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Physics-informed neural network architectures have emerged as a powerful tool for developing flexible PDE solvers which easily assimilate data, but face challenges related to the PDE discretization underpinning them. By instead adapting a…

Numerical Analysis · Mathematics 2020-12-11 Ravi G. Patel , Indu Manickam , Nathaniel A. Trask , Mitchell A. Wood , Myoungkyu Lee , Ignacio Tomas , Eric C. Cyr

Epidemiological models are best suitable to model an epidemic if the spread pattern is stationary. To deal with non-stationary patterns and multiple waves of an epidemic, we develop a hybrid model encompassing epidemic modeling, particle…

Machine Learning · Computer Science 2024-02-01 Naresh Kumar , Seba Susan

Reaction-diffusion epidemic models with vital dynamics are an important framework for describing the spatial and temporal spread of infectious diseases. In this work, we present a constraint-aware, physics-informed neural network (PINN)…

Dynamical Systems · Mathematics 2026-05-20 Achraf Zinihi , Matthias Ehrhardt

Machine learning has been an emerging tool for various aspects of infectious diseases including tuberculosis surveillance and detection. However, WHO provided no recommendations on using computer-aided tuberculosis detection software…

Computer Vision and Pattern Recognition · Computer Science 2020-08-04 Seelwan Sathitratanacheewin , Krit Pongpirul

In this paper, we model a nonlinear dynamics of infectious diseases transfer. Particularly, we study possible applications to tubercular infection in models with different profiles (peak values) of the population density dependence on…

We define a digital twin (DT) of a physical system governed by partial differential equations (PDEs) as a model for real-time simulations and control of the system behavior under changing conditions. We construct DTs using the…

Machine Learning · Computer Science 2025-01-14 Yifei Zong , Alexandre Tartakovsky

In order to simulate the spread of infectious diseases, many epidemiological models use systems of ordinary differential equations (ODEs) to describe the underlying dynamics. These models incorporate the implicit assumption, that the stay…

Dynamical Systems · Mathematics 2025-10-13 Lena Plötzke , Anna Wendler , René Schmieding , Martin J. Kühn

Throughout human history, epidemics have been a constant presence. Understanding their dynamics is essential to predict scenarios and make substantiated decisions. Mathematical models are powerful tools to describe an epidemic behavior.…

Systems and Control · Electrical Eng. & Systems 2024-07-26 Walter HMendes aselein , Diego Eckhard

Multiple Sclerosis is a degenerative condition of the central nervous system that affects nearly 2.5 million of individuals in terms of their physical, cognitive, psychological and social capabilities. Researchers are currently…

Machine Learning · Statistics 2016-12-05 Samuele Fiorini , Andrea Tacchino , Giampaolo Brichetto , Alessandro Verri , Annalisa Barla

This work proposes an extension of neural ordinary differential equations (NODEs) by introducing an additional set of ODE input parameters to NODEs. This extension allows NODEs to learn multiple dynamics specified by the input parameter…

Computational Physics · Physics 2021-11-17 Kookjin Lee , Eric J. Parish

Tuberculosis (TB) is a contagious bacterial airborne disease, and is one of the top 10 causes of death worldwide. According to the World Health Organization (WHO), around 1.8 billion people are infected with TB and 1.6 million deaths were…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Chirath Dasanayakaa , Maheshi Buddhinee Dissanayake

We present a modelling framework for the spreading of epidemics on temporal networks from which both the individual-based and pair-based models can be recovered. The proposed temporal pair-based model that is systematically derived from…

Physics and Society · Physics 2020-11-17 Rory Humphries , Kieran Mulchrone , Jamie Tratalos , Simon More , Philipp Hövel

Numerical simulation of ordinary differential equations (ODEs) can be challenging when the system exhibits high accelerations and rapidly changing dynamics. Under these conditions the ODE solver often needs to take very small time steps in…

Numerical Analysis · Mathematics 2026-05-11 Andrew Tagg , Andrew Frandsen , Andrew Ning

The standard way to estimate the parameters $\Theta_\text{SEIR}$ (e.g., the transmission rate $\beta$) of an SEIR model is to use grid search, where simulations are performed on each set of parameters, and the parameter set leading to the…

Machine Learning · Statistics 2021-06-01 Chun Fan , Yuxian Meng , Xiaofei Sun , Fei Wu , Tianwei Zhang , Jiwei Li

Modeling spreading processes in complex random networks plays an essential role in understanding and prediction of many real phenomena like epidemics or rumor spreading. The dynamics of such systems may be represented algorithmically by…

Social and Information Networks · Computer Science 2012-11-20 S. V. Ivanov , A. V. Boukhanovsky , P. M. A. Sloot

Accurately predicting long-horizon molecular dynamics (MD) trajectories remains a significant challenge, as existing deep learning methods often struggle to retain fidelity over extended simulations. We hypothesize that one key factor…

Machine Learning · Computer Science 2025-07-01 Fang Sun , Zijie Huang , Haixin Wang , Huacong Tang , Xiao Luo , Wei Wang , Yizhou Sun

Up to now, the effects of having heterogeneous networks of contacts have been studied mostly for diseases which are not persistent in time, i.e., for diseases where the infectious period can be considered very small compared to the lifetime…

Physics and Society · Physics 2015-05-18 J. Sanz , L. M. Floria , Y. Moreno

Neural ODEs (NODEs) have emerged as powerful tools for modeling time series data, offering the flexibility to adapt to varying input scales and capture complex dynamics. However, they face significant challenges: first, their reliance on…

Machine Learning · Computer Science 2025-10-07 Muhao Guo , Yang Weng

Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a critical global health issue, necessitating timely diagnosis and treatment. Current methods for detecting tuberculosis bacilli from bright field microscopic sputum smear…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Greeshma K , Vishnukumar S

The interplay between disease spreading and personal risk perception is of key importance for modelling the spread of infectious diseases. We propose a planar system of ordinary differential equations (ODEs) to describe the co-evolution of…

Dynamical Systems · Mathematics 2023-05-09 Massimo A. Achterberg , Mattia Sensi
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