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Most current molecular language models transfer the masked language model or image-text generation model from natural language processing to molecular field. However, molecules are not solely characterized by atom/bond symbols; they…

Emerging Technologies · Computer Science 2024-11-26 Yifan Wu , Min Zeng , Yang Li , Yang Zhang , Min Li

We present a modular framework powered by large language models (LLMs) that automates and streamlines key tasks across the early-stage computational drug discovery pipeline. By combining LLM reasoning with domain-specific tools, the…

While large language models (LLMs) are still being adopted to new domains and utilized in novel applications, we are experiencing an influx of the new generation of foundation models, namely multi-modal large language models (MLLMs). These…

Computation and Language · Computer Science 2024-08-23 Kian Ahrabian , Zhivar Sourati , Kexuan Sun , Jiarui Zhang , Yifan Jiang , Fred Morstatter , Jay Pujara

Multi-modal Large Language Models (MLLMs) have demonstrated remarkable capabilities in understanding and generating content across various modalities, such as images and text. However, their interpretability remains a challenge, hindering…

Computer Vision and Pattern Recognition · Computer Science 2024-05-29 Loris Giulivi , Giacomo Boracchi

Multimodal learning, which integrates data from diverse sensory modes, plays a pivotal role in artificial intelligence. However, existing multimodal learning methods often struggle with challenges where some modalities appear more dominant…

Machine Learning · Computer Science 2024-04-02 Xiaohui Zhang , Jaehong Yoon , Mohit Bansal , Huaxiu Yao

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

For data-constrained, complex and dynamic industrial environments, there is a critical need for transferable and multimodal methodologies to enhance anomaly detection and therefore, prevent costs associated with system failures. Typically,…

Multimodal learning enhances the performance of various machine learning tasks by leveraging complementary information across different modalities. However, existing methods often learn multimodal representations that retain substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Tong Zhang , Shu Shen , C. L. Philip Chen

Transformer-based Large Language Models (LLMs) traditionally rely on final-layer loss for training and final-layer representations for predictions, potentially overlooking the predictive power embedded in intermediate layers. Surprisingly,…

Computation and Language · Computer Science 2024-10-18 Haoyan Luo , Lucia Specia

Molecular representation learning plays a crucial role in various downstream tasks, such as molecular property prediction and drug design. To accurately represent molecules, Graph Neural Networks (GNNs) and Graph Transformers (GTs) have…

Machine Learning · Computer Science 2025-02-07 Jingjing Hu , Dan Guo , Zhan Si , Deguang Liu , Yunfeng Diao , Jing Zhang , Jinxing Zhou , Meng Wang

In recent years, multimodal large language models (MLLMs) have made significant strides by training on vast high-quality image-text datasets, enabling them to generally understand images well. However, the inherent difficulty in explicitly…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Yuanze Lin , Yunsheng Li , Dongdong Chen , Weijian Xu , Ronald Clark , Philip Torr , Lu Yuan

Protein inverse folding is a fundamental problem in bioinformatics, aiming to recover the amino acid sequences from a given protein backbone structure. Despite the success of existing methods, they struggle to fully capture the intricate…

Machine Learning · Computer Science 2024-12-13 Chenglin Wang , Yucheng Zhou , Zijie Zhai , Jianbing Shen , Kai Zhang

End-to-end autonomous driving systems built on Vision Language Models (VLMs) have shown significant promise, yet their reliance on autoregressive architectures introduces some limitations for real-world applications. The sequential,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Can Cui , Yupeng Zhou , Juntong Peng , Sung-Yeon Park , Zichong Yang , Prashanth Sankaranarayanan , Jiaru Zhang , Ruqi Zhang , Ziran Wang

The development of large language models and multi-modal models has enabled the appealing idea of generating novel molecules from text descriptions. Generative modeling would shift the paradigm from relying on large-scale chemical screening…

Machine Learning · Computer Science 2025-08-25 Yifan Deng , Spencer S. Ericksen , Anthony Gitter

Large Language Models (LLMs) have demonstrated exceptional proficiency in text understanding and embedding tasks. However, their potential in multimodal representation, particularly for item-to-item (I2I) recommendations, remains…

Information Retrieval · Computer Science 2025-01-22 Chao Zhang , Haoxin Zhang , Shiwei Wu , Di Wu , Tong Xu , Xiangyu Zhao , Yan Gao , Yao Hu , Enhong Chen

Medical vision--language models (MVLMs) are increasingly used as perceptual backbones in radiology pipelines and as the visual front end of multimodal assistants, yet their reliability under real clinical workflows remains underexplored.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Xiang Chen , Fangfang Yang , Chunlei Meng , Yuxian Dong , Ang Li , Yiwei Wei , Jiahuan Long , Jiujiang Guo , Chengyin Hu

Diffusion language models have recently emerged as a competitive alternative to autoregressive language models. Beyond next-token generation, they are more efficient and flexible by enabling parallel and any-order token generation. However,…

Machine Learning · Computer Science 2025-11-18 Chenxiao Yang , Cai Zhou , David Wipf , Zhiyuan Li

Recently, large language models (LLMs) have shown significant progress, approaching human perception levels. In this work, we demonstrate that despite these advances, LLMs still struggle to reason using molecular structural information.…

Machine Learning · Computer Science 2025-05-26 Yunhui Jang , Jaehyung Kim , Sungsoo Ahn

Face recognition systems are increasingly vulnerable to morphing attacks, where a composite image is crafted to match multiple identities, enabling unauthorized access and identity fraud. Existing detection methods identify morphed images…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Nitish Shukla , Arun Ross

Generating molecular structures with desired properties is a critical task with broad applications in drug discovery and materials design. We propose 3M-Diffusion, a novel multi-modal molecular graph generation method, to generate diverse,…

Machine Learning · Computer Science 2024-10-04 Huaisheng Zhu , Teng Xiao , Vasant G Honavar
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