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Compartmental models provide simple and efficient tools to analyze the relevant transmission processes during an outbreak, to produce short-term forecasts or transmission scenarios, and to assess the impact of vaccination campaigns.…

Numerical Analysis · Mathematics 2025-02-19 Caterina Millevoi , Damiano Pasetto , Massimiliano Ferronato

Physics-informed neural networks (PINNs) are neural networks that embed the laws of dynamical systems modeled by differential equations into their loss function as constraints. In this work, we present a PINN framework applied to oncology.…

Machine Learning · Computer Science 2025-10-16 Kayode Olumoyin , Katarzyna Rejniak

Brain stroke remains one of the principal causes of death and disability worldwide, yet most tabular-data prediction models still hover below the 95% accuracy threshold, limiting real-world utility. Addressing this gap, the present work…

Quantitative Methods · Quantitative Biology 2026-05-22 Yousuf Islam , Md. Jalal Uddin Chowdhury , Sumon Chandra Das

Accurate estimation of tacrolimus exposure, quantified by the area under the concentration-time curve (AUC), is essential for precision dosing after renal transplantation. Current practice relies on population pharmacokinetic (PopPK) models…

Machine Learning · Statistics 2026-02-04 Benjamin Maurel , Agathe Guilloux , Sarah Zohar , Moreno Ursino , Jean-Baptiste Woillard

Neural Ordinary Differential Equations (NODEs) have proven to be a powerful modeling tool for approximating (interpolation) and forecasting (extrapolation) irregularly sampled time series data. However, their performance degrades…

Machine Learning · Computer Science 2020-04-29 Hammad A. Ayyubi , Yi Yao , Ajay Divakaran

Accurate epidemic forecasting is crucial for effective disease control and prevention. Traditional compartmental models often struggle to estimate temporally and spatially varying epidemiological parameters, while deep learning models…

Machine Learning · Computer Science 2025-04-08 Shuai Han , Lukas Stelz , Thomas R. Sokolowski , Kai Zhou , Horst Stöcker

We propose a new method in which a generative network (GN) integrate into a reduced-order model (ROM) framework is used to solve inverse problems for partial differential equations (PDE). The aim is to match available measurements and…

Machine Learning · Computer Science 2025-06-17 Vinicius L. S. Silva , Claire E. Heaney , Nenko Nenov , Christopher C. Pain

Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis, continues to be a major global health threat despite being preventable and curable. This burden is particularly high in low and middle income countries.…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Greeshma K , Vishnukumar S

Tuberculosis is an infectious disease that is leading to the death of millions of people across the world. The mortality rate of this disease is high in patients suffering from immuno-compromised disorders. The early diagnosis of this…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 G Jignesh Chowdary , Suganya G , Premalatha M , Karunamurthy K

Ordinary differential equations (ODE) are a popular tool to model the spread of infectious diseases, yet they implicitly assume an exponential distribution to describe the flow from one infection state to another. However, scientific…

Numerical Analysis · Mathematics 2025-10-13 Anna Wendler , Lena Plötzke , Hannah Tritzschak , Martin J. Kühn

The dynamics of burning plasmas in tokamaks are crucial for advancing controlled thermonuclear fusion. This study applies the NeuralPlasmaODE, a multi-region multi-timescale transport model, to simulate the complex energy transfer processes…

Plasma Physics · Physics 2024-12-13 Zefang Liu , Weston M. Stacey

Reduced-order models (ROMs) are essential for rapid simulation of complex biomechanical systems and for bridging the gap between high fidelity models and clinical application. However, ROMs for tissue growth and remodeling (G&R) remain…

Computational Engineering, Finance, and Science · Computer Science 2026-04-16 Joel Laudo , Adrian Buganza Tepole

The MRI-derived brain network serves as a pivotal instrument in elucidating both the structural and functional aspects of the brain, encompassing the ramifications of diseases and developmental processes. However, prevailing methodologies,…

Machine Learning · Computer Science 2024-05-24 Haoteng Tang , Guodong Liu , Siyuan Dai , Kai Ye , Kun Zhao , Wenlu Wang , Carl Yang , Lifang He , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Black Sigatoka disease severely decreases global banana production, and climate change aggravates the problem by altering fungal species distributions. Due to the heavy financial burden of managing this infectious disease, farmers in…

Positive selection drives the emergence of adaptive mutations in Mycobacterium tuberculosis, shaping drug resistance, transmissibility, and virulence. Phylogenetic trees capture evolutionary relationships among isolates and provide a…

Populations and Evolution · Quantitative Biology 2025-10-13 Linfeng Wang , Susana Campino , Taane G. Clark , Jody E. Phelan

Learning dynamics governed by differential equations is crucial for predicting and controlling the systems in science and engineering. Neural Ordinary Differential Equation (NODE), a deep learning model integrated with differential…

Machine Learning · Computer Science 2021-11-09 Shiqi Gong , Qi Meng , Yue Wang , Lijun Wu , Wei Chen , Zhi-Ming Ma , Tie-Yan Liu

Background and Objective: Tuberculosis (TB) is a significant public health issue and a leading cause of death worldwide. Millions of deaths can be averted by early diagnosis and successful treatment of TB patients. Automated diagnosis of TB…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Anushikha Singh , Brejesh Lall , B. K. Panigrahi , Anjali Agrawal , Anurag Agrawal , Balamugesh Thangakunam , DJ Christopher

Channel prediction is critical to address the channel aging issue in mobile scenarios. Existing channel prediction techniques are mainly designed for discrete channel prediction, which can only predict the future channel in a fixed time…

Information Theory · Computer Science 2023-08-01 Mingyao Cui , Hao Jiang , Yuhao Chen , Yang Du , Linglong Dai

Estimating $T_2$ relaxation time distributions from multi-echo $T_2$-weighted MRI ($T_2W$) data can provide valuable biomarkers for assessing inflammation, demyelination, edema, and cartilage composition in various pathologies, including…

Signal Processing · Electrical Eng. & Systems 2023-05-19 Hadas Ben-Atya , Moti Freiman

Learning underlying dynamics from data is important and challenging in many real-world scenarios. Incorporating differential equations (DEs) to design continuous networks has drawn much attention recently, however, most prior works make…

Machine Learning · Computer Science 2023-02-03 Yesom Park , Jaemoo Choi , Changyeon Yoon , Chang hoon Song , Myungjoo Kang