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Prediction of the blood flow characteristics is of utmost importance for understanding the behavior of the blood arterial network, especially in the presence of vascular diseases such as stenosis. Computational fluid dynamics (CFD) has…

Machine Learning · Computer Science 2021-11-11 Mohammad Farajtabar , Mohit Biglarian , Morteza Miansari

Cardiovascular diseases (CVDs) are the leading causes of mortality worldwide. The contraction and relaxation of left ventricle (LV) is the main driving force of blood circulation. Altered LV hemodynamics is believed to be associated with…

Medical Physics · Physics 2019-11-04 Fanwei Kong , Christoph Augustin , Kevin Sack , Shawn Shadden

In this work, a new hybrid predictive Reduced Order Model (ROM) is proposed to solve reacting flow problems. This algorithm is based on a dimensionality reduction using Proper Orthogonal Decomposition (POD) combined with deep learning…

Machine Learning · Computer Science 2023-01-25 Adrián Corrochano , Rodolfo S. M. Freitas , Alessandro Parente , Soledad Le Clainche

Magnetic resonance imaging (MRI) can estimate three-dimensional (3D) time-resolved relative pressure fields using 4D-flow MRI, thereby providing rich pressure field information. Clinical alternatives include catheterization and Doppler…

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

Medical Physics · Physics 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

Image-based computational fluid dynamics (CFD) modeling enables derivation of hemodynamic information, which has become a paradigm in cardiovascular research and healthcare. Nonetheless, the predictive accuracy largely depends on precisely…

Fluid Dynamics · Physics 2021-07-20 Han Gao , Xueyu Zhu , Jian-Xun Wang

4D flow MRI is a non-invasive imaging method that can measure blood flow velocities over time. However, the velocity fields detected by this technique have limitations due to low resolution and measurement noise. Coordinate-based neural…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Simone Saitta , Marcello Carioni , Subhadip Mukherjee , Carola-Bibiane Schönlieb , Alberto Redaelli

Reduced-order models that accurately abstract high fidelity models and enable faster simulation is vital for real-time, model-based diagnosis applications. In this paper, we outline a novel hybrid modeling approach that combines machine…

Signal Processing · Electrical Eng. & Systems 2020-03-06 Ion Matei , Johan de Kleer , Alexander Feldman , Rahul Rai , Souma Chowdhury

Computational Intelligence (CI) techniques have shown great potential as a surrogate model of expensive physics simulation, with demonstrated ability to make fast predictions, albeit at the expense of accuracy in some cases. For many…

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

A reduced-order model based on Proper Orthogonal Decomposition (POD) is proposed for the bidomain equations of cardiac electrophysiology. Its accuracy is assessed through electrocardiograms in various configurations, including myocardium…

Numerical Analysis · Mathematics 2012-07-23 Muriel Boulakia , Elisa Schenone , Jean-Frédéric Gerbeau

In this work, we consider two kinds of model reduction techniques to simulate blood flow through the largest systemic arteries, where a stenosis is located in a peripheral artery i.e. in an artery that is located far away from the heart.…

Numerical Analysis · Mathematics 2018-10-09 Tobias Köppl , Gabriele Santin , Bernard Haasdonk , Rainer Helmig

Cardiovascular diseases, particularly arrhythmias, remain a leading global cause of mortality, necessitating continuous monitoring via the Internet of Medical Things (IoMT). However, state-of-the-art deep learning approaches often impose…

Machine Learning · Computer Science 2026-01-05 Moirangthem Tiken Singh , Manibhushan Yaikhom

Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

Machine Learning · Computer Science 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Physically plausible fluid simulations play an important role in modern computer graphics and engineering. However, in order to achieve real-time performance, computational speed needs to be traded-off with physical accuracy. Surrogate…

Fluid Dynamics · Physics 2021-05-19 Nils Wandel , Michael Weinmann , Reinhard Klein

We propose a novel neural deformable model (NDM) targeting at the reconstruction and modeling of 3D bi-ventricular shape of the heart from 2D sparse cardiac magnetic resonance (CMR) imaging data. We model the bi-ventricular shape using…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Meng Ye , Dong Yang , Mikael Kanski , Leon Axel , Dimitris Metaxas

4D flow magnetic resonance imaging (MRI) is a reliable, non-invasive approach for estimating blood flow velocities, vital for cardiovascular diagnostics. Unlike conventional MRI focused on anatomical structures, 4D flow MRI requires high…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Sun Jo , Seok Young Hong , JinHyun Kim , Seungmin Kang , Ahjin Choi , Don-Gwan An , Simon Song , Je Hyeong Hong

Computational fluid dynamics (CFD) simulations play an important role in engineering science and applications, however, it is not applicable for problems requiring a large number of repeated calculations. Accordingly, many reduced-order…

Fluid Dynamics · Physics 2026-05-28 Shan Ding , Yongfu Tian , Rui Yang

Coronary heart disease (CHD) remains a top reason of mortality worldwide. This study introduces a novel approach by integrating patient-specific Multi-slice CT scans into CAD models and employing a one-dimensional numerical framework to…

Medical Physics · Physics 2025-07-01 Oeshee Roy , Priyanshu Ghosh , Sayan Karmakar , Supratim Saha

Predictive high-fidelity finite element simulations of human cardiac mechanics co\-mmon\-ly require a large number of structural degrees of freedom. Additionally, these models are often coupled with lumped-parameter models of hemodynamics.…

Computational Engineering, Finance, and Science · Computer Science 2020-02-18 Martin R. Pfaller , Maria Cruz Varona , Johannes Lang , Cristóbal Bertoglio , Wolfgang A. Wall
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