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Large language models (LLMs) have transformed natural language processing (NLP), enabling diverse applications by integrating large-scale pre-trained knowledge. However, their static knowledge limits dynamic reasoning over external…

Computation and Language · Computer Science 2025-09-26 Harshad Khadilkar , Abhay Gupta

Large Language Models (LLMs) demonstrate strong reasoning abilities but face limitations such as hallucinations and outdated knowledge. Knowledge Graph (KG)-based Retrieval-Augmented Generation (RAG) addresses these issues by grounding LLM…

Computation and Language · Computer Science 2025-03-04 Mufei Li , Siqi Miao , Pan Li

Effectively retrieving, reasoning, and understanding multimodal information remains a critical challenge for agentic systems. Traditional Retrieval-augmented Generation (RAG) methods rely on linear interaction histories, which struggle to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Qiuchen Wang , Shihang Wang , Yu Zeng , Qiang Zhang , Fanrui Zhang , Zhuoning Guo , Bosi Zhang , Wenxuan Huang , Lin Chen , Zehui Chen , Pengjun Xie , Ruixue Ding

Retrieval-Augmented Generation (RAG) mitigates hallucinations in Multimodal Large Language Models (MLLMs), yet existing systems struggle with complex cross-modal reasoning. Flat vector retrieval often ignores structural dependencies, while…

Information Retrieval · Computer Science 2026-04-08 Sijun Dai , Qiang Huang , Xiaoxing You , Jun Yu

This paper presents RAG-KG-IL, a novel multi-agent hybrid framework designed to enhance the reasoning capabilities of Large Language Models (LLMs) by integrating Retrieval-Augmented Generation (RAG) and Knowledge Graphs (KGs) with an…

Computation and Language · Computer Science 2025-03-19 Hong Qing Yu , Frank McQuade

The rapid evolution of Retrieval-Augmented Generation (RAG) toward multimodal, high-stakes enterprise applications has outpaced the development of domain specific evaluation benchmarks. Existing datasets often rely on general-domain corpora…

Artificial Intelligence · Computer Science 2026-01-23 Chandan Kumar Sahu , Premith Kumar Chilukuri , Matthew Hetrich

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Medication recommendations have become an important task in the healthcare domain, especially in measuring the accuracy and safety of medical dialogue systems (MDS). Different from the recommendation task based on electronic health records…

Computation and Language · Computer Science 2025-05-20 Jialun Zhong , Yanzeng Li , Sen Hu , Yang Zhang , Teng Xu , Lei Zou

Recently, Retrieval-Augmented Generation (RAG) has achieved remarkable success in addressing the challenges of Large Language Models (LLMs) without necessitating retraining. By referencing an external knowledge base, RAG refines LLM…

Artificial Intelligence · Computer Science 2024-09-11 Boci Peng , Yun Zhu , Yongchao Liu , Xiaohe Bo , Haizhou Shi , Chuntao Hong , Yan Zhang , Siliang Tang

Synthetic Lethal (SL) relationships, though rare among the vast array of gene combinations, hold substantial promise for targeted cancer therapy. Despite advancements in AI model accuracy, there is still a significant need among domain…

Human-Computer Interaction · Computer Science 2024-07-23 Haoran Jiang , Shaohan Shi , Shuhao Zhang , Jie Zheng , Quan Li

Retrieval Augmented Generation (RAG) has made significant strides in overcoming key limitations of large language models, such as hallucination, lack of contextual grounding, and issues with transparency. However, traditional RAG systems…

Artificial Intelligence · Computer Science 2026-02-24 Yash Saxena , Manas Gaur

Retrieval-Augmented Generation (RAG) has become a core paradigm for enhancing factual grounding and multi-hop reasoning in Large Language Models (LLMs). Traditional text-based RAG often retrieves logically irrelevant pseudo-evidence, while…

Artificial Intelligence · Computer Science 2026-05-08 Jiarui Zhong , Hong Cai Chen

Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

Machine Learning · Computer Science 2025-02-25 Ziwei Yang , Zheng Chen , Xin Liu , Rikuto Kotoge , Peng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

Temporal knowledge graph reasoning (TKGR) aims to predict future events by inferring missing entities with dynamic knowledge structures. Existing LLM-based reasoning methods prioritize contextual over structural relations, struggling to…

Machine Learning · Computer Science 2026-01-30 Shiqi Fan , Quanming Yao , Hongyi Nie , Wentao Ma , Zhen Wang , Wen Hua

Recent proprietary large language models (LLMs), such as GPT-4, have achieved a milestone in tackling diverse challenges in the biomedical domain, ranging from multiple-choice questions to long-form generations. To address challenges that…

Computation and Language · Computer Science 2024-06-19 Minbyul Jeong , Jiwoong Sohn , Mujeen Sung , Jaewoo Kang

Large language models equipped with retrieval-augmented generation (RAG) represent a burgeoning field aimed at enhancing answering capabilities by leveraging external knowledge bases. Although the application of RAG with language-only…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Cheng Tan , Jingxuan Wei , Linzhuang Sun , Zhangyang Gao , Siyuan Li , Bihui Yu , Ruifeng Guo , Stan Z. Li

Despite notable advancements in Retrieval-Augmented Generation (RAG) systems that expand large language model (LLM) capabilities through external retrieval, these systems often struggle to meet the complex and diverse needs of real-world…

Computation and Language · Computer Science 2025-03-13 Jinyu Wang , Jingjing Fu , Rui Wang , Lei Song , Jiang Bian

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

Computation and Language · Computer Science 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang

Recent advances in large language models (LLMs) have led to impressive progress in natural language generation, yet their tendency to produce hallucinated or unsubstantiated content remains a critical concern. To improve factual…

Computation and Language · Computer Science 2025-05-20 Xukai Liu , Ye Liu , Shiwen Wu , Yanghai Zhang , Yihao Yuan , Kai Zhang , Qi Liu

Large language models (LLMs) struggle with the factual error during inference due to the lack of sufficient training data and the most updated knowledge, leading to the hallucination problem. Retrieval-Augmented Generation (RAG) has gained…

Information Retrieval · Computer Science 2026-01-22 Zulun Zhu , Tiancheng Huang , Kai Wang , Junda Ye , Xinghe Chen , Siqiang Luo
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