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Type 1 Diabetes (T1D) management is a complex task due to many variability factors. Artificial Pancreas (AP) systems have alleviated patient burden by automating insulin delivery through advanced control algorithms. However, the…

Machine Learning · Computer Science 2025-11-03 Stefano De Carli , Nicola Licini , Davide Previtali , Fabio Previdi , Antonio Ferramosca

Recently, Neural Ordinary Differential Equations has emerged as a powerful framework for modeling physical simulations without explicitly defining the ODEs governing the system, but instead learning them via machine learning. However, the…

Session-based recommendation (SBR) aims to predict the user next action based on the ongoing sessions. Recently, there has been an increasing interest in modeling the user preference evolution to capture the fine-grained user interests.…

Information Retrieval · Computer Science 2022-08-23 Jiayan Guo , Peiyan Zhang , Chaozhuo Li , Xing Xie , Yan Zhang , Sunghun Kim

Computing properties of molecular systems rely on estimating expectations of the (unnormalized) Boltzmann distribution. Molecular dynamics (MD) is a broadly adopted technique to approximate such quantities. However, stable simulations rely…

Chemical Physics · Physics 2023-10-31 Mathias Schreiner , Ole Winther , Simon Olsson

This study presents a neural network-enhanced approach to modeling disease spread dynamics over time and space. Neural networks are used to estimate time-varying parameters, with two calibration methods explored: Approximate Bayesian…

Quantitative Methods · Quantitative Biology 2024-10-29 Randy L. Caga-anan

The SIR model is a classical model characterizing the spreading of infectious diseases. This model describes the time-dependent quantity changes among Susceptible, Infectious, and Recovered groups. By introducing space-depend effects such…

Quantitative Methods · Quantitative Biology 2024-09-18 Md Abu Talha , Yongjia Xu , Shan Zhao , Weihua Geng

We introduce a new tuberculosis (TB) mathematical model, with $25$ state-space variables where $15$ are evolution disease states (EDSs), which generalises previous models and takes into account the (seasonal) flux of populations between a…

Populations and Evolution · Quantitative Biology 2018-05-25 Eugenio M. Rocha , Cristiana J. Silva , Delfim F. M. Torres

Physics-Informed Neural Networks (PINNs) and Neural Ordinary Differential Equations (NODEs) represent two distinct machine learning frameworks for modeling nonlinear neuronal dynamics. This study systematically evaluates their performance…

Dynamical Systems · Mathematics 2026-03-31 Nikolaos M. Matzakos , Chrisovalantis Sfyrakis

The transmission dynamics of Tuberculosis (TB) involve complex epidemiological and socio-economical interactions between individuals living in highly distinct regional conditions. The level of exogenous reinfection and first time infection…

Populations and Evolution · Quantitative Biology 2016-09-15 Victor Moreno , Baltazar Espinoza , Kamal Barley , Marlio Paredes , Derdei Bichara , Anuj Mubayi , Carlos Castillo-Chavez

Liver cirrhosis is a major global health problem causing millions of deaths annually, and timely detection with aggressive treatment can significantly improve patients' quality of life. Modelling complex diseases from biomedical data is…

Other Quantitative Biology · Quantitative Biology 2026-04-29 Xueyuan Huang , Yuheng Wang , Yuanzhi He , Siqi Gou , Lu Bai , Wenqian Wu , Peifeng Liu , Aijia Wang , Tianhui Fan , Ze Zhou , Jiayu Xu

A nonlinear partial differential equation (PDE) based compartmental model of COVID-19 provides a continuous trace of infection over space and time. Finer resolutions in the spatial discretization, the inclusion of additional model…

Computational Engineering, Finance, and Science · Computer Science 2022-08-04 Sudhi P. V. , Victorita Dolean , Pierre Jolivet , Brandon Robinson , Jodi D. Edwards , Tetyana Kendzerska , Abhijit Sarkar

This paper presents a method for modeling transient fluid flow in subsurface reservoir systems based on the developed neural operator architecture (TFNO-opt). Reservoir systems are complex dynamic objects with distributed parameters…

Machine Learning · Computer Science 2025-10-21 Daniil D. Sirota , Sergey A. Khan , Sergey L. Kostikov , Kirill A. Butov

Tuberculosis (TB) remains one of the leading causes of mortality worldwide, particularly in resource-limited countries. Chest X-ray (CXR) imaging serves as an accessible and cost-effective diagnostic tool but requires expert interpretation,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Marshal Ashif Shawkat , Moidul Hasan , Taufiq Hasan

Causal inference in continuous-time sequential decision problems is challenged by hidden confounders. We show that, in latent state-space models with time-varying interventions, observability of the latent dynamics from observed data is…

Machine Learning · Computer Science 2026-05-14 Jennifer Wendland , Nicolas Freitag , Maik Kschischo

Mathematical modelling can help to explain the nature and dynamics of infection transmissions, as well as support a policy for implementing those strategies that are most likely to bring public health and economic benefits. The paper…

Optimization and Control · Mathematics 2015-09-01 Roman Denysiuk , Cristiana J. Silva , Delfim F. M. Torres

Scientific machine learning is increasingly used to build surrogate models, yet most models are trained under a restrictive assumption in which future data follow the same distribution as the training set. In practice, new experimental…

Machine Learning · Computer Science 2026-04-20 Mahmoud Elhadidy , Roshan M. D'Souza , Amirhossein Arzani

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li

In this study, a new and natural way of constructing a stochastic Susceptible-Infected-Susceptible (SIS) model is proposed. This approach is natural in the sense that the disease transmission rate, $\beta$, is substituted with a generic,…

Probability · Mathematics 2025-11-07 Berk Tan Perçin

While data-driven methods such as neural operator have achieved great success in solving differential equations (DEs), they suffer from domain shift problems caused by different learning environments (with data bias or equation changes),…

Machine Learning · Computer Science 2025-05-27 Hao-Ran Yang , Chuan-Xian Ren

We propose an extension of the classical susceptible infectious recovered (SIR) model that incorporates the effects of spatial propagation of an epidemic through a small number of additional compartments. The model is designed to capture…

Numerical Analysis · Mathematics 2026-03-02 M. Soledad Aronna , Mariana Bergonzi , Ernesto Kofman
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