims to use facial features to predict the age of people and is widely used in public security, marketing, identification, and other fields. However, the features are mainly concentrated in facial keypoints, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Yiping Zhang , Yuntao Shou , Tao Meng , Wei Ai , Keqin Li

Face aging is to render a given face to predict its future appearance, which plays an important role in the information forensics and security field as the appearance of the face typically varies with age. Although impressive results have…

Computer Vision and Pattern Recognition · Computer Science 2021-01-27 Zhizhong Huang , Shouzhen Chen , Junping Zhang , Hongming Shan

Background: Recent assays for individual-specific genome-wide DNA methylation profiles have enabled epigenome-wide association studies to identify specific CpG sites associated with a phenotype. Computational prediction of CpG site-specific…

Genomics · Quantitative Biology 2015-11-12 Weiwei Zhang , Tim D Spector , Panos Deloukas , Jordana T Bell , Barbara E Engelhardt

My analysis uses methods developed for data mining microarray experiments, adapted for ageing research. Methods bridge knowledge of statistical mechanics with data mining methods developed in statistical mathematics. Analyses can reveal how…

Quantitative Methods · Quantitative Biology 2012-12-11 Diana David-Rus

Gene expression (GE) data capture valuable condition-specific information ("condition" can mean a biological process, disease stage, age, patient, etc.) However, GE analyses ignore physical interactions between gene products, i.e.,…

Molecular Networks · Quantitative Biology 2020-04-16 Khalique Newaz , Tijana Milenkovic

Combining different modalities of data from human tissues has been critical in advancing biomedical research and personalised medical care. In this study, we leverage a graph embedding model (i.e VGAE) to perform link prediction on…

Genomics · Quantitative Biology 2021-07-27 Amine Amor , Pietro Lio' , Vikash Singh , Ramon Viñas Torné , Helena Andres Terre

Medical time series has been playing a vital role in real-world healthcare systems as valuable information in monitoring health conditions of patients. Accurate classification for medical time series, e.g., Electrocardiography (ECG)…

Machine Learning · Computer Science 2025-02-10 Wei Fan , Jingru Fei , Dingyu Guo , Kun Yi , Xiaozhuang Song , Haolong Xiang , Hangting Ye , Min Li

Predictive tasks on relational databases are critical in real-world applications spanning e-commerce, healthcare, and social media. To address these tasks effectively, Relational Deep Learning (RDL) encodes relational data as graphs,…

Machine Learning · Computer Science 2025-06-10 Tianlang Chen , Charilaos Kanatsoulis , Jure Leskovec

Cell-free DNA (cfDNA) analysis is a powerful, minimally invasive tool for monitoring disease progression, treatment response, and early detection. A major challenge, however, is accurately determining the tissue of origin, especially in…

Genomics · Quantitative Biology 2025-06-03 Keng-Jung Lee , Dharanya Sampath , Konstantinos Mavrommatis

Methylation of CpG dinucleotides is a prevalent epigenetic modification that is required for proper development in vertebrates, and changes in CpG methylation are essential to cellular differentiation. Genome-wide DNA methylation assays…

Genomics · Quantitative Biology 2014-08-28 John A. Capra , Dennis Kostka

The difference between the chronological and biological brain age of a subject can be an important biomarker for neurodegenerative diseases, thus brain age estimation can be crucial in clinical settings. One way to incorporate multimodal…

Subgraph representation learning based on Graph Neural Network (GNN) has exhibited broad applications in scientific advancements, such as predictions of molecular structure-property relationships and collective cellular function. In…

Machine Learning · Computer Science 2022-10-17 Yili Shen , Xiao Liu , Cheng-Wei Ju , Jiaxu Yan , Jun Yi , Zhou Lin , Hui Guan

Epigenetics is the study of how people's behavior and environments influence the way their genes are expressed, even though their DNA sequence is itself unchanged. By aggregating age-related epigenetic markers, epigenetic 'clocks' have…

General Economics · Economics 2025-09-19 Giorgia Menta , Pietro Biroli , Divya Mehta , Conchita D'Ambrosio , Deborah Cobb-Clark

Synthetic lethality (SL) prediction is used to identify if the co-mutation of two genes results in cell death. The prevalent strategy is to abstract SL prediction as an edge classification task on gene nodes within SL data and achieve it…

Machine Learning · Computer Science 2023-10-18 Xusheng Zhao , Hao Liu , Qiong Dai , Hao Peng , Xu Bai , Huailiang Peng

Radiologists and doctors make use of X-ray images of the non-dominant hands of children and infants to assess the possibility of genetic conditions and growth abnormalities. This is done by assessing the difference between the actual extent…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Nandavardhan R. , Somanathan R. , Vikram Suresh , Savaridassan P

Face aging is the task aiming to translate the faces in input images to designated ages. To simplify the problem, previous methods have limited themselves only able to produce discrete age groups, each of which consists of ten years.…

Computer Vision and Pattern Recognition · Computer Science 2021-03-01 Seogkyu Jeon , Pilhyeon Lee , Kibeom Hong , Hyeran Byun

Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further…

Convolutional Neural Networks play a key role in bone age assessment for investigating endocrinology, genetic, and growth disorders under various modalities and body regions. However, no researcher has tackled bone age…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Shinji Nakazawa , Changhee Han , Joe Hasei , Ryuichi Nakahara , Toshifumi Ozaki

Face aging, which renders aging faces for an input face, has attracted extensive attention in the multimedia research. Recently, several conditional Generative Adversarial Nets (GANs) based methods have achieved great success. They can…

Computer Vision and Pattern Recognition · Computer Science 2018-02-02 Si Liu , Yao Sun , Defa Zhu , Renda Bao , Wei Wang , Xiangbo Shu , Shuicheng Yan

Relational Deep Learning (RDL) is a promising approach for building state-of-the-art predictive models on multi-table relational data by representing it as a heterogeneous temporal graph. However, commonly used Graph Neural Network models…