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The immersed boundary (IB) method is a mathematical framework for fluid-structure interaction problems (FSI) that was originally developed to simulate flows around heart valves. Direct comparison of FSI simulations around heart valves…

Hemodynamic analysis is essential for predicting aneurysm rupture and guiding treatment. While magnetic resonance flow imaging enables time-resolved volumetric blood velocity measurements, its low spatiotemporal resolution and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Kyriakos Flouris , Moritz Halter , Yolanne Y. R. Lee , Samuel Castonguay , Luuk Jacobs , Pietro Dirix , Jonathan Nestmann , Sebastian Kozerke , Ender Konukoglu

Accurate and rapid estimation of hemodynamic metrics, such as pressure and wall shear stress (WSS), is important for assessing the severity of Coronary Artery Disease (CAD). Existing approaches, including invasive Fractional Flow Reserve…

Computational Engineering, Finance, and Science · Computer Science 2026-05-28 Reza Akbarian Bafghi , Sukirt Thakur , Maziar Raissi

We investigate the use of reduced-order modelling to run discrete element simulations at higher speeds. Taking a data-driven approach, we run many offline simulations in advance and train a model to predict the velocity field from the mass…

Computational Physics · Physics 2021-03-02 Erik Wallin , Martin Servin

Three intra-aortic blood pumps were evaluated and compared using CFD simulations. The aim of this study is to evaluate the hemodynamic performance and calculate the hemolytic potential of the pumps. The flow fields generated by the pumps…

Medical Physics · Physics 2026-03-31 Osman Aycan , Yeojin Park , Lyes Kadem

To accurately simulate all phases of the cardiac cycle, computational models of hemodynamics in heart chambers need to include a sufficiently faithful model of cardiac valves. This can be achieved efficiently through resistive methods, and…

Numerical Analysis · Mathematics 2025-06-05 Michele Bucelli , Luca Dede'

Local hemodynamic forces play an important role in determining the functional significance of coronary arterial stenosis and understanding the mechanism of coronary disease progression. Computational fluid dynamics (CFD) have been widely…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Ziyu Ni , Linda Wei , Lijian Xu , Simon Yu , Qing Xia , Hongsheng Li , Shaoting Zhang

Modeling cardiovascular anatomies poses a significant challenge due to their complex, irregular structures and inherent pathological conditions. Numerical simulations, while accurate, are often computationally expensive, limiting their…

Machine Learning · Computer Science 2025-03-25 Navaneeth N , Souvik Chakraborty

In this paper, we present two deep learning-based hybrid data-driven reduced order models for the prediction of unsteady fluid flows. The first model projects the high-fidelity time series data from a finite element Navier-Stokes solver to…

Fluid Dynamics · Physics 2024-05-29 Sandeep Reddy Bukka , Rachit Gupta , Allan Ross Magee , Rajeev Kumar Jaiman

The trade-off between model fidelity and computational cost remains a central challenge in the computational modeling of extrusion-based 3D printing, particularly for real time optimization and control. Although high fidelity simulations…

Fluid Dynamics · Physics 2026-04-14 Mandana Mohammadi Looey , Marissa Loraine Scalise , Amrita Basak , Satadru Dey

We propose a data-driven filtered reduced order model (DDF-ROM) framework for the numerical simulation of fluid flows. The novel DDF-ROM framework consists of two steps: (i) In the first step, we use explicit ROM spatial filtering of the…

Fluid Dynamics · Physics 2017-09-14 X. Xie , M. Mohebujjaman , L. G. Rebholz , T. Iliescu

High-fidelity computational fluid dynamics (CFD) simulations are widely used to analyze nuclear reactor transients, but are computationally expensive when exploring large parameter spaces. Multifidelity surrogate models offer an approach to…

Machine Learning · Computer Science 2026-03-17 Meredith Eaheart , Majdi I. Radaideh

This article presents a general reduced order model (ROM) framework for addressing fluid dynamics problems involving time-dependent geometric parametrisations. The framework integrates Proper Orthogonal Decomposition (POD) and Empirical…

Fluid Dynamics · Physics 2024-05-07 J. R. Bravo , G. Stabile , M. Hess , J. A. Hernandez , R. Rossi , G. Rozza

Accurate 3D aortic construction is crucial for clinical diagnosis, preoperative planning, and computational fluid dynamics (CFD) simulations, as it enables the estimation of critical hemodynamic parameters such as blood flow velocity,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Delin An , Pan Du , Jian-Xun Wang , Chaoli Wang

It is known that the maximum diameter for the rupture-risk assessment of the abdominal aortic aneurysm is a generally good method, but not sufficient. Alternative features obtained with computational modeling may provide additional useful…

Computational Engineering, Finance, and Science · Computer Science 2020-03-16 Shanlin Qin , Rongliang Chen , Bokai Wu , Jia Liu , Wen-Shin Shiu , Zhengzheng Yan , Xiao-Chuan Cai

The emergence of computational fluid dynamics (CFD) enabled the simulation of intricate transport processes, including flow in physiological structures, such as blood vessels. While these so-called hemodynamic simulations offer…

Accurate 3D cardiac reconstruction from cine magnetic resonance imaging (cMRI) is crucial for improved cardiovascular disease diagnosis and understanding of the heart's motion. However, current cardiac MRI-based reconstruction technology…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Xiaoxiao He , Chaowei Tan , Ligong Han , Bo Liu , Leon Axel , Kang Li , Dimitris N. Metaxas

The goal of this paper is to investigate the validity of a hybrid embedded/homogenized in-silico approach for modeling perfusion through solid tumors. The rationale behind this novel idea is that only the larger blood vessels have to be…

Computational Engineering, Finance, and Science · Computer Science 2021-07-15 Johannes Kremheller , Sebastian Brandstaeter , Bernhard A. Schrefler , Wolfgang A. Wall

Cardiac magnetic resonance imaging (MRI) requires reconstructing a real-time video of a beating heart from continuous highly under-sampled measurements. This task is challenging since the object to be reconstructed (the heart) is…

Image and Video Processing · Electrical Eng. & Systems 2024-01-12 Johannes F. Kunz , Stefan Ruschke , Reinhard Heckel

The typical size of computational meshes needed for realistic geometries and high-speed flow conditions makes Computational Fluid Dynamics (CFD) impractical for full-mission performance prediction and control. Reduced-Order Models (ROMs) in…

Fluid Dynamics · Physics 2023-06-09 Haitz Sáez de Ocáriz Borde , Pietro Innocenzi , Flavio Savarino