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A method is presented for the registration of MRA and 4D Flow images, with the goal of calculating blood flow properties using both modalities simultaneously. In particular, the method produces an alignment of segmentations of vessel…

Quantitative Methods · Quantitative Biology 2025-04-28 Dan Lior , Craig G. Rusin , Justin Weigand , Kristina V. Montez , Yimo Wang , Silvana Molossi , Daniel J. Penny , Charles Puelz

The use of deep learning methods for modeling fluid flow has drawn a lot of attention in the past few years. In situations where conventional numerical approaches can be computationally expensive, these techniques have shown promise in…

A major challenge in the computational fluid dynamics modeling of the heart function is the simulation of isovolumetric phases when the hemodynamics problem is driven by a prescribed boundary displacement. During such phases, both…

Numerical Analysis · Mathematics 2022-08-25 Alberto Zingaro , Michele Bucelli , Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

The rapidly increasing prevalence of debilitating breathing disorders, such as chronic obstructive pulmonary disease (COPD), calls for a meaningful integration of artificial intelligence (AI) into healthcare. While this promises improved…

Medical Physics · Physics 2022-10-07 Harry J. Davies , Ghena Hammour , Hongjian Xiao , Danilo P. Mandic

Blood flow imaging provides important information for hemodynamic behavior within the vascular system and plays an essential role in medical diagnosis and treatment planning. However, obtaining high-quality flow images remains a significant…

Numerical Analysis · Mathematics 2026-04-02 Han Zhang , Xue-Cheng Tai , Jean-Michel Morel , Raymond H. Chan

Cardiovascular diseases are among the most important causes of global mortality. Computational Fluid Dynamics (CFD) is a powerful research tool that analyzes the hemodynamics of artery and blood flow patterns. In this study, CFD simulations…

Fluid Dynamics · Physics 2023-09-12 Osman Aycan , Adnan Topuz , Lyes Kadem

Four-dimensional MRI (4D-MRI) is an promising technique for capturing respiratory-induced motion in radiation therapy planning and delivery. Conventional 4D reconstruction methods, which typically rely on phase binning or separate template…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Xinyang Wu , Muheng Li , Xia Li , Orso Pusterla , Sairos Safai , Philippe C. Cattin , Antony J. Lomax , Ye Zhang

We propose a hemodynamic reduced-order model bridging macroscopic and meso-scopic blood flow circulation scales from arteries to capillaries. In silico tree like vascular geometries, mathematically described by graphs, are synthetically…

Medical Physics · Physics 2019-07-29 Olivier Adjoua , Stéphanie Pitre-Champagnat , Didier Lucor

Cardiovascular disease is the leading global cause of mortality, with coronary artery disease (CAD) as its most prevalent form, necessitating early risk prediction. While 3D coronary artery digital twins reconstructed from imaging offer…

Computational models of cardiac structure and function are increasingly central to the development of subject-specific cardiac digital twins, enabling improved characterization of contractile dysfunction, pathological remodeling, and…

This study leverages convolutional neural networks to enhance the temporal resolution of 3D angiography in intracranial aneurysms focusing on the reconstruction of volumetric contrast data from sparse and limited projections. Three…

Quantifying hemodynamics in the curved segments of the intracranial internal carotid artery is a core challenge in diagnosing vascular stenosis. Conventional full-field imaging, such as 4D Flow MRI, is costly and difficult to widely…

Medical Physics · Physics 2026-05-14 Jingtai Song , Qinsheng Zhu , Xiaodong Xing , Yufeng Tang , Zhiyun Zhang , Xianwen Zhang , Hao Wu

This contribution describes the implementation of a data--driven shape optimization pipeline in a naval architecture application. We adopt reduced order models (ROMs) in order to improve the efficiency of the overall optimization, keeping a…

Numerical Analysis · Mathematics 2024-01-22 Nicola Demo , Giulio Ortali , Gianluca Gustin , Gianluigi Rozza , Gianpiero Lavini

This paper deals with fast simulations of the haemodynamics in large arteries by considering a reduced model of the associated fluid-structure interaction problem, which in turn allows an additional reduction in terms of the numerical…

Numerical Analysis · Mathematics 2018-01-19 Claudia M. Colciago , Simone Deparis

Subsurface simulations use computational models to predict the flow of fluids (e.g., oil, water, gas) through porous media. These simulations are pivotal in industrial applications such as petroleum production, where fast and accurate…

Machine Learning · Computer Science 2022-06-16 Tailin Wu , Qinchen Wang , Yinan Zhang , Rex Ying , Kaidi Cao , Rok Sosič , Ridwan Jalali , Hassan Hamam , Marko Maucec , Jure Leskovec

This study performs parameter inference in a partial differential equations system of pulmonary circulation. We use a fluid dynamics network model that takes selected parameter values and mimics the behaviour of the pulmonary haemodynamics…

We propose a novel method for non-rigid 3-D motion correction of orthogonally raster-scanned optical coherence tomography angiography volumes. This is the first approach that aligns predominantly axial structural features like retinal…

Cerebral aneurysms and arteriovenous malformations are life-threatening hemodynamic pathologies of the brain. While surgical intervention is often essential to prevent fatal outcomes, it carries significant risks both during the procedure…

Machine Learning · Computer Science 2026-03-17 Irem Topal , Alexander Cherevko , Yuri Bugay , Maxim Shishlenin , Jean Barbier , Deniz Eroglu , Édgar Roldán , Roman Belousov

In this article, we introduce a modular hybrid analysis and modeling (HAM) approach to account for hidden physics in reduced order modeling (ROM) of parameterized systems relevant to fluid dynamics. The hybrid ROM framework is based on…

Computational Physics · Physics 2020-04-22 Suraj Pawar , Shady E. Ahmed , Omer San , Adil Rasheed

Numerical simulations are a valuable research and layout tool for fluid flow problems, yet repeated evaluations of parametrized problems, necessary to solve optimization problems, can be very costly. One option to speed up this process is…

Fluid Dynamics · Physics 2025-02-28 Marian Staggl , Wolfgang Sanz , Paul Pieringer