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In deep tissue photoacoustic imaging the spatial resolution is inherently limited by the acoustic wavelength. We present an approach for surpassing the acoustic diffraction limit by exploiting temporal fluctuations in the sample absorption…

Optics · Physics 2017-05-31 Thomas Chaigne , Bastien Arnal , Sergey Vilov , Emmanuel Bossy , Ori Katz

Our work aims at using quantitative imaging tools to complement the limitation of noise encountered by high resolution fluorescence microscopy methods. Several cycles of fluorophore activation, imaging and deactivation produce a sequence of…

Quantitative Methods · Quantitative Biology 2012-02-03 Juliane Liepe , Federico Felizzi , Agata Pernus , Maria Hanulova

Superresolution refers to the estimation of parameters of an image with an accuracy beyond standard classical techniques such as direct detection. In seminal work by Lu et al., a measurement to estimate the separation distance of two point…

Quantum Physics · Physics 2022-06-30 Hari Krovi

Structured illumination microscopy (SIM) uses a set of images captured with different illumination patterns to computationally reconstruct resolution beyond the diffraction limit. Here, we propose an alternative approach using a single…

Optics · Physics 2025-06-17 Ruiming Cao , Guanghan Meng , Laura Waller

In this paper we aim to tackle the problem of reconstructing a high-resolution image from a single low-resolution input image, known as single image super-resolution. In the literature, sparse representation has been used to address this…

Computer Vision and Pattern Recognition · Computer Science 2016-03-23 Mohammad Rostami , Zhou Wang

An interferometric fluorescent microscope and a novel theoretic image reconstruction approach were developed and used to obtain super-resolution images of live biological samples and to enable dynamic real time tracking. The tracking…

Foundation models offer a promising route to transferable remote sensing representations, but many current approaches depend on very large pretraining datasets and fixed sensor configurations, limiting their suitability for ecological and…

MINFLUX microscopy allows for localization of fluorophores with nanometer precision using targeted scanning with an illumination profile with a minimum. However, current scanning patterns and the overall procedure are based on heuristics,…

Computational Physics · Physics 2026-04-17 Steffen Schultze , Helmut Grubmüller

Scalable atom-based quantum platforms for simulation, computing, and metrology require fast high-fidelity, low-loss imaging of individual atoms. Standard fluorescence detection methods rely on continuous cooling, limiting the detection…

Super-resolution imaging based on single molecule localization allows accessing nanometric-scale information in biological samples with high precision. However, complete measurements including molecule orientation are still challenging.…

The purpose of this study is to enable in-vivo three-dimensional (3-D) ultrasound localization microscopy (ULM) of posterior ocular microvasculature using a 256-channel system and a 1024-element matrix array, and to overcome limitations of…

Confocal fluorescence microscopy is one of the most accessible and widely used imaging techniques for the study of biological processes at the cellular and subcellular levels. Scanning confocal microscopy allows the capture of high-quality…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Soufiane Belharbi , Mara KM Whitford , Phuong Hoang , Shakeeb Murtaza , Luke McCaffrey , Eric Granger

Image stabilization performed during imaging and/or post-processing poses one of the most significant challenges to photo-response non-uniformity based source camera attribution from videos. When performed digitally, stabilization involves…

Image and Video Processing · Electrical Eng. & Systems 2020-11-25 Enes Altinisik , Husrev Taha Sencar

We present a parameter-decoupled superresolution framework for estimating sub-wavelength separations of passive two-point sources without requiring prior knowledge or control of the source. Our theoretical foundation circumvents the need to…

We introduce a new algorithm designed for use with extended lensed images, specifically giant arcs lensed by galaxy clusters. These highly magnified images contain important information about both the mass distribution of the cluster and…

Cosmology and Nongalactic Astrophysics · Physics 2026-05-25 Lana Eid , Charles Keeton

While super-resolution (SR) methods based on diffusion models exhibit promising results, their practical application is hindered by the substantial number of required inference steps. Recent methods utilize degraded images in the initial…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Yufei Wang , Wenhan Yang , Xinyuan Chen , Yaohui Wang , Lanqing Guo , Lap-Pui Chau , Ziwei Liu , Yu Qiao , Alex C. Kot , Bihan Wen

Imaging across both the full transverse spatial and temporal dimensions of a scene with high precision in all three coordinates is key to applications ranging from LIDAR to fluorescence lifetime imaging. However, compromises that sacrifice,…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 C. Callenberg , A. Lyons , D. den Brok , A. Fatima , A. Turpin , V. Zickus , L. Machesky , J. Whitelaw , D. Faccio , M. B. Hullin

Super-resolution effects in optical and fluorescence biological systems are analyzed and their relations with uncertainty relations are discussed. Super-resolutions obtained in the optical systems, including especially NSOM, SIM and…

Optics · Physics 2015-06-12 Yacob Ben-Aryeh

Super-resolution mapping of the 3D orientation of fluorophores reveals the alignment of biological structures where the fluorophores are tightly attached, and thus plays a vital role in studying the organization and dynamics of…

Optics · Physics 2024-01-23 Xiaowei Liu , Mingwei Tang , Ning Zhou , Chenlei Pang , Zhong Wen , Xu Liu , Qing Yang

In minimally invasive surgery, surgical instrument localization is a crucial task for endoscopic videos, which enables various applications for improving surgical outcomes. However, annotating the instrument localization in endoscopic…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Rongfeng Wei , Jinlin Wu , Xuexue Bai , Ming Feng , Zhen Lei , Hongbin Liu , Zhen Chen
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